Výsledky vyhledávání - "Jörg Blankenstein"

An Improved, Versatile, and Easily Scalable Synthesis of Sphingomyelins: Application to Stable Isotope Labeling

Autor: Franck Le Strat, Sébastien Roy, Nicolas Philippe, Jörg Blankenstein, Serge Pérard

Publikováno v: Synthesis. 52:2106-2110

With a view to make conveniently labeled mass spectrometry standards available, a set of deuterated sphingomyelins were prepared by a new expedient, flexible, robust, scalable, and high-yielding synthetic scheme starting from 2-azido-3-O-benzoylsphin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0158ef818247cdcf0a17cd44bd263c4
https://doi.org/10.1055/s-0039-1690863

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Cabazitaxel is more active than first-generation taxanes in ABCB1(+) cell lines due to its reduced affinity for P-glycoprotein

Autor: Diego A. Gianolio, Volker Derdau, Nicolas Philippe, George E. Duran, Jens Atzrodt, Dietmar Weitz, Jörg Blankenstein, Dorothée Semiond, Sandrine Mace, Branimir I. Sikic

Publikováno v: Cancer Chemotherapy and Pharmacology. 81:1095-1103

The primary aim of this study was to determine cabazitaxel’s affinity for the ABCB1/P-glycoprotein (P-gp) transporter compared to first-generation taxanes. We determined the kinetics of drug accumulation and retention using [14C]-labeled taxanes in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e273176e97a4fbb732eb46918490591a
https://doi.org/10.1007/s00280-018-3572-1

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Biological characterization of rodent and human vasopressin V1b receptors using SSR-149415, a nonpeptide V1b receptor ligand

Autor: John Allen, Maria A. Ventura, Jörg Blankenstein, Jean Wagnon, Brigitte Pouzet, Claudine Serradeil-Le Gal, Danièle Raufaste, Marc Pascal, Sylvain Derick

Publikováno v: American journal of physiology. Regulatory, integrative and comparative physiology. 293(2)

[3H]SSR-149415 is the first tritiated nonpeptide vasopressin V1breceptor (V1bR) antagonist ligand. It was used for studying rodent (mouse, rat, hamster) and human V1bR from native or recombinant origin. Moreover, a close comparison between the human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e626a81f3863a940afd12fc6196278
https://pubmed.ncbi.nlm.nih.gov/17522130

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Iridium-Catalyzed Enantioselective Hydrogenation of Olefins

Autor: Steven McIntyre, Andreas Pfaltz, Frederik Menges, Sebastian P. Smidt, Robert Hilgraf, Jörg Blankenstein, Bettina Wüstenberg, Marc Schönleber, Nicole Zimmermann, Esther Hörmann

Publikováno v: ChemInform. 34

Cationic iridium complexes with chiral P,N-ligands and tetrakis[3,5-(trifluoromethyl)phenyl]borate (BArF) as the counterion are efficient homogeneous catalysts for the enantioselective hydrogenation of olefins. The complexes are readily prepared, air

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e19afaafe53efa9a3a88ad3b10002c1
https://doi.org/10.1002/chin.200318253

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A New Class of Modular Phosphinite-Oxazoline Ligands: Ir-Catalyzed Enantioselective Hydrogenation of Alkenes We thank Dr. Martin Studer and Dr. Benoît Pugin (Solvias AG, Basel) for fruitful discussions, and Prof. Kevin Burgess (Texas AM University) for preprints of related unpublished work. Financial support by the Swiss National Science Foundation is gratefully acknowledged

Autor: Jörg, Blankenstein, Andreas, Pfaltz

Publikováno v: Angewandte Chemie (International ed. in English). 40(23)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::98c691412a1b08df9db916db06c51366
https://pubmed.ncbi.nlm.nih.gov/12404440

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A New Class of Modular Phosphinite–Oxazoline Ligands: Ir-Catalyzed Enantioselective Hydrogenation of Alkenes We thank Dr. Martin Studer and Dr. Benoît Pugin (Solvias AG, Basel) for fruitful discussions, and Prof. Kevin Burgess (Texas A&M University) for preprints of related unpublished work. Financial support by the Swiss National Science Foundation is gratefully acknowledged

Autor: Andreas Pfaltz, Jörg Blankenstein

Publikováno v: Angewandte Chemie International Edition. 40:4445

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43c46e48112ddea0371c3ca4a4b22a6a
https://doi.org/10.1002/1521-3773(20011203)40:23<4445::aid-anie4445>3.0.co

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Akademický článek

Conformation-Directed Macrocyclization Reactions.

Autor: Jörg Blankenstein, Jieping Zhu

Publikováno v: European Journal of Organic Chemistry; May2005, Vol. 2005 Issue 10, p1949-1964, 16p

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Akademický článek

PCSK9 Modulates the Secretion But Not the Cellular Uptake of Lipoprotein(a) Ex Vivo

Autor: Elise F. Villard, PhD, Aurélie Thedrez, PhD, Jorg Blankenstein, PhD, Mikaël Croyal, BSc, Thi-Thu-Trang Tran, PhD, Bruno Poirier, PhD, Jean-Christophe Le Bail, PhD, Stéphane Illiano, PhD, Estelle Nobécourt, MD, PhD, Michel Krempf, MD, PhD, Dirk J. Blom, MD, PhD, A. David Marais, MD, Philip Janiak, PhD, Anthony J. Muslin, MD, PhD, Etienne Guillot, PhD, Gilles Lambert, PhD

Publikováno v: JACC: Basic to Translational Science, Vol 1, Iss 6, Pp 419-427 (2016)

To elucidate how the proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor alirocumab modulates lipoprotein(a) [Lp(a)] plasma levels, the authors performed a series of Lp(a) uptake studies in primary human hepatocytes and dermal fibroblasts

Externí odkaz: https://doaj.org/article/a2e8609f65714b7b9f3d883bea5a8386

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