Zobrazeno 1 - 10
of 17
pro vyhledávání: '"József Murányi"'
Autor:
Gábor Bögel, József Murányi, Bálint Szokol, Zoltán Kukor, István Móra, Tamás Kardon, László Őrfi, András Hrabák
Publikováno v:
Heliyon, Vol 8, Iss 1, Pp e08670- (2022)
JAK/STAT pathway plays a well-known role in macrophage polarization, but other signaling routes may also be involved. The aim of this study was to identify new signaling pathways and repolarize macrophages by selected protein kinase inhibitors. HL-60
Externí odkaz:
https://doaj.org/article/8d69a1286fd64981bb1ef2a7c567d0de
Autor:
Attila Varga, Minh Tu Nguyen, Kinga Pénzes, Bence Bátai, Pál Gyulavári, Bianka Gurbi, József Murányi, Péter Csermely, Miklós Csala, Tibor Vántus, Csaba Sőti
Publikováno v:
Cells, Vol 12, Iss 2, p 212 (2023)
Prostate cancer metastasis is a significant cause of mortality in men. PKD3 facilitates tumor growth and metastasis, however, its regulation is largely unclear. The Hsp90 chaperone stabilizes an array of signaling client proteins, thus is an enabler
Externí odkaz:
https://doaj.org/article/a25c4d7aca6d4c5f82f3e3ec898a3af3
Autor:
Mo’ath Yousef, Ildikó Szabó, József Murányi, Françoise Illien, Dóra Soltész, Csaba Bató, Gabriella Tóth, Gyula Batta, Péter Nagy, Sandrine Sagan, Zoltán Bánóczi
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 141 (2022)
Cell-penetrating peptides represent an emerging class of carriers capable of effective cellular delivery. This work demonstrates the preparation and investigation of efficient CPPs. We have already shown that the presence of 4-((4-(dimethylamino)phen
Externí odkaz:
https://doaj.org/article/4d7fc7b8b4d047cfb3506feb7a9f7d34
Autor:
Tamás Czuczi, József Murányi, Péter Bárány, István Móra, Adina Borbély, Miklós Csala, Antal Csámpai
Publikováno v:
Pharmaceuticals, Vol 15, Iss 4, p 468 (2022)
Imipridones, including ONC201, ONC206 and ONC212 (which are emblematic members of this class of compounds developed by Oncoceutics) constitute a novel class of anticancer agents, with promising results in clinical trials. With the aim of increasing t
Externí odkaz:
https://doaj.org/article/754deb64b98c4fbcb5d62e61c85c104d
Autor:
András, Hrabák, Gábor, Bögel, József, Murányi, Viola, Tamási, Krisztina, Németh, Bálint, Szokol, Zoltán, Kukor, Tamás, Kardon, László, Őrfi
Publikováno v:
Molecular Immunology. 153:10-24
The JAK/STAT (Janus Kinase/Signal Transducer and Activator of Transcription) pathway plays a pivotal role in macrophage polarization, but other signaling routes may also be involved. The aim of this study was to reveal the relationship of activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e684199e2eb443102d23f33cd0a9cb5
https://doi.org/10.1016/j.molimm.2022.11.002
https://doi.org/10.1016/j.molimm.2022.11.002
Autor:
József Murányi, Cintia Duró, Bianka Gurbi, István Móra, Attila Varga, Krisztina Németh, József Simon, Miklós Csala, Antal Csámpai
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 3456
Volume 24
Issue 4
Pages: 3456
In a search for novel therapeutic options for head and neck squamous cell carcinomas (HNSCCs) generally treated with limited therapeutic success, we synthesized a series of novel erlotinib–chalcone molecular hybrids with 1,2,3-triazole and alkyne l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdbf6b8289ac544e81c863c1a3542ae
Autor:
Gábor Bögel, József Murányi, Bálint Szokol, Zoltán Kukor, István Móra, Tamás Kardon, László Őrfi, András Hrabák
Publikováno v:
Heliyon
Heliyon, Vol 8, Iss 1, Pp e08670-(2022)
Heliyon, Vol 8, Iss 1, Pp e08670-(2022)
JAK/STAT pathway plays a well-known role in macrophage polarization, but other signaling routes may also be involved. The aim of this study was to identify new signaling pathways and repolarize macrophages by selected protein kinase inhibitors. HL-60
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ea0cbbf215c2185a34881b010607024
https://pubmed.ncbi.nlm.nih.gov/35028455
https://pubmed.ncbi.nlm.nih.gov/35028455
Autor:
Pál Gyulavári, József Murányi, István Peták, Csilla E. Németh, Lilla Pethő, Attila Varga, István Vályi-Nagy, Kinga Pénzes, Miklós Csala, Antal Csámpai, Gabor Halmos
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5590 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 22
International Journal of Molecular Sciences
Volume 20
Issue 22
Several promising anti-cancer drug&ndash
GnRH (gonadotropin-releasing hormone) conjugates have been developed in the last two decades, although none of them have been approved for clinical use yet. Crizotinib is an effective multi-target kinase
GnRH (gonadotropin-releasing hormone) conjugates have been developed in the last two decades, although none of them have been approved for clinical use yet. Crizotinib is an effective multi-target kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71afbaeb9f169438fd807e01dfaa6f4b
https://www.mdpi.com/1422-0067/20/22/5590
https://www.mdpi.com/1422-0067/20/22/5590
Autor:
Bianka Gurbi, Diána Brauswetter, Gabor Halmos, József Murányi, Lilla Pethő, Kinga Pénzes, Gabriella Csík, Gábor Mező
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5027 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 20
International Journal of Molecular Sciences
Volume 20
Issue 20
Head and neck squamous cell carcinomas (HNSCC) have a high mortality rate, although several potential therapeutic targets have already been identified. Gonadotropin-releasing hormone receptor (GnRH-R) expression is less studied in head and neck cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da99bfb39339c2ef8ea86abf0368f51d
https://www.mdpi.com/1422-0067/20/20/5027
https://www.mdpi.com/1422-0067/20/20/5027
Autor:
Györgyi Bökönyi, Attila Varga, Krisztina Ludányi, György Kéri, Tibor Vántus, Pál Gyulavári, Domonkos Pap, József Murányi, Henriette Tanai, Gábor Mező
Publikováno v:
Journal of Peptide Science. 22:552-560
Targeted tumour therapy is the focus of recent cancer research. Gonadotropin-releasing hormone (GnRH) analogues are able to deliver anticancer agents selectively into tumour cells, which highly express GnRH receptors. However, the effectiveness of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02c3cc3cd3279c98b8c542d8612a7cb3
https://doi.org/10.1002/psc.2904
https://doi.org/10.1002/psc.2904