Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jörg Bartel"'
Autor:
Jörg Bartel, Jan Krumsiek, Katharina Schramm, Jerzy Adamski, Christian Gieger, Christian Herder, Maren Carstensen, Annette Peters, Wolfgang Rathmann, Michael Roden, Konstantin Strauch, Karsten Suhre, Gabi Kastenmüller, Holger Prokisch, Fabian J Theis
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005274 (2015)
Biological systems consist of multiple organizational levels all densely interacting with each other to ensure function and flexibility of the system. Simultaneous analysis of cross-sectional multi-omics data from large population studies is a powerf
Externí odkaz:
https://doaj.org/article/299284eed4214aedbfd470a31574970c
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 4, Iss 5 (2013)
Metabolomics is a relatively new high-throughput technology that aims at measuring all endogenous metabolites within a biological sample in an unbiased fashion. The resulting metabolic profiles may be regarded as functional signatures of the physiolo
Externí odkaz:
https://doaj.org/article/8ae3682e911a4170a944f93d05373ce8
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 4, Iss 5, p e201301009 (2013)
Metabolomics is a relatively new high-throughput technology that aims at measuring all endogenous metabolites within a biological sample in an unbiased fashion. The resulting metabolic profiles may be regarded as functional signatures of the physiolo
Externí odkaz:
https://doaj.org/article/0fdc3b6eb82a4e4a9907829c8145893f
Publikováno v:
Curr. Opin. Biotechnol. 39, 198-206 (2016)
Systems genetics is defined as the simultaneous assessment and analysis of multi-omics datasets. In the past few years, metabolomics has been established as a robust tool describing an important functional layer in this approach. The metabolome of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5b9419bd6a01b9e0c4503f1cc9db62
Autor:
Oliver Eickelberg, Fabian J. Theis, Korbinian Ballweg, Stefanie Günter, Jan Krumsiek, Jörg Bartel, Cornelia Prehn, Jerzy Adamski, Thomas M. Conlon, A. O. Yildirim, Silke Meiners
Publikováno v:
Clin. Sci. 130, 273-287 (2016)
Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, small airway remodelling and emphysema. Emphysema is the destruction of alveolar structures, leading to enlarged airspaces and reduced surface area impairing the abi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659effbdb8cc0c8413371c0f148933d6
https://doi.org/10.1042/cs20150438
https://doi.org/10.1042/cs20150438
Autor:
Ali Önder Yildirim, Fabian J. Theis, Oliver Eickelberg, Jan Krumsiek, Jörg Bartel, Julian Dorer, Martina Häckl, Thomas M. Conlon
Publikováno v:
Airway Cell Biology and Immunopathology.
COPD is characterized by chronic inflammation, small airway remodeling and emphysema and remains a major public health problem. Despite reduced symptomatic medication a curative therapy is still missing. We performed cross-omics integrated enrichment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::734ceef2be329e9d9651b6c4909b74a5
https://doi.org/10.1183/1393003.congress-2017.oa291
https://doi.org/10.1183/1393003.congress-2017.oa291
Autor:
Jerzy Adamski, Jörg Bartel, Thomas M. Conlon, Oliver Eickelberg, Ali Önder Yildirim, Fabian J. Theis, Jan Krumsiek, Cornelia Prehn
Publikováno v:
3.2 Airway Cell Biology and Immunopathology.
COPD, the third leading cause of death worldwide, is characterized by small airway remodeling, chronic bronchitis and emphysema, which is the destruction of alveolar structures impairing the ability for gaseous exchange. Metabolomics, a rapidly expan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286321123f019ab5d113a5625ce3ddf8
https://doi.org/10.1183/13993003.congress-2016.oa463
https://doi.org/10.1183/13993003.congress-2016.oa463
Autor:
Jan Krumsiek, Michael Roden, Jörg Bartel, Tim Kacprowski, Christa Meisinger, Katharina Schramm, Heiner Boeing, Pasi Soininen, Christian Gieger, Ute Nöthlings, Ferdinand Stückler, Barbara Thorand, Christian Herder, Gabi Kastenmüller, Melanie Waldenberger, Maren Carstensen, Thomas Illig, Wolfgang Rathmann, Jakob Linseisen, Susanne Vogt, Carolin Jourdan, Holger Prokisch, Karsten Suhre, Georg Homuth, Harald Grallert, Antti J. Kangas, Simone Wahl, Mika Ala-Korpela, Annette Peters, Fabian J. Theis
Publikováno v:
BMC medicine, 13: 48
BMC Medicine
BMC Med. 13:48 (2015)
BMC Medicine
BMC Med. 13:48 (2015)
Background Excess body weight is a major risk factor for cardiometabolic diseases. The complex molecular mechanisms of body weight change-induced metabolic perturbations are not fully understood. Specifically, in-depth molecular characterization of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289a00c42923beaa6b1198ac9088e2c2
https://doi.org/10.1186/s12916-015-0282-y
https://doi.org/10.1186/s12916-015-0282-y
Autor:
Christian Gieger, Jerzy Adamski, Michael Roden, Fabian J. Theis, Wolfgang Rathmann, Christian Herder, Annette Peters, Jan Krumsiek, Maren Carstensen, Konstantin Strauch, Gabi Kastenmüller, Holger Prokisch, Karsten Suhre, Katharina Schramm, Jörg Bartel
Publikováno v:
PLoS Genetics, 11(6):e1005274
PLoS Genet. 11:e1005274 (2015)
PLoS Genetics, Vol 11, Iss 6, p e1005274 (2015)
PLoS Genetics
PLoS Genet. 11:e1005274 (2015)
PLoS Genetics, Vol 11, Iss 6, p e1005274 (2015)
PLoS Genetics
Biological systems consist of multiple organizational levels all densely interacting with each other to ensure function and flexibility of the system. Simultaneous analysis of cross-sectional multi-omics data from large population studies is a powerf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c06b212c509dbf1b36606a620d5b47fd
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005274#sec023
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005274#sec023
Autor:
Harald Jungnickel, Maxie Rockstroh, Wolfgang Otto, Martin von Bergen, Sarah Potratz, Edith Willscher, Andreas Luch, Sven Baumann, Jörg Bartel, Janina M. Tomm, Fabian J. Theis, Jan Krumsiek
Publikováno v:
Journal of Integrated OMICS. 4
Although the activation of immune cells is the first and thereby pivotal step in the immunological cascade, the current knowledge about the details of this process is quite limited. Recent studies have shown that aromatic compounds, such as B[ a ]P,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a767caa51a21c3246799cda3480cab39
https://doi.org/10.5584/jiomics.v4i1.157
https://doi.org/10.5584/jiomics.v4i1.157