Effect of sevoflurane on the inflammatory response during cardiopulmonary bypass in cardiac surgery: the study protocol for a randomized controlled trial

Autor: Thiago Augusto Azevedo Maranhão Cardoso, Gudrun Kunst, Caetano Nigro Neto, José de Ribamar Costa Júnior, Carlos Gustavo Santos Silva, Gisele Medeiros Bastos, Jéssica Bassani Borges, Mario Hiroyuki Hirata

Publikováno v: Trials, Vol 22, Iss 1, Pp 1-10 (2021)

Abstract Background Recent experimental evidence shows that sevoflurane can reduce the inflammatory response during cardiac surgery with cardiopulmonary bypass. However, this observation so far has not been assessed in an adequately powered randomize

Externí odkaz: https://doaj.org/article/400b319d2f2c48a4ae6527b3adbb30e8

Identification of pathogenic variants in the Brazilian cohort with Familial hypercholesterolemia using exon-targeted gene sequencing

Autor: Jéssica Bassani Borges, Victor Fernandes Oliveira, Carolina Dagli-Hernandez, Glaucio Monteiro Ferreira, Thais Kristini Almendros Afonso Barbosa, Elisangela da Silva Rodrigues Marçal, Bruna Los, Vanessa Barbosa Malaquias, Raul Hernandes Bortolin, Renata Caroline Costa Freitas, Augusto Akira Mori, Gisele Medeiros Bastos, Rodrigo Marques Gonçalves, Daniel Branco Araújo, Henry Zatz, Adriana Bertolami, André Arpad Faludi, Marcelo Chiara Bertolami, Amanda Guerra de Moraes Rego Souza, João Ítalo Dias França, Helena Strelow Thurow, Thiago Dominguez Crespo Hirata, Helder Takashi Imoto Nakaya, Cinthia Elim Jannes, Alexandre da Costa Pereira, Vivian Nogueira Silbiger, André Ducati Luchessi, Jéssica Nayara Góes Araújo, Marcelo Arruda Nakazone, Tayanne Silva Carmo, Dorotéia Rossi Silva Souza, Patricia Moriel, Jaqueline Yu Ting Wang, Michel Satya Naslavsky, Renata Gorjão, Tania Cristina Pithon-Curi, Rui Curi, Cristina Moreno Fajardo, Hui-Tzu Lin Wang, Adriana Regina Garófalo, Alvaro Cerda, Marcelo Ferraz Sampaio, Rosario Dominguez Crespo Hirata, Mario Hiroyuki Hirata

Publikováno v: Gene. 875:147501

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da17601c89281cd8f6bae0c732c17a98
https://doi.org/10.1016/j.gene.2023.147501

Genetic Variant

Autor: Carolina, Dagli-Hernandez, Jéssica Bassani, Borges, Elisangela da Silva Rodrigues, Marçal, Renata Caroline Costa, de Freitas, Augusto Akira, Mori, Rodrigo Marques, Gonçalves, Andre Arpad, Faludi, Victor Fernandes, de Oliveira, Glaucio Monteiro, Ferreira, Gisele Medeiros, Bastos, Yitian, Zhou, Volker M, Lauschke, Alvaro, Cerda, Mario Hiroyuki, Hirata, Rosario Dominguez Crespo, Hirata

Publikováno v: Pharmaceutics. 14(5)

Statins are the first-line treatment for familial hypercholesterolemia (FH), but response is highly variable due to genetic and nongenetic factors. Here, we explored the association between response and genetic variability in 114 Brazilian adult FH p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f424fc3c65fe7acbb7109dbc622c7389
https://pubmed.ncbi.nlm.nih.gov/35631530

LDLR missense variants disturb structural conformation and LDLR activity in T-lymphocytes of Familial hypercholesterolemia patients

Autor: Thais Kristini Almendros, Barbosa, Rosario Dominguez Crespo, Hirata, Glaucio Monteiro, Ferreira, Jéssica Bassani, Borges, Victor Fernandes de, Oliveira, Renata, Gorjão, Elisangela Rodrigues da Silva, Marçal, Rodrigo Marques, Gonçalves, André Arpad, Faludi, Renata Caroline Costa de, Freitas, Carolina, Dagli-Hernandez, Raul Hernandes, Bortolin, Gisele Medeiros, Bastos, Tania Cristina, Pithon-Curi, Helena Bonciani, Nader, Mario Hiroyuki, Hirata

Publikováno v: Gene. 853:147084

Familial hypercholesterolemia (FH) is caused by deleterious mutations in the LDLR that increase markedly low-density lipoprotein (LDL) cholesterol and cause premature atherosclerotic cardiovascular disease. Functional effects of pathogenic LDLR varia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e2da35a8a76cce65f9ee0af6fa59c5
https://doi.org/10.1016/j.gene.2022.147084

Increased levels of plasma IL-1b and BDNF can predict resistant depression patients

Autor: Gisele Medeiros Bastos, Jéssica Bassani Borges, Joao Italo Dias França, Thiago Dominguez Crespo Hirata, Helena Strelow Thurow, Amanda G. M. R. Sousa, Luciana Uint, Mario Hiroyuki Hirata

Publikováno v: Revista da Associação Médica Brasileira, Vol 65, Iss 3, Pp 361-369 (2019)
Revista da Associação Médica Brasileira v.65 n.3 2019
Revista da Associação Médica Brasileira
Associação Médica Brasileira (AMB)
instacron:AMB
Revista da Associação Médica Brasileira, Volume: 65, Issue: 3, Pages: 361-369, Published: 11 APR 2019

SUMMARY BACKGROUND: There is no strong evidence on the link between inflammatory profile and pattern of drug treatment response in depressive patients that could result in Coronary Artery Disease occurrence. OBJECTIVE: This study aimed to compare the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a361fd38acc6ce076676e63ffefce0
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302019000300361&lng=en&tlng=en