Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jörg Grigull"'
Autor:
Amira Moustafa, Sara Hashemi, Gurnoor Brar, Jörg Grigull, Siemon H. S. Ng, Declan Williams, Gerold Schmitt-Ulms, John C. McDermott
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-16 (2023)
Abstract Transcriptional regulators encoded by the Myocyte Enhancer Factor 2 (MEF2) gene family play a fundamental role in cardiac development, homeostasis and pathology. Previous studies indicate that MEF2A protein-protein interactions serve as a ne
Externí odkaz:
https://doaj.org/article/b0c052b01d944657a85525e0e060bb77
Autor:
Farnaz Mansouri-Noori, Andreas Pircher, Danielle Bilodeau, Lidia Siniavskaia, Jörg Grigull, Olivia S. Rissland, Mark A. Bayfield
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113226- (2023)
Summary: Messenger RNAs (mRNAs) in higher eukaryotes that encode proteins important for the assembly of the translational apparatus (e.g., ribosomal proteins) often harbor a pyrimidine-rich motif at the extreme 5′ end known as a 5′ terminal oligo
Externí odkaz:
https://doaj.org/article/24ab6f9c7cd04ee4847d6c7bacf5e1ca
Publikováno v:
PLoS Pathogens, Vol 9, Iss 5, p e1003363 (2013)
The genomes of plus-strand RNA viruses contain many regulatory sequences and structures that direct different viral processes. The traditional view of these RNA elements are as local structures present in non-coding regions. However, this view is cha
Externí odkaz:
https://doaj.org/article/0741e321a8074e4e8eed6a9ff8729941
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Pannexin 1 (Panx1) forms ATP-permeable membrane channels that play roles in the nervous system. The analysis of roles in both standard and pathological conditions benefits from a model organism with rapid development and early onset of behaviors. Suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400586ae6d5ee7134f6fd609cc8d3b35
http://link.springer.com/article/10.1038/s41598-020-66378-y
http://link.springer.com/article/10.1038/s41598-020-66378-y
Autor:
John C. McDermott, Jianzhong Zhao, Jörg Grigull, Stephanie W. Tobin, Sara Hashemi, Keith Dadson, K. Ebrahimian, Subat Turdi, Gary Sweeney
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Myocyte Enhancer Factor 2 (MEF2) mediates cardiac remodelling in heart failure (HF) and is also a target of β-adrenergic signalling, a front-line treatment for HF. We identified global gene transcription networks involved in HF with and without β-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::476cb2548ab5387f53811cc1dfa260b7
https://pubmed.ncbi.nlm.nih.gov/28667250
https://pubmed.ncbi.nlm.nih.gov/28667250
Autor:
R. John D'a. Honey, Kenneth T. Pace, George M. Yousef, Eman Fatoohi, Youssef M. Youssef, Jörg Grigull, Robert Stewart, Georg A. Bjarnason, Andrew H. Girgis, Tian Tian Bao, Maria Diamandis, Maged Metias, Nicole M.A. White
Publikováno v:
Journal of Urology. 186:1077-1083
Renal cell carcinoma is the most common neoplasm of the adult kidney. Currently to our knowledge there are no biomarkers for diagnostic, prognostic or predictive applications for renal cell carcinoma. miRNAs are nonprotein coding RNAs that negatively
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec51d2fd582cd735890bf5a894f67098
https://doi.org/10.1016/j.juro.2011.04.110
https://doi.org/10.1016/j.juro.2011.04.110
Autor:
Salvador Mejia-Guerrero, Jörg Grigull, Christina Samy, Youssef M. Youssef, Andrew Evans, Nicole M.A. White, Adriana Krizova, George M. Yousef
Publikováno v:
European Urology. 59:721-730
Background Renal cell carcinoma (RCC) encompasses different histologic subtypes. Distinguishing between the subtypes is usually made by morphologic assessment, which is not always accurate. Objective Our aim was to identify microRNA (miRNA) signature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2726a14cfd748d424ef86b08ce25cd8a
https://doi.org/10.1016/j.eururo.2011.01.004
https://doi.org/10.1016/j.eururo.2011.01.004
Autor:
Qiang Pan-Hammarström, Mani Larijani, Bhargavi Duvvuri, Gillian E. Wu, Alberto Martin, Venkata R. Duvvuri, Jörg Grigull
Publikováno v:
Immunogenetics
Pathogenic common variable immunodeficiency diseases (CVID) are genetic, usually inherited diseases for which a limited number of genetic defects have been implicated. As CVID presents with a wide range of clinical characteristics, there are likely d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27522c302605748d047ac20750f09e42
https://doi.org/10.1007/s00251-010-0483-7
https://doi.org/10.1007/s00251-010-0483-7
Autor:
Terence J. Colgan, K. W. Michael Siu, Leroi V. DeSouza, Valerie Dube, Shaun Ghanny, Alexander D. Romaschin,‖,⊥ and, Jörg Grigull
Publikováno v:
Journal of Proteome Research. 6:2648-2655
Verification of candidate protein biomarkers is a necessary step in moving from the initial discovery to application. Here, we report results of a verification exercise involving six candidate endometrial cancer biomarkers previously discovered using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fda4b831a17ac29da5663b155850d3d
https://doi.org/10.1021/pr070087o
https://doi.org/10.1021/pr070087o
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
There exists a remarkable evolutionary breadth of telomerase holoenzyme components among eukaryotes. Here the authors report that the fission yeast methyl phosphate capping enzyme Bin3/Bmc1 regulates telomerase activity by promoting holoenzyme format
Externí odkaz:
https://doaj.org/article/1a61feb1ffbf4f1f8a3234e916b3803b