Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jörg Blümel"'
The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By c
Autor:
Heidemarie Ratsch, Gerhard Stiens, Andrew Pickett, Dirk Dressler, Dorothea Sesardic, Manfred Liebsch, Irmela Ruhdel, Birgit Kegel, Andreas Luch, Peter D. Thornton, Gerd Bicker, Martin Vey, Catherine Milne, Sarah Adler, Hans Bigalke, Joan Fitzgerald, Heide Heuschen, Frank Gessler, Christopher Bishop, René Thürmer, Martin L. Stephens, Jörg Blümel, Horst Spielmann, Barbara Grune
Publikováno v:
Alternatives to Laboratory Animals. 38:315-330
An Expert Meeting on The Current Scientific and Legal Status of Alternative Methods to the LD50 Test for Botulinum Neurotoxin (BoNT) Potency Testing was organised by the Centre for Documentation and Evaluation of Alternatives to Animal Experiments (Z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef209315b1946b279a0fca5c256edca
https://doi.org/10.1177/026119291003800401
https://doi.org/10.1177/026119291003800401
Autor:
Louis Dubertret, Andrea Blotz, Jörg Blümel, Laurence Michel, H.J. Ahr, Hans-Werner Vohr, A. Moysan
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 58:46-53
Currently available test models for the differentiation of photoallergic and photoirritant reactions are extremely time consuming and the protocols are very heterogeneous. In vitro tests are of proven value in predicting irritant or toxic effects, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d57b54a1ad2d4d2e5ebc9afe616eadcb
https://doi.org/10.1016/s1011-1344(00)00097-x
https://doi.org/10.1016/s1011-1344(00)00097-x
Autor:
Nadine Krause, Jörg Blümel
Publikováno v:
High-Throughput Screening Methods in Toxicity Testing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb5545fd3abb5623ba70ecd73660e0e5
https://doi.org/10.1002/9781118538203.ch13
https://doi.org/10.1002/9781118538203.ch13
Publikováno v:
Drugs. 67(5)
Botulinum neurotoxin type A (BTX-A) weakens voluntary muscle strength and is an effective therapy for focal dystonia, including cervical dystonia (CD) and benign essential blepharospasm (BEB). It is also known to relieve hemifacial spasm and focal sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f5bc5c2b0057c380ada3bd3564bf11
https://pubmed.ncbi.nlm.nih.gov/17385940
https://pubmed.ncbi.nlm.nih.gov/17385940
Autor:
Jörg, Blümel
Publikováno v:
Krankenpflege Journal. 43(7-10)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17bee41bb6148a8c60d69b4ef5961991
https://pubmed.ncbi.nlm.nih.gov/16515326
https://pubmed.ncbi.nlm.nih.gov/16515326
Autor:
Jörg Blümel
Publikováno v:
Encyclopedia of Immunotoxicology ISBN: 9783642277863
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d365c15d5754d20ad9243a01d91b90
https://doi.org/10.1007/3-540-27806-0_202
https://doi.org/10.1007/3-540-27806-0_202
An integrated model for the differentiation of chemical-induced allergic and irritant skin reactions
Autor:
Jörg Blümel, Christiane von Schilling, Hans-Werner Vohr, Percy Lehmann, Hans-Christian Schuppe, Thomas Ruzicka, H.J. Ahr, Bernhard Homey
Publikováno v:
Toxicology and applied pharmacology. 153(1)
Contact and photocontact allergic as well as irritant and photoirritant skin reactions represent a major problem in clinical dermatology and during the development of new pharmaceuticals. Furthermore, there is a lack ofin vitroandin vivoassays that p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e09307791a696c237c4d944df18f11
https://pubmed.ncbi.nlm.nih.gov/9875302
https://pubmed.ncbi.nlm.nih.gov/9875302
Autor:
Huifang . Chen
Due to the phylogenetic relationship and close genetic and biological similarities with humans, non-human primates (NHP) are regularly used in biomedical and behavioural research. However, because of their highly developed cognitive abilities and soc
Autor:
Pablo Steinberg
Explores the benefits and limitations of the latest high-throughput screening methods With its expert coverage of high-throughput in vitro screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamlin