Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jörg Deerberg"'
Publikováno v:
Tetrahedron. 65:6635-6641
The sector comprising C24–C34 of FK-506 containing five of the stereogenic centers in this macrolide was synthesized from (−)-quinic acid. Aldol coupling of the C24–C34 unit with a methyl ketone representing C20–C23 of FK-506 proceeded with c
Autor:
Trevor Laird, Jaan A. Pesti, Ahmed F. Abdel-Magid, Daniel Levin, Tony Y. Zhang, Sean P. Lapekas, Thomas Archibald, Stephen M. Stefanick, Ryo Sugiyama, Toru Yamano, Joerg Deerberg, Stefan Abele, Gunther Schmidt, Jacques-Alexis Funel, Mischa Schwaninger, Sven Wagner, Noel A. Hamill, Mark E. Howells, James H. Simpson, Atul S. Kotnis, Rajendra P. Deshpande, David J. Kacsur, Jason Hamm, Gus Kodersha, William Merkl, Daniel Domina, Steve Y. Wang, Nicholas A. Straessler, Louis F. Cannizzo, Michael W. Lesley, Oliver R. Thiel, John R. Huckins, Derek B. Brown, Eric A. Bercot, John T. Colyer, Bobby Riahi, Rob R. Milburn, Steve M. Shaw, Joe Tomaskevitch, David J. Ager, Ayman Allian, Bryan Li, Steven Guinness, L. Mleczko, Dongbo Zhao, Sripathy Venkatraman, Scott Tweedie, Mark McLaws, David Lathbury
Publikováno v:
ChemInform. 25
The piperidine alkaloid (–)-allosedamine (1) has been synthesized, in 21% overall yield, in nine steps starting from the formyl-ester 4. The synthesis features the reaction cascade 7 3 2, involving asymmetric electrophilic enolate hydroxyamination,
Autor:
Jörg Deerberg, James D. White
Publikováno v:
ChemInform. 29
The tin(II)-mediated reaction of α-alkoxythiolketene acetals 3a–d with trans-2-methylbut-2-enal and aldehyde 10 was found to give enhanced reactivity and high anti selectivity in the glycolate product when an α-benzyloxy substituent was present i
Publikováno v:
Helvetica Chimica Acta, Vol. 75, No 6 (1992) pp. 1965-1978
Successive treatment of N-acylsultams 3 with sodium hexamethyldisilazide, 1-chloro-1-nitrosocyclohexane (1), and aq. HCl gave diastereoisomerically pure, crystalline N-hydroxyamino-acid derivatives 5. These were converted into various amino acids 7,
Diastereo- and Enantiocontrolled Synthesis of (-)-Allosedamine via Cycloaddition of a Chiral Nitrone
Publikováno v:
Helvetica Chimica Acta, Vol. 77, No 2 (1994) pp. 554-560
The piperidine alkaloid (–)-allosedamine (1) has been synthesized, in 21% overall yield, in nine steps starting from the formyl-ester 4. The synthesis features the reaction cascade 7 → 3 → 2, involving asymmetric electrophilic enolate hydroxyam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b63fa71b86f8a1cf45b8a09d3b28e4
https://archive-ouverte.unige.ch/unige:151918
https://archive-ouverte.unige.ch/unige:151918
Autor:
Jörg Deerberg, James D. White
Publikováno v:
Chemical Communications. :1919
The tin(II)-mediated reaction of α-alkoxythiolketene acetals 3a–d with trans-2-methylbut-2-enal and aldehyde 10 was found to give enhanced reactivity and high anti selectivity in the glycolate product when an α-benzyloxy substituent was present i