Zobrazeno 1 - 10
of 201
pro vyhledávání: '"Jörg Stypmann"'
Autor:
Matthias Rohrbeck, Verena Hoerr, Ilaria Piccini, Boris Greber, Jan Sebastian Schulte, Sara-Sophie Hübner, Elena Jeworutzki, Carsten Theiss, Veronika Matschke, Jörg Stypmann, Andreas Unger, Huyen Tran Ho, Paul Disse, Nathalie Strutz-Seebohm, Cornelius Faber, Frank Ulrich Müller, Stephan Ludwig, Ursula Rescher, Wolfgang A. Linke, Karin Klingel, Karin Busch, Stefan Peischard, Guiscard Seebohm
Publikováno v:
Cells, Vol 12, Iss 4, p 550 (2023)
Viral myocarditis is pathologically associated with RNA viruses such as coxsackievirus B3 (CVB3), or more recently, with SARS-CoV-2, but despite intensive research, clinically proven treatment is limited. Here, by use of a transgenic mouse strain (TG
Externí odkaz:
https://doaj.org/article/db7af84332ff43d5847796a3095ebeff
Autor:
Johanna K. Freundt, Gerrit Frommeyer, Tilmann Spieker, Fabian Wötzel, Jochen Schulze Grotthoff, Jörg Stypmann, Georg Hempel, Michael Schäfers, Andreas H. Jacobs, Lars Eckardt, Philipp S. Lange
Publikováno v:
BMC Pharmacology and Toxicology, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background The development of heart failure is accompanied by complex changes in cardiac electrophysiology and functional properties of cardiomyocytes and fibroblasts. Histone deacetylase (HDAC) inhibitors hold great promise for the pharmace
Externí odkaz:
https://doaj.org/article/7efda64f0274422f87b8bbf3dc46c0ac
Autor:
Alexander Grabner, Karla Schramm, Neerupma Silswal, Matt Hendrix, Christopher Yanucil, Brian Czaya, Saurav Singh, Myles Wolf, Sven Hermann, Jörg Stypmann, Giovana Seno Di Marco, Marcus Brand, Michael J. Wacker, Christian Faul
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Fibroblast growth factor (FGF) 23 is a phosphaturic hormone that directly targets cardiac myocytes via FGF receptor (FGFR) 4 thereby inducing hypertrophic myocyte growth and the development of left ventricular hypertrophy (LVH) in rodents. S
Externí odkaz:
https://doaj.org/article/cb4d0dfc6664400eb70380aa34adcde3
Autor:
Petra Keul, Marcel M. G. J. van Borren, Alexander Ghanem, Frank Ulrich Müller, Antonius Baartscheer, Arie O. Verkerk, Frank Stümpel, Jan Sebastian Schulte, Nazha Hamdani, Wolfgang A. Linke, Pieter van Loenen, Marek Matus, Wilhelm Schmitz, Jörg Stypmann, Klaus Tiemann, Jan‐Hindrik Ravesloot, Astrid E. Alewijnse, Sven Hermann, Léon J. A. Spijkers, Karl‐Heinz Hiller, Deron Herr, Gerd Heusch, Michael Schäfers, Stephan L. M. Peters, Jerold Chun, Bodo Levkau
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 5 (2016)
BackgroundSphingosine‐1‐phosphate plays vital roles in cardiomyocyte physiology, myocardial ischemia–reperfusion injury, and ischemic preconditioning. The function of the cardiomyocyte sphingosine‐1‐phosphate receptor 1 (S1P1) in vivo is un
Externí odkaz:
https://doaj.org/article/fbf5ff26565e41e1860b0d2d29621773
Autor:
Joachim Wistuba, Cristin Beumer, Ann-Sophie Warmeling, Reinhild Sandhowe-Klaverkamp, Jörg Stypmann, Michael Kuhlmann, Richard Holtmeier, Oliver S. Damm, Frank Tüttelmann, Jörg Gromoll
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Hypergonadotropic hypogonadism is a major feature of Klinefelter syndrome (KS), assumed to be caused by testicular hormone resistance. It was previously shown that intratesticular testosterone levels in vivo and Leydig cell function in vitro seem to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::690d53eb0b328ddb37045aacf2fa63ab
http://link.springer.com/article/10.1038/s41598-020-71377-0
http://link.springer.com/article/10.1038/s41598-020-71377-0
Autor:
Thomas Duning, Michael Deppe, Simon Keller, Hagen Schiffbauer, Jörg Stypmann, Matthias Böntert, Roland Schaefer, Peter Young
Publikováno v:
Case Reports in Neurology, Vol 1, Iss 1, Pp 33-40 (2009)
Fabry disease (FD) is an X-linked lysosomal storage disorder characterized by a deficient activity of the enzyme α-galactosidase A, resulting in a vasculopathic involvement of various organ systems, e.g. cerebral structures. Marked cerebral vasculop
Externí odkaz:
https://doaj.org/article/a737866e94014dcab40110f4ac06524e
Autor:
Christoph Knosalla, Hans B. Lehmkuhl, Jens Garbade, Christian Sieder, Stephan Hirt, Jörg Stypmann, Markus J. Barten, Uwe Schulz, Carola Grinninger, Andreas O. Doesch, Christoph Bara, Martina Porstner
Publikováno v:
American Journal of Transplantation. 19:3006-3017
In the 12-month, open-label MANDELA study, patients were randomized at month 6 after heart transplantation to (i) convert to calcineurin inhibitor (CNI)-free immunosuppression with everolimus (EVR), mycophenolic acid and steroids (CNI-free, n=71), or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::416d2f3edd8979378d4844c0d151b6bc
https://doi.org/10.1111/ajt.15361
https://doi.org/10.1111/ajt.15361
Autor:
Thomas Duning, Michael Deppe, Eva Brand, Jörg Stypmann, Charlotte Becht, Anna Heidbreder, Peter Young
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60304 (2013)
BACKGROUND: The exact underlying pathomechanism of central sleep apnea with Cheyne-Stokes respiration (CSA-CSR) is still unclear. Recent studies have demonstrated an association between cerebral white matter changes and CSA. A dysfunction of central
Externí odkaz:
https://doaj.org/article/b67bbc7595d14a06a14330097539ca0d
Autor:
Stephan W. Hirt, Christoph Bara, Markus J. Barten, Tobias Deuse, Andreas O. Doesch, Ingo Kaczmarek, Uwe Schulz, Jörg Stypmann, Assad Haneya, Hans B. Lehmkuhl
Publikováno v:
Journal of Transplantation, Vol 2013 (2013)
The evidence base relating to the use of everolimus in heart transplantation has expanded considerably in recent years, providing clinically relevant information regarding its use in clinical practice. Unless there are special considerations to take
Externí odkaz:
https://doaj.org/article/1778f3bc7fda49fcbe45dad40ac8c7a6
Autor:
Hartmut Schmidt, Constantin E. Uhlig, Jörg Stypmann, Matthias Schilling, Christoph Niemietz, Christoph Röcken
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 143:427-430
Transthyretin-related Familial Amyloid Polyneuropathy (ATTR Amyloidosis, former FAP, here called TTR-FAP) is a rare, progressive autosomal dominant inherited amyloid disease ending fatal within 5 – 15 years after final diagnosis. TTR-FAP is caused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def5ff05e8da42a21d0f28347922dec2
https://doi.org/10.1055/s-0043-123681
https://doi.org/10.1055/s-0043-123681