Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jörg Bäurle"'
Publikováno v:
Brain Pathol
Elevated concentrations of Zn, Cu and Fe, observed in biopsied or post‐mortem tissue from diseased human brains, have often been considered as some of the major factors in the etiology of excitotoxic neuronal death but without any direct evidence f
Autor:
Helena Svecova, Hana Chaloupkova, Daniel Seifert, Miroslav Fiser, Veronika Kleinova, Jörg Bäurle, Karel Kranda, Vlastimil Král
Publikováno v:
Applied Radiation and Isotopes. 66:310-316
The monoclonal antibody TU-20 and its scFv fragment were radiolabeled with 125I in order to develop new imaging agents against the specific neuronal marker III β-tubulin. The reaction via chloramine-T using thiosulfate as a stopping reductant was de
Autor:
Jörg Bäurle, Mario Cabraja
Publikováno v:
The Journal of Comparative Neurology. 504:418-426
Bipolar neurons (BNs) in the vestibular ganglion (VG) connect vestibular hair cells with the central nervous system (CNS). Disturbed function and cell loss in central vestibular target areas or in the vestibular periphery involve BNs either retro- or
Publikováno v:
Acta Neuropathologica. 112:691-702
Apoptosis as well as autophagy have been implicated in the death of cerebellar Purkinje cells (PCs) in the Lurcher (Lc/+) mutant mouse and at least two different apoptotic pathways participate in the transsynaptic death of granule cells (GC) and infe
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 269:555-559
Our objective was to test the efficacy of neutron activation analysis (NAA) for monitoring trace elements in discrete brain regions of wild-type and mutant mice (weaver)with well-documented spatiotemporal patterns of neuronal loss in the cerebellum.
Autor:
Ursula Grüsser-Cornehls, Jörg Bäurle
Publikováno v:
Progress in Neurobiology. 63:489-540
Not later than two synapses after their arrival in the cerebellar cortex all excitatory afferent signals are subsequently transformed into inhibitory ones. Guaranteed by the exceedingly ordered and stereotyped synaptic arrangement of its cellular ele
Publikováno v:
Neuroscience Letters
The weaver mutation causes cell loss in the center of the substantia nigra, pars compacta. We compared the depression of γ-aminobutyric acid (GABA) A synaptic currents by the GABA B agonist R-baclofen in pars compacta neurons of weaver mice which we
Publikováno v:
The Journal of Comparative Neurology. 420:363-372
The distribution of cortical efferent connections to the vestibular nuclei was quantitatively analyzed by means of retrograde axonal transport of horseradish peroxidase, wheat germ agglutinin-horseradish peroxidase, and Fast Blue in rats. The tracer
Publikováno v:
The Journal of Comparative Neurology. 402:111-128
The subpopulation of primary vestibular afferents (PVA) displaying immunoreactivity for the calcium binding protein Calbindin D-28k (Calb) is constituted of particularly large bipolar neurons in the vestibular ganglion (VG) that innervate the central
Publikováno v:
The Journal of Neuroscience. 18:4001-4007
Weaver(wv) mice carry a point mutation in the pore region of a G-protein-gated inwardly rectifying K+channel subunit (Kir3.2).wvKir3.2 conducts inward currents that may cause the loss of neurons in the cerebellum and substantia nigra. Although Kir3.2