Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Józef Szczech"'
Autor:
Józef Szczech, Wojciech Kozubski, Anna Kowalska, Jolanta Florczak, Renata Modestowicz, Grzegorz Rossa, Danuta Pruchnik-Wolinska, Mieczysław Wender
Publikováno v:
Acta Biochimica Polonica. 51:245-252
A small number (1-5%) of Alzheimer's disease (AD) cases associated with the early-onset form of the disease (EOAD) appears to be transmitted as a pure genetic, autosomal dominant trait. To date, three genes responsible for familial EOAD have been ide
Publikováno v:
Folia neuropathologica. 43(2)
The elucidation of various aspects of the pathomechanism of experimental cardiac arrest may contribute valuable information for the treatment of cardiac arrests in humans. The model of clinical death in rats introduced by Korpatchev et al. was used.
Autor:
Anna, Kowalska, Danuta, Pruchnik-Wolińska, Jolanta, Florczak, Józef, Szczech, Wojciech, Kozubski, Grzegorz, Rossa, Mieczysław, Wender
Publikováno v:
Folia neuropathologica. 42(1)
The beta-amyloid precursor protein (APP) gene (on chromosome 21), Presenilin 1 (PS1) gene (on chromosome 14) and Presenilin 2 (PS2) gene (on chromosome 1) are responsible for autosomal dominant early-onset Alzheimer's disease (EOAD). Missense mutatio
Autor:
Anna, Kowalska, Danuta, Pruchnik-Wolińska, Jolanta, Florczak, Józef, Szczech, Wojciech, Kozubski, Grzegorz, Rossa, Mieczysław, Wender
Publikováno v:
Folia neuropathologica. 42(1)
Mutations in Presenilin 1 (PS1) and Presenilin 2 (PS2) genes account for up to 50% of familial early-onset Alzheimer's disease (EOAD). In order to assess the genetic contribution of the PS genes in a series of Polish patients, we performed a mutation
Autor:
Anna, Kowalska, Mieczyslaw, Wender, Jolanta, Florczak, Danuta, Pruchnik-Wolinska, Renata, Modestowicz, Józef, Szczech, Grzegorz, Rossa, Wojciech, Kozubski
Publikováno v:
Journal of applied genetics. 44(2)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by memory loss and personality changes. Pathological hallmarks of AD are: deposition of amyloid plaques and neurofibrillary tangles in the brain, accompanied by neuron
Publikováno v:
Acta Histochemica. 71:175-182
Summary Karyometric and cytophotometric investigations were conducted on nuclei of nerve cells of the Gyrus cinguli and on oligodendroglial nuclei of the corpus callosum following a 12-fold intraperitoneal injection of Vincristine into Wistar rats. T
Autor:
Antoni Godlewski, Józef Szczech
Publikováno v:
Acta Histochemica. 78:147-164
Summary BCNU is a nitrosourea derivative applied in anti-neoplastic therapy. As a result of conversion under in vivo -conditions, products of alkylating properties are formed which derrange DNA metabolism, and products of carbamylating activity which
Autor:
Józef Szczech
Publikováno v:
Acta Histochemica. 81:99-107
Summary Studies on the effect of BCNU (Carmustine), administered in 4 intraperitoneal injections of 7.5 mg each, on cell nuclei of blood vessel endothelia were performed on the parietal cortex and the thalamus of 20 adult rats of Wistar strain. Karyo