Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Jörg Fiedler"'
Autor:
Amelie Kuhn, Markus Huber-Lang, Sebastian Weckbach, Jana Riegger, Graciosa Q. Teixeira, Volker Rasche, Jörg Fiedler, Cornelia Neidlinger-Wilke, Rolf E. Brenner
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1692 (2024)
Previous studies indicate an implication of the terminal complement complex (TCC) in disc degeneration (DD). To investigate the functional role of TCC in trauma-induced DD in vivo, the model of endplate (EP) drilling was first applied in rabbits usin
Externí odkaz:
https://doaj.org/article/d75f8a054d524407b6710a36f5300518
Autor:
Hanna Tritschler, Konrad Fischer, Jochen Seissler, Jörg Fiedler, Rebecca Halbgebauer, Markus Huber-Lang, Angelika Schnieke, Rolf E. Brenner
Publikováno v:
Cells, Vol 10, Iss 8, p 2152 (2021)
Transplantation of xenogenic porcine chondrocytes could represent a future strategy for the treatment of human articular cartilage defects. Major obstacles are humoral and cellular rejection processes triggered by xenogenic epitopes like α-1,3-Gal a
Externí odkaz:
https://doaj.org/article/48f44517d73c4437822c6f56ca9ecaaa
Publikováno v:
Molecular Medicine, Vol 19, Iss 1, Pp 36-42 (2013)
Abstract Bone has a high capacity for self-renewal and repair. Prolonged local secretion of interleukin 1β (IL-1β), however, is known to be associated with severe bone loss and delayed fracture healing. Since induction of bone resorption by IL-1β
Externí odkaz:
https://doaj.org/article/c2265f65019b48bdaed07245bb844140
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116772 (2015)
Multipotent mesenchymal stromal cells (MSC) exert immune-modulatory effects and support tissue regeneration in various local trauma models. In case of a polytrauma, high amounts of danger-associated molecular patterns are released, leading to a syste
Externí odkaz:
https://doaj.org/article/1b135acd4a2c4f94aff2317a863d5496
Autor:
Markus Huber-Lang, Jörg Fiedler, Angelika Schnieke, Rolf E. Brenner, Rebecca Halbgebauer, Konrad Fischer, Jochen Seissler, Hanna Tritschler
Publikováno v:
Cells, Vol 10, Iss 2152, p 2152 (2021)
Cells
Volume 10
Issue 8
Cells
Volume 10
Issue 8
Transplantation of xenogenic porcine chondrocytes could represent a future strategy for the treatment of human articular cartilage defects. Major obstacles are humoral and cellular rejection processes triggered by xenogenic epitopes like α-1,3-Gal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d48ec7e5742c411887ce3ad49e8ddba
Autor:
Annika Kasten, Tamara Naser, Kristina Brüllhoff, Jörg Fiedler, Petra Müller, Martin Möller, Joachim Rychly, Jürgen Groll, Rolf E Brenner
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109411 (2014)
Designing of implant surfaces using a suitable ligand for cell adhesion to stimulate specific biological responses of stem cells will boost the application of regenerative implants. For example, materials that facilitate rapid and guided migration of
Externí odkaz:
https://doaj.org/article/111d8ed648ab4e55ae7f8a5cdfd6446a
Autor:
Julia V Wölfle, Jörg Fiedler, Lutz Dürselen, Judith Reichert, Dieter Scharnweber, Anne Förster, Bernd Schwenzer, Heiko Reichel, Anita Ignatius, Rolf E Brenner
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86151 (2014)
The aim of the present study was to test the biocompatibility and functionality of orthopaedic bone implants with immobilized oligonucleotides serving as anchor stands for rhBMP-2 and rhVEGF-A conjugated with complementary oligonucleotides in an oste
Externí odkaz:
https://doaj.org/article/78cbdc2a471146c6aa2380e214105f73
Autor:
Markus Huber-Lang, Sinja Rodi, Hubert Schrezenmeier, Rolf E. Brenner, Markus Rojewski, Daniel Fürst, Jörg Fiedler, Annette Palmer, Sonja Braumüller, Elisa Maria Amann
Publikováno v:
Cytotherapy. 20:218-231
Background Effective therapy of Acute Lung Injury (ALI) is still a major scientific and clinical problem. To define novel therapeutic strategies for sequelae of blunt chest trauma (TxT) like ALI/Acute Respiratory Distress Syndrome, we have investigat
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Differential Interactive Effects of Cartilage Traumatization and Blood Exposure In Vitro and In Vivo
Autor:
Jörg Fiedler, Heiko Reichel, Anita Ignatius, Cathrin Hogrefe, Rolf E. Brenner, Jana Riegger, Lutz Dürselen, Helga Joos, Frank Leucht
Publikováno v:
The American Journal of Sports Medicine. 43:2822-2832
Background:Sport injuries of the knee often lead to posttraumatic arthritis. In addition to direct damage of the cartilage, trauma-associated intra-articular bleeding may cause hemarthrosis. Both blood exposure and trauma are known to induce cell dea