Zobrazeno 1 - 10
of 39
pro vyhledávání: '"József Jászai"'
Publikováno v:
Reproductive Medicine and Biology, Vol 22, Iss 1, Pp n/a-n/a (2023)
Abstract The contribution of Prominin‐1 (aka CD133) to male fertility has recently been (re)investigated, with contradictory results. Early findings, essential for deciphering its role, have unfortunately been neglected. Here, the authors present w
Externí odkaz:
https://doaj.org/article/b36d2e81b0c5431cb47faa81d9b1a9ad
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract Ischemic retinal dystrophies are leading causes of acquired vision loss. Although the dysregulated expression of the hypoxia-responsive VEGF-A is a major driver of ischemic retinopathies, implication of additional VEGF-family members in thei
Externí odkaz:
https://doaj.org/article/6774ec12cbe6423b8646f647eb2f6254
Publikováno v:
Biomedicines, Vol 10, Iss 2, p 201 (2022)
Anti-Vascular Endothelial Growth Factor (VEGF) agents are the first-line treatment for retinal neovascular diseases, which represent the most prevalent causes of acquired vision loss world-wide. VEGF-Trap (Aflibercept, AFL), a recombinant decoy recep
Externí odkaz:
https://doaj.org/article/92e9ef06aada4c9ea739de7b117e602a
Autor:
József Jászai, Mirko H.H. Schmidt
Publikováno v:
Cells, Vol 8, Iss 9, p 1102 (2019)
Excessive abnormal angiogenesis plays a pivotal role in tumor progression and is a hallmark of solid tumors. This process is driven by an imbalance between pro- and anti-angiogenic factors dominated by the tissue hypoxia-triggered overproduction of v
Externí odkaz:
https://doaj.org/article/b014a9c0880e4f1fa4ad6d7f128470b6
Autor:
József Jászai, Sylvi Graupner, Elly M Tanaka, Richard H W Funk, Wieland B Huttner, Michael Brand, Denis Corbeil
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63457 (2013)
In mammals, embryonic neural progenitors as well as adult neural stem cells can be prospectively isolated based on the cell surface expression of prominin-1 (CD133), a plasma membrane glycoprotein. In contrast, characterization of neural progenitors
Externí odkaz:
https://doaj.org/article/425077e30ec4481f833850975d300b22
Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species.
Autor:
József Jászai, Christine A Fargeas, Sylvi Graupner, Elly M Tanaka, Michael Brand, Wieland B Huttner, Denis Corbeil
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17590 (2011)
Besides being a marker of various somatic stem cells in mammals, prominin-1 (CD133) plays a role in maintaining the photoreceptor integrity since mutations in the PROM1 gene are linked with retinal degeneration. In spite of that, little information i
Externí odkaz:
https://doaj.org/article/e891263ee54b405b85ddc2b9068d7832
Autor:
Henning, Morawietz, Annika, Frenzel, Alice, Mieting, Winfried, Goettsch, Monika, Valtink, Cora, Roehlecke, József, Jászai, Richard H W, Funk, Klio A, Becker, Katrin, Engelmann
Publikováno v:
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis TherapyREFERENCES. 26
Low-density lipoprotein (LDL) apheresis is effective and safe for patients with diabetes, proteinuria, and dyslipidemia. Diabetes mellitus is accompanied by ocular microvascular complications like retinal neovascularization or diabetic macular edema.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2f7a6f2c2873663b1114690342861dd
https://pubmed.ncbi.nlm.nih.gov/36468302
https://pubmed.ncbi.nlm.nih.gov/36468302
Publikováno v:
Biomedicines. 10(2)
Anti-Vascular Endothelial Growth Factor (VEGF) agents are the first-line treatment for retinal neovascular diseases, which represent the most prevalent causes of acquired vision loss world-wide. VEGF-Trap (Aflibercept, AFL), a recombinant decoy recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a97ca43c83ca965f73f4e1d4f6ebd4
https://pubmed.ncbi.nlm.nih.gov/35203414
https://pubmed.ncbi.nlm.nih.gov/35203414
Autor:
Vanessa Englmaier, Matina Economopoulou, David A. Juárez López, Martin Schaarschmidt, Henning Morawietz, Anica Kurzbach, József Jászai, Marie Merdausl, Richard Funk, Marius Ader, Kwan H. Au Yeung, Jesus Eduardo Rojo Arias
Publikováno v:
Journal of Neurochemistry. 153:390-412
Retinal hypoxia triggers abnormal vessel growth and microvascular hyper-permeability in ischemic retinopathies. Whereas vascular endothelial growth factor A (VEGF-A) inhibitors significantly hinder disease progression, their benefits to retinal neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b975363f83c67301fc8602a9ab9c57
https://doi.org/10.1111/jnc.14875
https://doi.org/10.1111/jnc.14875
Autor:
Frederik Raiskup, Matina Economopoulou, Andreas Androutsellis-Theotokis, Triantafyllos Chavakis, Monika Ehrhart-Bornstein, Sarama Saha, Lutz E Pillunat, Anna Dubrovska, Leoni A. Kunz-Schughart, József Jászai, Doreen Ebermann, Richard Funk, Mike O. Karl, Jimmy Masjkur, I. Kurth
Publikováno v:
International Journal of Radiation Biology. 90:700-709
Purpose: In this work we examined the presence of the neural stem cell biomarker Hairy and Enhancer of Split 3 (Hes3) in the anterior eye segment and in the aberrant growth condition of the conjunctiva pterygium. Further, we studied the response of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e673c17f743a8d544f797cdb53833aa
https://doi.org/10.3109/09553002.2014.892228
https://doi.org/10.3109/09553002.2014.892228