Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jörg D Schulzke"'
Autor:
Silke S Zakrzewski, Jan F Richter, Susanne M Krug, Britta Jebautzke, In-Fah M Lee, Juliane Rieger, Monika Sachtleben, Angelika Bondzio, Jörg D Schulzke, Michael Fromm, Dorothee Günzel
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79643 (2013)
Cell lines matching the source epithelium are indispensable for investigating porcine intestinal transport and barrier properties on a subcellular or molecular level and furthermore help to reduce animal usage. The porcine jejunal cell line IPEC-J2 i
Externí odkaz:
https://doaj.org/article/16ba4617e0394c8081afad0bee7a5681
Anti-diarrheal mechanism of the traditional remedy Uzara via reduction of active chloride secretion.
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18107 (2011)
BACKGROUND AND PURPOSE: The root extract of the African Uzara plant is used in traditional medicine as anti-diarrheal drug. It is known to act via inhibition of intestinal motility, but malabsorptive or antisecretory mechanisms are unknown yet. EXPER
Externí odkaz:
https://doaj.org/article/9736e4453a9a4d75bd11bf858fea3aa8
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Scope: Ellagitannins are polyphenols found in numerous fruits, nuts and seeds. The elagitannin punicalagin and its bioactive metabolites ellagic acid and urolithins are discussed to comprise a high potential for therapeutically or preventive medical
Externí odkaz:
https://doaj.org/article/b34af8f70a9f49a9b19751b016e97042
Autor:
Julian Friebel, Katina Schinnerling, Kathleen Weigt, Claudia Heldt, Anja Fromm, Christian Bojarski, Britta Siegmund, Hans-Jörg Epple, Judith Kikhney, Annette Moter, Thomas Schneider, Jörg D. Schulzke, Verena Moos, Michael Schumann
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6197
Background: Tropheryma whipplei (TW) can cause different pathologies, e.g., Whipple’s disease and transient gastroenteritis. The mechanism by which the bacteria pass the intestinal epithelial barrier, and the mechanism of TW-induced gastroenteritis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fe43bb6b9b466b2b2bc474852363b9
Autor:
Franziska Weiß, David Holthaus, Martin Kraft, Christian Klotz, Martina Schneemann, Jörg D. Schulzke, Susanne M. Krug
Publikováno v:
Annals of the New York Academy of SciencesREFERENCES. 1515(1)
Usually, duodenal barriers are investigated using intestinal cell lines like Caco-2, which in contrast to native tissue are limited in cell-type representation. Organoids can consist of all intestinal cell types and are supposed to better reflect the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e803f5419aca9ae16b08ff9e3020ab96
https://pubmed.ncbi.nlm.nih.gov/35666953
https://pubmed.ncbi.nlm.nih.gov/35666953
Autor:
Jörg D. Schulzke, Michael Fromm
Publikováno v:
Ion Transport Across Epithelial Tissues and Disease ISBN: 9783030553098
The human intestinal mucosa is lined by a single layer of epithelial cells covering a complexly folded area of up to 200 m2. Regarding transport, this epithelium fulfills two contrasting functions: (1) absorption and secretion of ions, enzymes, nutri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1363c573c7da76f03b3aa2beb710a39
https://doi.org/10.1007/978-3-030-55310-4_3
https://doi.org/10.1007/978-3-030-55310-4_3
Autor:
Eric A.F. van Tol, Nina A. Hering, Gabriele Gross, Susanne M. Krug, Jörg D. Schulzke, Stephanie Wiegand, Julia Luettig, Rita Rosenthal
Publikováno v:
Annals of the New York Academy of Sciences. 1405:177-188
The iron-binding glycoprotein lactoferrin (LF) is naturally present in human breast milk. Several studies suggest that LF contributes to infant health and development owing to a variety of protective effects, including antimicrobial and anti-inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::585711f1519bea1890035c6cb0522098
https://doi.org/10.1111/nyas.13405
https://doi.org/10.1111/nyas.13405
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 22
Volume 20
Issue 22
In epithelia, large amounts of water pass by transcellular and paracellular pathways, driven by the osmotic gradient built up by the movement of solutes. The transcellular pathway has been molecularly characterized by the discovery of aquaporin membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fee2c1fde1da6a3415e44ab5b41385
Autor:
Aileen Harrer, Nicole Tegtmeyer, Urszula Zarzecka, Manja Boehm, Roland Bücker, Steffen Backert, Heinrich Sticht, Jörg D. Schulzke
Publikováno v:
Gut Pathogens
Gut Pathogens, Vol 11, Iss 1, Pp 1-16 (2019)
Gut Pathogens, Vol 11, Iss 1, Pp 1-16 (2019)
Campylobacter jejuni secretes HtrA (high temperature requirement protein A), a serine protease that is involved in virulence. Here, we investigated the interaction of HtrA with the host protein occludin, a tight junction strand component. Immunofluor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fa34e88f9c6408a2645ff025c755d6
http://europepmc.org/articles/PMC6373145
http://europepmc.org/articles/PMC6373145
Publikováno v:
Molecular Nutrition & Food Research. 60:2576-2586
cope Anti-inflammatory properties of the ginger-derived pungent component 6-shogaol (6-SG) have been studied intensively in recent years. Purpose of this study was to characterize the influence of 6-SG on inflammation-related intestinal barrier dysfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e15efa9d2ea0054e1abc1219c4146fe
https://doi.org/10.1002/mnfr.201600274
https://doi.org/10.1002/mnfr.201600274