Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Jérome Solassol"'
Autor:
Eric Frouin, Bernard Guillot, Marion Larrieux, Ariane Tempier, Nathalie Boulle, Vincent Foulongne, Céline Girard, Valérie Costes, Jérome Solassol
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110478 (2014)
The inhibitors of mutant BRAF that are used to treat metastatic melanoma induce squamoproliferative lesions. We conducted a prospective histopathological and molecular study on 27 skin lesions from 12 patients treated with vemurafenib. Mutation hot s
Externí odkaz:
https://doaj.org/article/9918ff517b0245bb98b029d761f91aec
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 12, Pp 9737-9752 (2023)
Next-generation sequencing (NGS) has taken on major importance in clinical oncology practice. With the advent of targeted therapies capable of effectively targeting specific genomic alterations in cancer patients, the development of bioinformatics pr
Externí odkaz:
https://doaj.org/article/6f620beb82b34454a4853126c4c23f45
Autor:
Iulian O. Ban, Alice Chabert, Thomas Guignard, Jacques Puechberty, Simon Cabello-Aguilar, Pascal Pujol, Julie A. Vendrell, Jérôme Solassol
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionAccurate identification and characterization of Large Genomic Rearrangements (LGR), especially duplications, are crucial for precise diagnosis and risk assessment. In this report, we characterized an intragenic duplication breakpoint of P
Externí odkaz:
https://doaj.org/article/476bc9d5b9164fcab4492b6136f55df5
Autor:
Simon Cabello-Aguilar, Julie A. Vendrell, Charles Van Goethem, Mehdi Brousse, Catherine Gozé, Laurent Frantz, Jérôme Solassol
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 174-183 (2022)
Copy-number variations (CNVs) are an essential component of genetic variation distributed across large parts of the human genome. CNV detection from next-generation sequencing data and artificial intelligence algorithms have progressed in recent year
Externí odkaz:
https://doaj.org/article/d38e06b160a4414382a8f7062ccdc4db
Autor:
Quentin Dominique Thomas, Julien Colard-Thomas, Delphine Delansay, Fanny Leenhardt, Jerome Solassol, Julie A. Vendrell, Xavier Quantin
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The detection of circulating tumor DNA (ctDNA) by liquid biopsy is taking an increasing role in thoracic oncology management due to its predictive and prognostic value. For non-small cell lung cancer, it allows the detection of molecular mutations th
Externí odkaz:
https://doaj.org/article/c4256822ac1d4b32936effa6be87ef77
Autor:
Aurélie Bellanger, Diep T. Le, Julie Vendrell, Anne Wierinckx, Lőrinc S. Pongor, Jérôme Solassol, Joël Lachuer, Philippe Clezardin, Balázs Győrffy, Pascale A. Cohen
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Oncogene alternative splicing events can create distinct functional transcripts that offer new candidate prognostic biomarkers for breast cancer. ZNF217 is a well-established oncogene but its exon 4-skipping isoform (ZNF217-ΔE4) has never been inves
Externí odkaz:
https://doaj.org/article/447ddc6507a346b49865519fc7d3eb12
Autor:
Jérôme Lacombe, Muriel Brengues, Alain Mangé, Céline Bourgier, Sophie Gourgou, André Pèlegrin, Mahmut Ozsahin, Jérôme Solassol, David Azria
Publikováno v:
Radiation Oncology, Vol 14, Iss 1, Pp 1-11 (2019)
Abstract Background Biomarkers for predicting late normal tissue toxicity to radiotherapy are necessary to personalize treatments and to optimize clinical benefit. Many radiogenomic studies have been published on this topic. Conversely, proteomics ap
Externí odkaz:
https://doaj.org/article/6467dd72a28346129ffe48e7196fef29
Autor:
Oumar Ouchar Mahamat, Manon Lounnas, Mallorie Hide, Yann Dumont, Abelsalam Tidjani, Kadidja Kamougam, Madina Abderrahmane, Julio Benavides, Jérôme Solassol, Anne-Laure Bañuls, Hélène jean-Pierre, Christian Carrière, Sylvain Godreuil
Publikováno v:
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background Extended-spectrum ß-lactamase-producing Enterobacteriaceae (ESBL-PE) represent a major problem in the management of nosocomial infections. However, ESBL-PE are not systematically monitored in African countries. The aim of this st
Externí odkaz:
https://doaj.org/article/f04205e671cc4ad2b7a0602512076cb1
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Histological transformation of advanced non-small cell lung cancer (NSCLC) to small cell lung cancer (SCLC) is one of the mechanisms of resistance to third-generation tyrosine kinase inhibitors (TKIs), such as osimertinib. This acquired T
Externí odkaz:
https://doaj.org/article/8cc493f73bd94b3497491fbd3dc9ae09
Autor:
Jean-André Lapart, Marco Gottardo, Elisabeth Cortier, Jean-Luc Duteyrat, Céline Augière, Alain Mangé, Julie Jerber, Jérôme Solassol, Jay Gopalakrishnan, Joëlle Thomas, Bénédicte Durand
Publikováno v:
eLife, Vol 8 (2019)
Cilia and flagella are conserved eukaryotic organelles essential for cellular signaling and motility. Cilia dysfunctions cause life-threatening ciliopathies, many of which are due to defects in the transition zone (TZ), a complex structure of the cil
Externí odkaz:
https://doaj.org/article/5b7e7224f33e4fff800d99b41806cf7a