Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Jérôme Ruel"'
Autor:
Anissa Rym Saidia, Florence François, François Casas, Ilana Mechaly, Stéphanie Venteo, Joseph T. Veechi, Jérôme Ruel, Jean-Luc Puel, Jing Wang
Publikováno v:
Antioxidants, Vol 13, Iss 2, p 149 (2024)
The disruption of the synaptic connection between the sensory inner hair cells (IHCs) and the auditory nerve fiber terminals of the type I spiral ganglion neurons (SGN) has been observed early in several auditory pathologies (e.g., noise-induced or o
Externí odkaz:
https://doaj.org/article/2d39b64836784478ae6dc8b6e4031a8e
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 3, p 738 (2023)
Auditory neuropathy spectrum disorder (ANSD) refers to a range of hearing impairments characterized by an impaired transmission of sound from the cochlea to the brain. This defect can be due to a lesion or defect in the inner hair cell (IHC), IHC rib
Externí odkaz:
https://doaj.org/article/c5ae0e9582e444adba989ae1e85e1883
Autor:
Jing Wang, Nicolas Serratrice, Cindy J. Lee, Florence François, Jonathan V. Sweedler, Jean-Luc Puel, Jean-Pierre Mothet, Jérôme Ruel
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
NMDA receptors (NMDARs) populate the complex between inner hair cell (IHC) and spiral ganglion neurons (SGNs) in the developing and mature cochlea. However, in the mature cochlea, activation of NMDARs is thought to mainly occur under pathological con
Externí odkaz:
https://doaj.org/article/3409046475464ae5bdf29b96a242f73e
Autor:
Caroline Bonnet, Jizhe Hao, Nancy Osorio, Anne Donnet, Virginie Penalba, Jérôme Ruel, Patrick Delmas
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The precise mechanisms that lead to medication-overuse headaches (MOH), which can occur with both over-the-counter and prescription pain-relief medicines, are still uncertain. In this study, authors show that the abnormal activation of dural nocicept
Externí odkaz:
https://doaj.org/article/13bb724449b94f508ae02468f5087389
Autor:
Jérôme Ruel, Matthieu J. Guitton, Paul Gratias, Marc Lenoir, Sanbing Shen, Jean-Luc Puel, Philippe Brabet, Jing Wang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Pituitary adenylyl cyclase-activating polypeptide (PACAP) is a member of the vasoactive intestinal polypeptide (VIP)-the secretin-glucagon family of neuropeptides. They act through two classes of receptors: PACAP type 1 (PAC1) and type 2 (VPAC1 and V
Externí odkaz:
https://doaj.org/article/fb1c3c219f4446ea9e62abbc1c4503dc
Autor:
Caroline Bonnet, Jizhe Hao, Nancy Osorio, Anne Donnet, Virginie Penalba, Jérôme Ruel, Patrick Delmas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/d9e44aa553dd45cabdef69d8f444a987
Autor:
Stéphane Lolignier, Caroline Bonnet, Christelle Gaudioso, Jacques Noël, Jérôme Ruel, Muriel Amsalem, Jérémy Ferrier, Lise Rodat-Despoix, Valentine Bouvier, Youssef Aissouni, Laetitia Prival, Eric Chapuy, Françoise Padilla, Alain Eschalier, Patrick Delmas, Jérôme Busserolles
Publikováno v:
Cell Reports, Vol 11, Iss 7, Pp 1067-1078 (2015)
Cold-triggered pain is essential to avoid prolonged exposure to harmfully low temperatures. However, the molecular basis of noxious cold sensing in mammals is still not completely understood. Here, we show that the voltage-gated Nav1.9 sodium channel
Externí odkaz:
https://doaj.org/article/b41660b502d941c294543319bb5331b1
Autor:
Antoine Jouvenel, Adrien Tassou, Maxime Thouaye, Jérôme Ruel, Myriam Antri, Jean-Philippe Leyris, Aurore Paquet, Sylvie Mallié, Chamroeum Sar, Lucie Diouloufet, Corinne Sonrier, François Daubeuf, Juliette Bertin, Stacy Alves, Stéphanie Ventéo, Nelly Frossard, Patrick Carroll, Ilana Mechaly, Didier Rognan, Pierre Sokoloff, Radhouane Dallel, Patrick Delmas, Jean Valmier, Cyril Rivat
Opioid analgesia is counteracted on chronic use by tolerance and hyperalgesia inducing dose escalation and life-threatening overdoses. Mu opiate receptors (MOR) expressed in primary sensory neurons were recently found to control tolerance and hyperal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c8034c8ff982ad6b4eac00671207050
https://doi.org/10.1101/2023.03.16.532971
https://doi.org/10.1101/2023.03.16.532971
Autor:
Jizhe, Hao, Lucie, Brosse, Caroline, Bonnet, Myriam, Ducrocq, Françoise, Padilla, Virginie, Penalba, Angélique, Desplat, Jérôme, Ruel, Patrick, Delmas
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 35(12)
Mepyramine, a first-generation antihistamine targeting the histamine H(1) receptor, was extensively prescribed to patients suffering from allergic reactions and urticaria. Serious adverse effects, especially in case of overdose, were frequently repor
Autor:
Paola Principe, Virginie Penalba, Myriam Ducrocq, Séverine Hatton, Patrick Delmas, Jérôme Ruel, Camille Petitfils, Gilles Dietrich, Céline Greco, Anne-Laure Genevois
Publikováno v:
The Journal of Pain
The Journal of Pain, 2021, 22 (4), pp.440-453. ⟨10.1016/j.jpain.2020.11.002⟩
The Journal of Pain, 2021, 22 (4), pp.440-453. ⟨10.1016/j.jpain.2020.11.002⟩
International audience; Oral amitriptyline hydrochloride (amitriptyline) is ineffective against some forms of chronic pain and is often associated with dose-limiting adverse events. We evaluated the potential effectiveness of high-dose topical amitri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a486a29f11f3dea5fd086fd5fd6a0e3
https://hal.inrae.fr/hal-03084518/document
https://hal.inrae.fr/hal-03084518/document