Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jörg, Habermann"'
Autor:
Jörg Habermann, Stefania Colarusso, Immacolata Conte, Marcello Di Filippo, Caterina Ercolani, Maria Cecilia Palumbi, Maria del Rosario Rico Ferreira, Simone Zaramella, Angela C. Mackay, Frank Narjes, Ian Stansfield
Publikováno v:
Synlett. 2011:1527-1532
The development of a scalable chiral synthesis for the HCV NS5B inhibitor MK-3281 is being reported. Several alternative routes were explored and are being described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b1088cc8404a4ef3095848cb2384440
https://doi.org/10.1055/s-0030-1260790
https://doi.org/10.1055/s-0030-1260790
Autor:
Paola Baiocco, Angela C. Mackay, Jörg Habermann, Frank Narjes, Raffaele De Francesco, Caterina Ercolani, Giovanni Migliaccio, Stefania Di Marco, Geert Leroux-Roels, Philip Meuleman, Ralph Laufer, Simone Zaramella, Stefania Colarusso, Immacolata Conte, Fabrizio Fiore, Michael Rowley, Sergio Altamura, Maria del Rosario Rico Ferreira, Benedetta Crescenzi, Uwe Koch, Ian Stansfield, Claudio Giuliano, Maria-Cecilia Palumbi, Marco Ferrara
Publikováno v:
Journal of Medicinal Chemistry. 54:289-301
Infections caused by hepatitis C virus (HCV) are a significant world health problem for which novel therapies are in urgent demand. The polymerase of HCV is responsible for the replication of viral genome and has been a prime target for drug discover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82030f2a14c890d541baefe4cd5f15d9
https://doi.org/10.1021/jm1013105
https://doi.org/10.1021/jm1013105
Autor:
Jörg Habermann
Publikováno v:
Current Organic Chemistry. 14:1139-1152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b74f5f66b7fcfe1e8899543698becad9
https://doi.org/10.2174/138527210791317085
https://doi.org/10.2174/138527210791317085
Autor:
Fabrizio Fiore, Maria del Rosario Rico Ferreira, Barbara Attenni, Savina Malancona, Simona Ponzi, Jesus Maria Ontoria Ontoria, Jose Ignacio Martin Hernando, Stefania Di Marco, Michael Rowley, Frank Narjes, Stefania Colarusso, Sue Ellen Vignetti, Fabio Bonelli, Uwe Koch, Jörg Habermann, Nadia Gennari
Publikováno v:
ChemMedChem. 4:1695-1713
Infections caused by the hepatitis C virus (HCV) are a significant world health problem for which novel therapies are in urgent demand. The NS5B polymerase of HCV is responsible for the replication of viral RNA and has been a prime target in the sear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f153469e7aabaa8dda229fceffb28510
https://doi.org/10.1002/cmdc.200900184
https://doi.org/10.1002/cmdc.200900184
Publikováno v:
Angewandte Chemie International Edition. 41:4249-4252
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e35bb5d1764cb5ff067fc0504b4612
https://doi.org/10.1002/1521-3773(20021115)41:22<4249::aid-anie4249>3.0.co
https://doi.org/10.1002/1521-3773(20021115)41:22<4249::aid-anie4249>3.0.co
Publikováno v:
Angewandte Chemie. 114:4423-4426
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f1f151a6647425877b0a88c6c283af9
https://doi.org/10.1002/1521-3757(20021115)114:22<4423::aid-ange4423>3.0.co
https://doi.org/10.1002/1521-3757(20021115)114:22<4423::aid-ange4423>3.0.co
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1253-1256
A ten-step synthesis of (±)-epibatidine 1 is described, using an organised array of polymer supported reagents and sequestering agents in a successive manner. No chromatographic purification steps are required to afford the product in >90% purity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df68b06925b075b0fd514cd4c76f34f4
https://doi.org/10.1039/a901802f
https://doi.org/10.1039/a901802f
Autor:
Horst Kunz, Jörg Habermann
Publikováno v:
Tetrahedron Letters. 39:4797-4800
The lipo-glycopeptide 6 containing the homophilic recognition motif of mouse epithelial cadherin 1 was synthesised via a fragment condensation on a solid phase linked peptide using an allylic anchor and a pentafluorophenol-based coupling reagent.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b70f0a5b3484614d7edc50cd9654eeac
https://doi.org/10.1016/s0040-4039(98)00923-x
https://doi.org/10.1016/s0040-4039(98)00923-x
Autor:
Jörg Habermann, Horst Kunz
Publikováno v:
Journal f�r Praktische Chemie/Chemiker-Zeitung. 340:233-239
Pentafluorophenyluronium salts and related coupling reagents for the solid-phase synthesis of peptides and glycopeptides have been developed and employed in the synthesis of a glycopeptide sequence from the cell adhesion molecule E-CAD 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2deed883f318461cee4e6892ba63e8cf
https://doi.org/10.1002/prac.19983400306
https://doi.org/10.1002/prac.19983400306
Autor:
Jörg Habermann, Horst Kunz
Publikováno v:
Tetrahedron Letters. 39:265-268
The β-turn forming glycopeptide 6 from the homophilic recognition domain of mouse epithelial cadherin 1 carrying a T N -antigen side chain was synthesised on solid phase using an allylic anchor and the new coupling reagent N , N - N ′, N ′-bis(t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9a143e526d48e73d8573428e5101796
https://doi.org/10.1016/s0040-4039(97)10569-x
https://doi.org/10.1016/s0040-4039(97)10569-x