Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jörg Büscher"'
Autor:
Angela Castoldi, Lauar B. Monteiro, Nikki van Teijlingen Bakker, David E. Sanin, Nisha Rana, Mauro Corrado, Alanna M. Cameron, Fabian Hässler, Mai Matsushita, George Caputa, Ramon I. Klein Geltink, Jörg Büscher, Joy Edwards-Hicks, Erika L. Pearce, Edward J. Pearce
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
As macrophages switch to a proinflammatory gylcolytic state they start to generate triglyceride-rich lipid droplets, but what function these droplets have in this context is not clear. Here the authors show that this triglyceride synthesis is requisi
Externí odkaz:
https://doaj.org/article/e66368483cc344ee9854c2ede5bf41d5
Autor:
Mai Matsushita, Angela Castoldi, Edward J. Pearce, Mauro Corrado, Nisha Rana, George Caputa, Nikki van Teijlingen Bakker, Alanna M. Cameron, Jörg Büscher, Ramon I. Klein Geltink, Lauar B. Monteiro, Joy Edwards-Hicks, David E. Sanin, Fabian Hässler, Erika L. Pearce
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Foamy macrophages, which have prominent lipid droplets (LDs), are found in a variety of disease states. Toll-like receptor agonists drive triacylglycerol (TG)-rich LD development in macrophages. Here we explore the basis and significance of this proc
Autor:
Lauar de Brito Monteiro, Juliana Silveira Prodonoff, Cristhiane Favero de Aguiar, Felipe Correa-da-Silva, Angela Castoldi, Nikki van Teijlingen Bakker, Gustavo Gastão Davanzo, Bianca Castelucci, Jéssica Aparecida da Silva Pereira, Jonathan Curtis, Jörg Büscher, Larissa Menezes dos Reis, Gisele Castro, Guilherme Ribeiro, João Victor Virgílio-da-Silva, Douglas Adamoski, Sandra Martha Gomes Dias, Silvio Roberto Consonni, Jose Donato, Edward J. Pearce, Niels Olsen Saraiva Câmara, Pedro M. Moraes-Vieira
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Obesity is a major concern for global healthcare systems. Systemic low-grade inflammation in obesity is a major risk factor for insulin resistance. Leptin is an adipokine secreted by the adipose tissue that functions by controlling food intake, leadi
Autor:
Sebastian Halbach, Marina Kreutz, Joy Edwards-Hicks, Melanie Boerries, Justus Duyster, Jörg Büscher, Tobias Madl, Olaf Groß, Sandra Duquesne, David O’Sullivan, Eileen Haring, Wolfgang Melchinger, Gesa Richter, Petya Apostolova, Tilman Brummer, Michael Lübbert, Erika L. Pearce, Franziska M. Uhl, Barbara Sauer, Sophia Chen, Bruce R. Blazar, Geoffroy Andrieux, Robert Zeiser, Annette Schmitt-Graeff, Khalid Shoumariyeh
Publikováno v:
Sci Transl Med
Science translational medicine : integrating medicine and science / American Association for the Advancement of Science
Science translational medicine : integrating medicine and science / American Association for the Advancement of Science
Acute myeloid leukemia (AML) relapse after allogeneic hematopoietic cell transplantation (allo-HCT) has a dismal prognosis. We found that T cells of patients relapsing with AML after allo-HCT exhibited reduced glycolysis and interferon-γ production.
Autor:
Katharina Schönberger, Nadine Obier, Mari Carmen Romero-Mulero, Pierre Cauchy, Julian mess, Polina Pavlovich, Yu Wei Zhang, Michael Mitterer, Jasmin Rettkowski, Karin Jäcklein, Curtis Jonathan, Jörg Büscher, Erika L. Pearce, Nina Cabezas-Wallscheid
Publikováno v:
Experimental Hematology. 100:S101
Autor:
Jörg Büscher, Sophia Chen, Robert Zeiser, Michael D. Buck, Khalid Shoumariyeh, David O’Sullivan, Jürgen Finke, Melanie Börries, Franziska M. Uhl, Gesa Richter, Dietmar Pfeifer, Hartmut Bertz, Tobias Madl, Erika L. Pearce, Justus Duyster
Publikováno v:
Blood. 132:3328-3328
Allogeneic hematopoietic cell transplantation (allo-HCT) is the treatment strategy of choice for the majority of patients with acute myeloid leukemia (AML). However, about 40% of patients relapse, which is associated with a poor prognosis. Donor lymp