Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Jörg Hager"'
Autor:
Simona Bartova, Francisco Madrid-Gambin, Luis Fernández, Jerome Carayol, Emmanuelle Meugnier, Bérénice Segrestin, Pauline Delage, Nathalie Vionnet, Alexia Boizot, Martine Laville, Hubert Vidal, Santiago Marco, Jörg Hager, Sofia Moco
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Introduction and aimsDietary polyphenols have long been associated with health benefits, including the prevention of obesity and related chronic diseases. Overfeeding was shown to rapidly induce weight gain and fat mass, associated with mild insulin
Externí odkaz:
https://doaj.org/article/7bdc004491e44fed924223bb6e697646
Autor:
Yiin Ling, Bogdan Galusca, François‐Pierre Martin, Simona Bartova, Jérôme Carayol, Sofia Moco, Jacques Epelbaum, Dominique Grouselle, Yves Boirie, Christophe Montaurier, Joyceline Cuenco, James S. Minnion, Thierry Thomas, Sylvie Mure, Jörg Hager, Bruno Estour, Nele Gheldof, Natacha Germain
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 5, Pp 1187-1199 (2020)
Abstract Background Constitutional thinness (CT), a non‐malnourished underweight state with no eating disorders, is characterized by weight gain resistance to high fat diet. Data issued from muscle biopsies suggested blunted anabolic mechanisms in
Externí odkaz:
https://doaj.org/article/654e5a5d3f1e4b7b96b2ce309ce53831
Autor:
Armand Valsesia, Anirikh Chakrabarti, Jörg Hager, Dominique Langin, Wim H. M. Saris, Arne Astrup, Ellen E. Blaak, Nathalie Viguerie, Mojgan Masoodi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Weight loss aims to improve glycemic control in obese but strong variability is observed. Using a multi-omics approach, we investigated differences between 174 responders and 201 non-responders, that had lost >8% body weight following a low-
Externí odkaz:
https://doaj.org/article/b17731f6b55c46028452475f12f8184d
Autor:
Armand Valsesia, Qiao-Ping Wang, Nele Gheldof, Jérôme Carayol, Hélène Ruffieux, Teleri Clark, Victoria Shenton, Lisa J. Oyston, Gregory Lefebvre, Sylviane Metairon, Christian Chabert, Ondine Walter, Polina Mironova, Paulina Lau, Patrick Descombes, Nathalie Viguerie, Dominique Langin, Mary-Ellen Harper, Arne Astrup, Wim H. Saris, Robert Dent, Greg G. Neely, Jörg Hager
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Individuals show large variability in their capacity to lose weight and maintain this weight. Here, the authors perform GWAS in two weight loss intervention cohorts and identify two genetic loci associated with weight loss that are taken forward for
Externí odkaz:
https://doaj.org/article/69e3b05bacbb4d4db475ac38f90a9bda
Autor:
Hélène Ruffieux, Jérôme Carayol, Radu Popescu, Mary-Ellen Harper, Robert Dent, Wim H M Saris, Arne Astrup, Jörg Hager, Anthony C Davison, Armand Valsesia
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 6, p e1007882 (2020)
Molecular quantitative trait locus (QTL) analyses are increasingly popular to explore the genetic architecture of complex traits, but existing studies do not leverage shared regulatory patterns and suffer from a large multiplicity burden, which hampe
Externí odkaz:
https://doaj.org/article/8fb0cb05d4a441a397fbd8bd462d22f2
Autor:
Anne Lundby Hess, Jérôme Carayol, Trine Blædel, Jörg Hager, Alessandro Di Cara, Arne Astrup, Wim H. M. Saris, Lesli Hingstrup Larsen, Armand Valsesia
Publikováno v:
Genes & Nutrition, Vol 13, Iss 1, Pp 1-12 (2018)
Abstract Background Angiopoietin-like protein 3 (ANGPTL3), a liver-derived protein, plays an important role in the lipid and lipoprotein metabolism. Using data available from the DiOGenes study, we assessed the link with clinical improvements (weight
Externí odkaz:
https://doaj.org/article/3f7fb88a2638450ea37e83a4ea90c024
Autor:
Jérôme Carayol, Christian Chabert, Alessandro Di Cara, Claudia Armenise, Gregory Lefebvre, Dominique Langin, Nathalie Viguerie, Sylviane Metairon, Wim H. M. Saris, Arne Astrup, Patrick Descombes, Armand Valsesia, Jörg Hager
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Although many genetic variants are known for obesity, their function remains largely unknown. Here, in a weight-loss intervention cohort, the authors identify protein quantitative trait loci associated with BMI at baseline and after weight loss and f
Externí odkaz:
https://doaj.org/article/5a5fba936b994740abf88acab0a29fef
Publikováno v:
Frontiers in Nutrition, Vol 5 (2018)
Aim of Study: The use of weighed food diaries in nutritional studies provides a powerful method to quantify food and nutrient intakes. Yet, mapping these records onto food composition tables (FCTs) is a challenging, time-consuming and error-prone pro
Externí odkaz:
https://doaj.org/article/7f0c2c0851824dbfa6686d58a1b790f0
Autor:
Alice Matone, Marie-Pier Scott-Boyer, Jerome Carayol, Parastoo Fazelzadeh, Gregory Lefebvre, Armand Valsesia, Celine Charon, Jacques Vervoort, Arne Astrup, Wim H M Saris, Melissa Morine, Jörg Hager
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150495 (2016)
BACKGROUND AND SCOPE:Weight loss success is dependent on the ability to refrain from regaining the lost weight in time. This feature was shown to be largely variable among individuals, and these differences, with their underlying molecular processes,
Externí odkaz:
https://doaj.org/article/2091051d8b894b588adfad0dec2474f5
Publikováno v:
Frontiers in Genetics, Vol 4 (2013)
We review here the status of human type 2 diabetes studies from a genetic, epidemiological, and clinical (intervention) perspective. Most studies limit analyses to one or a few omic technologies providing data of components of physiological processes
Externí odkaz:
https://doaj.org/article/f5a7f08611994df1898bbc56a9f7da46