Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Jörg Grosshans"'
Autor:
Franziska Lehne, Thomas Pokrant, Sabnam Parbin, Gabriela Salinas, Jörg Großhans, Katja Rust, Jan Faix, Sven Bogdan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Calcium serves as an important second messenger in signal transduction to the actin cytoskeleton. Here, we identify EFhD2/Swip-1 as a calcium-dependent actin cross-linker promoting rapid reorganization of actin networks in epithelial wound closure.
Externí odkaz:
https://doaj.org/article/1c2db369029d45dbb7d14626ed48aa5c
Publikováno v:
Journal of Developmental Biology, Vol 11, Iss 4, p 40 (2023)
The presence of farnesylated proteins at the inner nuclear membrane (INM), such as the Lamins or Kugelkern in Drosophila, leads to specific changes in the nuclear morphology and accelerated ageing on the organismal level reminiscent of the Hutchinson
Externí odkaz:
https://doaj.org/article/d8892d16d324467f93b692a5e40ec09e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Dorsal closure is a prominent morphogenetic process during Drosophila embryogenesis, which involves two epithelial tissues, that is, the squamous amnioserosa and the columnar lateral epidermis. Non-muscle myosin II-driven constriction in the amnioser
Externí odkaz:
https://doaj.org/article/7ecbf9bc08b7419f90d13ef7ad003aa6
Autor:
Gabriele Selvaggio, Alexey Chizhik, Robert Nißler, llyas Kuhlemann, Daniel Meyer, Loan Vuong, Helen Preiß, Niklas Herrmann, Florian A. Mann, Zhiyi Lv, Tabea A. Oswald, Alexander Spreinat, Luise Erpenbeck, Jörg Großhans, Volker Karius, Andreas Janshoff, Juan Pablo Giraldo, Sebastian Kruss
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Near-infrared (NIR) fluorophores have attracted interest for bioimaging; yet availability, biocompatibility and application can be an issue. Here, the authors report on the development of Egyptian Blue nanosheets with high NIR fluorescence and photos
Externí odkaz:
https://doaj.org/article/dd2ee372071f4b35a772a96ad2f7e729
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3583-3593 (2019)
Protein phosphatase V (PpV) encodes the Drosophila homolog of the evolutionarily conserved Protein Phosphatase 6 (PP6). The physiological and developmental functions of PpV/PP6 have not been well characterized due to lack of a genetically defined mut
Externí odkaz:
https://doaj.org/article/20c4a94d3e834312b2eacffd65c680b5
Autor:
Deqing Kong, Jörg Großhans
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Planar cell polarity and anisotropic cell behavior play critical roles in large-scale epithelial morphogenesis, homeostasis, wound repair, and regeneration. Cell–Cell communication and mechano-transduction in the second to minute scale mediated by
Externí odkaz:
https://doaj.org/article/8e5610c89d6e41bcb2d3326b44369a82
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008735 (2020)
The protein phosphatase Cdc25 is a key regulator of the cell cycle by activating Cdk-cyclin complexes. Cdc25 is regulated by its expression levels and post-translational mechanisms. In early Drosophila embryogenesis, Cdc25/Twine drives the fast and s
Externí odkaz:
https://doaj.org/article/8c7cd75da18444afbc9b656c8277b372
Autor:
Shuling Yan, Jörg Großhans
Publikováno v:
Fly, Vol 12, Iss 3-4, Pp 191-198 (2018)
In this extra view, we comment on our recent work concerning the mRNA localization of the gene slow as molasses (slam). slam is a gene essential for the polarized invagination of the plasma membrane and separation of basal and lateral cortical domain
Externí odkaz:
https://doaj.org/article/214e91430e1b40fabf4d85aed8ca1968
Publikováno v:
Cells, Vol 10, Iss 9, p 2280 (2021)
Mechanosensitive ion channels mediate the neuronal sensation of mechanical signals such as sound, touch, and pain. Recent studies point to a function of these channel proteins in cell types and tissues in addition to the nervous system, such as epith
Externí odkaz:
https://doaj.org/article/ae26a86004c84f4782f4a90b8cdbe6b7
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 7, Pp 2305-2314 (2017)
Many metabolic enzymes are evolutionarily highly conserved and serve a central function in the catabolism and anabolism of cells. The serine hydroxymethyl transferase (SHMT) catalyzing the conversion of serine and glycine and vice versa feeds into te
Externí odkaz:
https://doaj.org/article/d057692ae5bc47d3a69e3771a2b72276