Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jéssica B de Jesus"'
Autor:
Douglas O Escrivani, Rebecca L Charlton, Marjolly B Caruso, Gabriela A Burle-Caldas, Maria Paula G Borsodi, Russolina B Zingali, Natalia Arruda-Costa, Marcos V Palmeira-Mello, Jéssica B de Jesus, Alessandra M T Souza, Bárbara Abrahim-Vieira, Stefanie Freitag-Pohl, Ehmke Pohl, Paul W Denny, Bartira Rossi-Bergmann, Patrick G Steel
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009951 (2021)
With current drug treatments failing due to toxicity, low efficacy and resistance; leishmaniasis is a major global health challenge that desperately needs new validated drug targets. Inspired by activity of the natural chalcone 2',6'-dihydroxy-4'-met
Externí odkaz:
https://doaj.org/article/97dcebeea4914662b9ca60f477d72118
Autor:
JÉSSICA B. DE JESUS, RAISSA A. DA CONCEIÇÃO, THAYNÁ R. MACHADO, MARIA L.C. BARBOSA, THAISA F.S. DOMINGOS, LUCIO M. CABRAL, CARLOS R. RODRIGUES, BÁRBARA ABRAHIM-VIEIRA, ALESSANDRA M.T. DE SOUZA
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 94, Iss suppl 3 (2022)
Abstract Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are the latest class of drugs approved to treat type 2 DM (T2DM). Although adverse effects are often caused by a metabolite rather than the drug itself, only the safety assessment of disprop
Externí odkaz:
https://doaj.org/article/d7315ccc43f24e79baf2d5d9959383c4
Autor:
Ana Claudia F. Amaral, Andreza R. Garcia, Ana Carolina Rennó Sodero, Claudiu T. Supuran, Alessandra Mendonça Teles de Souza, Anderson S. Pinheiro, Igor A. Rodrigues, Alane Beatriz Vermelho, Jéssica B. de Jesus, Danielle M.P. Oliveira
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1100-1109 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1100-1109 (2019)
Inhibition of Leishmania arginase leads to a decrease in parasite growth and infectivity and thus represents an attractive therapeutic strategy. We evaluated the inhibitory potential of selected naturally occurring phenolic substances on Leishmania i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba5ef66fe17f309da7e139727696245
https://doi.org/10.1080/14756366.2019.1616182
https://doi.org/10.1080/14756366.2019.1616182
Autor:
Maria Cecília B. V. de Souza, Taísa Fortes Santos, Vinícius R. Campos, Vitor F. Ferreira, Paulo Murillo Neufeld, Carlos Rangel Rodrigues, Anna C. Cunha, Alessandro K. Jordão, Jéssica B. de Jesus, Paula Alvarez Abreu, Helena Carla Castro
Publikováno v:
Medicinal Chemistry Research. 26:680-689
Candidiasis is a serious public health problem that currently affects not only immunodeficient patients with predisposing conditions, but also immunocompetent individuals. Thus, the search for new antifungal agents is required also due to the emergen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d36c744633abd2704a7402eac17279a
https://doi.org/10.1007/s00044-017-1789-x
https://doi.org/10.1007/s00044-017-1789-x
Autor:
Jéssica B. de Jesus, Maria Isabel C Rodrigues, Ana Carolina G O Dos Santos, Salvatore Giovanni De Simone, Herbert Leonel de Matos Guedes, Ana Carolina Rennó Sodero, Carlos Rangel Rodrigues, Alessandra Mendonça Teles de Souza, Juliana da Fonseca Rezende e Mello
Publikováno v:
Parasitology. 144:536-545
SUMMARYLeishmaniasis are diseases caused by parasites of the genus Leishmania and transmitted to humans by the bite of infected insects of the subfamily Phlebotominae. Current drug therapy shows high toxicity and severe adverse effects. Recently, two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c956769e9ee87c4efc2816b4158c4f
https://doi.org/10.1017/s0031182016002237
https://doi.org/10.1017/s0031182016002237
Autor:
Jéssica B. de Jesus, Bárbara Abrahim-Vieira, Alessandra Mendonça Teles de Souza, Carlos Rangel Rodrigues, Thaisa Francielle Souza Domingos, Marcos Vinícius Palmeira de Mello, Ana Carolina Corrêa de Sousa
Publikováno v:
European journal of medicinal chemistry. 150
Leishmaniasis is a group of infectious neglected tropical diseases caused by more than 20 pathogenic species of Leishmania sp. Due to the limitations of the current treatments available, chalcone moiety has been drawn with a lot of attention due to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659d261f30959f38067dc0ef8f0b0518
https://pubmed.ncbi.nlm.nih.gov/29602038
https://pubmed.ncbi.nlm.nih.gov/29602038