Zobrazeno 1 - 10
of 319
pro vyhledávání: '"Jörg D. Hoheisel"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/7343c9f1134f48169338dfd19bac6887
Autor:
Katrin Hufnagel, Anahita Fathi, Nadine Stroh, Marco Klein, Florian Skwirblies, Ramy Girgis, Christine Dahlke, Jörg D. Hoheisel, Camille Lowy, Ronny Schmidt, Anne Griesbeck, Uta Merle, Marylyn M. Addo, Christoph Schröder
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-13 (2023)
Abstract Background The clinical course of COVID-19 patients ranges from asymptomatic infection, via mild and moderate illness, to severe disease and even fatal outcome. Biomarkers which enable an early prediction of the severity of COVID-19 progress
Externí odkaz:
https://doaj.org/article/a7d8b214bf0e427a9a9595f6ab093930
Autor:
Abdel Jelil Njouendou, Tibor Szarvas, Arnol Auvaker Zebaze Tiofack, Rovaldo Nguims Kenfack, Pamela Derliche Tonouo, Sidonie Noa Ananga, Esther H. M. Dina Bell, Gustave Simo, Jörg D. Hoheisel, Jens T. Siveke, Smiths S. Lueong
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background Inflammation is undoubtedly a hallmark of cancer development. Its maintenance within tumors and the consequences on disease aggressiveness are insufficiently understood. Methods Data of 27 tumor entities (about 5000 samples) were
Externí odkaz:
https://doaj.org/article/c4c04dc7508e4c02a1013c66e211ba35
Autor:
Irina Heid, Corinna Münch, Sinan Karakaya, Smiths S. Lueong, Alina M. Winkelkotte, Sven T. Liffers, Laura Godfrey, Phyllis F. Y. Cheung, Konstantinos Savvatakis, Geoffrey J. Topping, Florian Englert, Lukas Kritzner, Martin Grashei, Andrea Tannapfel, Richard Viebahn, Heiner Wolters, Waldemar Uhl, Deepak Vangala, Esther M. M. Smeets, Erik H. J. G. Aarntzen, Daniel Rauh, Wilko Weichert, Jörg D. Hoheisel, Stephan A. Hahn, Franz Schilling, Rickmer Braren, Marija Trajkovic-Arsic, Jens T. Siveke
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) lacks effective treatment options beyond chemotherapy. Although molecular subtypes such as classical and QM (quasi-mesenchymal)/basal-like with transcriptome-based distinct signatures have b
Externí odkaz:
https://doaj.org/article/bde08f1443834615a3f9cb25e23e0e2b
Autor:
Beiping Miao, Chaoyang Zhang, Nadine Stroh, Lukas Brenner, Katrin Hufnagel, Jörg D. Hoheisel, Obul Reddy Bandapalli
Publikováno v:
Cancer Communications, Vol 41, Iss 12, Pp 1423-1426 (2021)
Externí odkaz:
https://doaj.org/article/0e652feca0f84eb99825fe4fb580a751
MicroRNAs in blood act as biomarkers of colorectal cancer and indicate potential therapeutic targets
Autor:
Axel Stang, Hauke Weilert, Michael J. Lipp, Karl J. Oldhafer, Jörg D. Hoheisel, Chaoyang Zhang, Andrea S. Bauer
Publikováno v:
Molecular Oncology, Vol 15, Iss 9, Pp 2480-2490 (2021)
Association studies have linked alterations of blood‐derived microRNAs (miRNAs) with colorectal cancer (CRC). Here, we performed a microarray‐based comparison of the profiles of 2549 miRNAs in 80 blood samples from healthy donors and patients wit
Externí odkaz:
https://doaj.org/article/6bfac6e491c54bf2a7c646560ecb7729
Autor:
Mehdi Manoochehri, Yenan Wu, Nathalia A. Giese, Oliver Strobel, Stefanie Kutschmann, Florian Haller, Jörg D. Hoheisel, Evgeny A. Moskalev, Thilo Hackert, Andrea S. Bauer
Publikováno v:
Molecular Oncology, Vol 14, Iss 6, Pp 1252-1267 (2020)
Aberrant DNA methylation is often involved in carcinogenesis. Our initial goal was to identify DNA methylation biomarkers associated with pancreatic cancer. A genomewide methylation study was performed on DNA from pancreatic ductal adenocarcinoma (PD
Externí odkaz:
https://doaj.org/article/efee1bc52876402da2907cd05b04b8c6
Autor:
Esmaeel Babaeenezhad, Fakhraddin Naghibalhossaini, Masoumeh Rajabibazl, Zohreh Jangravi, Forouzan Hadipour Moradi, Mohammad Davood Fattahi, Jörg D. Hoheisel, Mostafa Moradi Sarabi, Soroosh Shahryarhesami
Publikováno v:
Non-Coding RNA, Vol 8, Iss 5, p 67 (2022)
Digestive tract cancers represent a serious public health issue. In recent years, evidence has accumulated that microRNA miR-185 is implicated in the pathogenesis of this group of highly malignant tumors. Its expression variations correlate with clin
Externí odkaz:
https://doaj.org/article/972dbb55c0004dfbab56d0d6f900fb92
Autor:
Katrin Hufnagel, Smiths Lueong, Martina Willhauck-Fleckenstein, Agnes Hotz-Wagenblatt, Beiping Miao, Andrea Bauer, Angelika Michel, Julia Butt, Michael Pawlita, Jörg D. Hoheisel, Tim Waterboer
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Using Chlamydia trachomatis (Ct) as a complex model organism, we describe a method to generate bacterial whole-proteome microarrays using cell-free, on-chip protein expression. Expression constructs were generated by two successive PCRs dire
Externí odkaz:
https://doaj.org/article/6e5136bb68724a66a4edce0dbcc7a62e
Autor:
Nan Shen, Jun Du, Hui Zhou, Nan Chen, Yi Pan, Jörg D. Hoheisel, Zonghui Jiang, Ling Xiao, Yue Tao, Xi Mo
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Lung adenocarcinoma (LUAD) is one of the most common cancers and lethal diseases in the world. Recognition of the undetermined lung nodules at an early stage is useful for a favorable prognosis. However, there is no good method to identify the undete
Externí odkaz:
https://doaj.org/article/49452fc136c04ad6a7f92c1f551a8879