Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jérome Mégret"'
Autor:
Nicolas Goudin, Pascal Chappert, Jérome Mégret, David-Alexandre Gross, Benedita Rocha, Orly Azogui
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0171373 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0157822.].
Externí odkaz:
https://doaj.org/article/3c551e9afe934c46bde184fbcd224cbe
Autor:
Nicolas Goudin, Pascal Chappert, Jérome Mégret, David-Alexandre Gross, Benedita Rocha, Orly Azogui
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157822 (2016)
Natural regulatory T (Treg) cells interfere with multiple functions, which are crucial for the development of strong anti-tumour responses. In a model of 4T1 mammary carcinoma, depletion of CD25+Tregs results in tumour regression in Balb/c mice, but
Externí odkaz:
https://doaj.org/article/26b1dd3a845a40798e637919e12dbbe6
Autor:
Pascal Chappert, François Huetz, Marie-Alix Espinasse, Fabrice Chatonnet, Louise Pannetier, Lucie Da Silva, Clara Goetz, Jérome Mégret, Aurélien Sokal, Etienne Crickx, Ivan Nemazanyy, Vincent Jung, Chiara Guerrera, Sébastien Storck, Matthieu Mahévas, Antonio Cosma, Patrick Revy, Thierry Fest, Claude-Agnès Reynaud, Jean-Claude Weill
Publikováno v:
Immunity
Immunity, 2022, 55 (10), pp.1872-1890. ⟨10.1016/j.immuni.2022.08.019⟩
Immunity, 2022, 55 (10), pp.1872-1890. ⟨10.1016/j.immuni.2022.08.019⟩
International audience; Memory B cells (MBCs) can persist for a lifetime, but the mechanisms that allow their long-term survival remain poorly understood. Here, we isolated and analyzed human splenic smallpox/vaccinia protein B5-specific MBCs in indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498ee5d60841efc1ac61fc7ebb6363d3
https://doi.org/10.1016/j.immuni.2022.08.019
https://doi.org/10.1016/j.immuni.2022.08.019
Autor:
Rima Elhage, Mairead Kelly, Nicolas Goudin, Jérôme Megret, Agnès Legrand, Ivan Nemazanyy, Cécilia Patitucci, Véronique Quellec, Timothy Wai, Ahmed Hamaï, Sophie Ezine
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Several studies demonstrated that mitochondrial dynamics and metabolic pathways control T cell fate in the periphery. However, little is known about their implication in thymocyte development. Our results showed that thymic progenitors (CD3-CD4-CD8-
Externí odkaz:
https://doaj.org/article/8179045982c54527bc94f4e88502b947
Autor:
Anais Julien, Anuya Kanagalingam, Ester Martínez-Sarrà, Jérome Megret, Marine Luka, Mickaël Ménager, Frédéric Relaix, Céline Colnot
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Bone regeneration involves activation of tissue resident stem cells. Here the authors show that mesenchymal progenitors from skeletal muscle mediate the fibrotic response to bone injury and also contribute to bone repair; processes that are impaired
Externí odkaz:
https://doaj.org/article/dd20a96647074b60be4f052131764d93
Autor:
Hélène Letscher, Viviane A. Agbogan, Sarantis Korniotis, Pauline Gastineau, Emmanuel Tejerina, Christophe Gras, Jérôme Mégret, Alison Moe, William R. Drobyski, Flora Zavala
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Early innate education of hematopoietic progenitors within the bone marrow (BM) stably primes them for either trained immunity or instead immunoregulatory functions. We herein demonstrate that in vivo or in vitro activation within the BM via
Externí odkaz:
https://doaj.org/article/c4fd5c13ee9141009cc44b6049bbacf9
Autor:
Sarantis Korniotis, Christophe Gras, Hélène Letscher, Ruddy Montandon, Jérôme Mégret, Stefanie Siegert, Sophie Ezine, Padraic G. Fallon, Sanjiv A. Luther, Simon Fillatreau, Flora Zavala
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Evidence of how functional Bregs develop in vivo has been lacking. Here the authors show that proB cells exposed in vivoto CpG differentiate into distinct Breg subsets that inhibit autoimmunity by arresting T cells in the lymph nodes via CCL19 and by
Externí odkaz:
https://doaj.org/article/b7d9504d2aed4006b464e2e920a9a15c