Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Jérôme de Sèze"'
Autor:
Jonathan Ciron, Bertrand Bourre, Giovanni Castelnovo, Anne Marie Guennoc, Jérôme De Sèze, Ali Frederic Ben-Amor, Carine Savarin, Patrick Vermersch
Publikováno v:
Neurology and Therapy, Vol 13, Iss 3, Pp 503-518 (2024)
Abstract Cladribine tablets (CladT) has been available for therapeutic use in France since March 2021 for the management of highly active relapsing multiple sclerosis (RMS). This high-efficacy disease-modifying therapy (DMT) acts as an immune reconst
Externí odkaz:
https://doaj.org/article/06f16c9074374b3a8dfa5f9b1a3fe96d
Autor:
Romain Marignier, David Laplaud, Hélène Zéphir, Caroline Papeix, Emmanuelle Leray, Ekbel Amri, Mickaël Piotaix, Jérôme de Sèze
Publikováno v:
Frontiers in Neurology, Vol 14 (2024)
BackgroundEculizumab, a humanized monoclonal antibody targeting the C5 complement protein, has been approved for the treatment of neuromyelitis optica spectrum disorders (NMOSD) in adult patients who are anti-aquaporin-4 (AQP4) antibody positive (Ab+
Externí odkaz:
https://doaj.org/article/b3394019b11c4a9381e06cbcc5c767e6
Autor:
Jérôme de Sèze, Elisabeth Maillart, Antoine Gueguen, David A. Laplaud, Laure Michel, Eric Thouvenot, Hélène Zephir, Luc Zimmer, Damien Biotti, Roland Liblau
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The immune system plays a significant role in multiple sclerosis. While MS was historically thought to be T cell-mediated, multiple pieces of evidence now support the view that B cells are essential players in multiple sclerosis pathogenic processes.
Externí odkaz:
https://doaj.org/article/6c1151d42f3841f1bdb01bd757830364
Publikováno v:
Immuno, Vol 2, Iss 1, Pp 118-131 (2022)
Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired immune-mediated inflammatory disorder of the peripheral nervous system. This clinically heterogeneous neurological disorder is closely related to Guillain–Barré syndrome and i
Externí odkaz:
https://doaj.org/article/2aedc468855e42ad85d7b4da05a12cd3
Autor:
Sarah Wilson, Floriane Calocer, Fabien Rollot, Mathieu Fauvernier, Laurent Remontet, Laure Tron, Sandra Vukusic, Emmanuelle Le Page, Marc Debouverie, Jonathan Ciron, Aurélie Ruet, Jérôme De Sèze, Hélène Zephir, Thibault Moreau, Christine Lebrun-Frénay, David-Axel Laplaud, Pierre Clavelou, Pierre Labauge, Eric Berger, Jean Pelletier, Olivier Heinzlef, Eric Thouvenot, Jean Philippe Camdessanché, Emmanuelle Leray, Olivier Dejardin, Gilles Defer
Publikováno v:
The Lancet Regional Health. Europe, Vol 24, Iss , Pp 100542- (2023)
Summary: Background: The effects of socio-economic status on mortality in patients with multiple sclerosis is not well known. The objective was to examine mortality due to multiple sclerosis according to socio-economic status. Methods: A retrospectiv
Externí odkaz:
https://doaj.org/article/ed163a351a914b918dd49d51d455ef33
Autor:
Maria Pia Sormani, Marco Salvetti, Pierre Labauge, Irene Schiavetti, Helene Zephir, Luca Carmisciano, Caroline Bensa, Nicola De Rossi, Jean Pelletier, Cinzia Cordioli, Sandra Vukusic, Lucia Moiola, Philippe Kerschen, Marta Radaelli, Marie Théaudin, Paolo Immovilli, Olivier Casez, Marco Capobianco, Jonathan Ciron, Maria Trojano, Bruno Stankoff, Alain Créange, Gioacchino Tedeschi, Pierre Clavelou, Giancarlo Comi, Eric Thouvenot, Mario Alberto Battaglia, Thibault Moreau, Francesco Patti, Jérôme De Sèze, Celine Louapre, the Musc‐, the Covisep study groups
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 8, Pp 1738-1744 (2021)
Abstract We evaluated the effect of DMTs on Covid‐19 severity in patients with MS, with a pooled‐analysis of two large cohorts from Italy and France. The association of baseline characteristics and DMTs with Covid‐19 severity was assessed by mu
Externí odkaz:
https://doaj.org/article/dc03cd08037d4f2191d0b6ce786e866a
Autor:
Audrey Gauthier, Sébastien Viel, Magali Perret, Guillaume Brocard, Romain Casey, Christine Lombard, Sabine Laurent‐Chabalier, Marc Debouverie, Gilles Edan, Sandra Vukusic, Christine Lebrun‐Frénay, Jérôme De Sèze, David Axel Laplaud, Giovanni Castelnovo, Olivier Gout, Aurélie Ruet, Thibault Moreau, Olivier Casez, Pierre Clavelou, Eric Berger, Hélène Zephir, Sophie Trouillet‐Assant, Eric Thouvenot, OFSEP Investigators
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 5, Pp 1141-1150 (2021)
Abstract We compared SimoaTM and EllaTM immunoassays to assess serum neurofilament‐light chain levels in 203 multiple sclerosis patients from the OFSEP HD study. There was a strong correlation (ρ = 0.86, p
Externí odkaz:
https://doaj.org/article/065e81b4c5174e9fa867174580f930de
Autor:
Youssef El Khoury, Marie Gebelin, Jérôme de Sèze, Christine Patte-Mensah, Gilles Marcou, Alexandre Varnek, Ayikoé-Guy Mensah-Nyagan, Petra Hellwig, Nicolas Collongues
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2791 (2022)
Neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) are both autoimmune inflammatory and demyelinating diseases of the central nervous system. NMOSD is a highly disabling disease and rapid introduction of the appropriate treatm
Externí odkaz:
https://doaj.org/article/849f9468f3114c0783948847d4c058ef
Autor:
Kévin Bigaut, Sophie Achard, Céline Hemmert, Seyyid Baloglu, Laurent Kremer, Nicolas Collongues, Jérôme De Sèze, Stéphane Kremer
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211465 (2019)
BACKGROUND:The relation between brain functional connectivity of patients with neuromyelitis optica spectrum disorder (NMOSD) and the degree of disability remains unclear. OBJECTIVE:Compare brain functional connectivity of patients with NMOSD to heal
Externí odkaz:
https://doaj.org/article/7e501019d283418991599b1e8c3bf2b0
Autor:
Valérie Jolivel, Susana Brun, Fabien Binamé, Jérémie Benyounes, Omar Taleb, Dominique Bagnard, Jérôme De Sèze, Christine Patte-Mensah, Ayikoe-Guy Mensah-Nyagan
Publikováno v:
Cells, Vol 10, Iss 3, p 698 (2021)
Microglial cells are key players in neural pathogenesis and microglial function regulation appears to be pivotal in controlling neuroinflammatory/neurological diseases. Here, we investigated the effects and mechanism of action of neurosteroid allopre
Externí odkaz:
https://doaj.org/article/56041ace58d848b0b70fecb739a9e217