Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jérôme P. Fennell"'
Publikováno v:
BMC Infectious Diseases, Vol 16, Iss 1, Pp 1-7 (2016)
Abstract Background The prevalence of urinary tract infections (UTIs) caused by extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae is increasing and the therapeutic options are limited, especially in primary care. Recent indications h
Externí odkaz:
https://doaj.org/article/067b0ed6b9e14e6691d135fc051f9617
Autor:
Rustom P. Manecksha, Gregory J. Nason, Ivor M. Cullen, Jérôme P. Fennell, Elizabeth McEvoy, Ted McDermott, Robert J. Flynn, Ronald Grainger, John A. Thornhill
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
We aimed to compare infection rates for two 3-day antibiotic prophylaxis regimens for transrectal ultrasound-guided prostate biopsy (TRUSgbp) and demonstrate local microbiological trends. In 2008, 558 men and, in 2009, 625 men had TRUSgpb. Regimen 1
Externí odkaz:
https://doaj.org/article/97f304968a7248009bb895690d9a841e
Autor:
Aisling F Brown, Alison G Murphy, Stephen J Lalor, John M Leech, Kate M O'Keeffe, Micheál Mac Aogáin, Dara P O'Halloran, Keenan A Lacey, Mehri Tavakol, Claire H Hearnden, Deirdre Fitzgerald-Hughes, Hilary Humphreys, Jérôme P Fennell, Willem J van Wamel, Timothy J Foster, Joan A Geoghegan, Ed C Lavelle, Thomas R Rogers, Rachel M McLoughlin
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005226 (2015)
Mechanisms of protective immunity to Staphylococcus aureus infection in humans remain elusive. While the importance of cellular immunity has been shown in mice, T cell responses in humans have not been characterised. Using a murine model of recurrent
Externí odkaz:
https://doaj.org/article/6832261a8fdf4af4abe77367d6c1163a
Autor:
Gillian Sexton, Nicola Kavanagh, Jérôme P. Fennell, Sadhbh O'Rourke, Steven W. Kerrigan, Fergal J. O'Brien, Emily J. Ryan, Amro Widaa, Cathal J. Kearney, Kevin C. Cahill
Publikováno v:
Clinical Microbiology Reviews. 31
SUMMARY Osteomyelitis is an inflammatory bone disease that is caused by an infecting microorganism and leads to progressive bone destruction and loss. The most common causative species are the usually commensal staphylococci, with Staphylococcus aure
Autor:
Mazen Alsinnawi, Emma Groarke, Eddie McCullagh, Robert Flynn, Ronald Grainger, Jérôme P. Fennell, Sean Egan, Ted McDermott, John A. Thornhill
Publikováno v:
Current Urology. 8:175-177
We assessed patients who had pre-operative urine that grew gentamicin-resistant bacteria but were given gentamicin prophylaxis because urine result was not available. Our aim was to identify postoperative-sepsis rates, risk factors to acquire resista
Autor:
Jason A. Roberts, Philomena O'Byrne, Johnny McHugh, Jérôme P. Fennell, Brett McWhinney, Deirdre M. D’Arcy, Evelyn Deasy, Sheila A. Ryder, Catherine J. Byrne, Ted Parton, Sean Egan, Helen Enright, Ronan Desmond
Publikováno v:
The Journal of antimicrobial chemotherapy. 73(4)
To develop a pharmacokinetic model describing total and unbound teicoplanin concentrations in patients with haematological malignancy and to perform Monte Carlo simulations to evaluate target attainment of unbound trough concentrations with various d
Autor:
Sean Egan, Deirdre M. D’Arcy, Evelyn Deasy, Helen Enright, Sheila A. Ryder, Jérôme P. Fennell, Johnny McHugh, Philomena O'Byrne, Catherine J. Byrne
Publikováno v:
European Journal of Hospital Pharmacy. 21:301-305
Objective To investigate current practices with teicoplanin in patients with haematological malignancy in centres throughout the UK and Ireland with respect to indication for usage and timing of introduction in febrile neutropenia, dosage regimens an
Autor:
Sheila A. Ryder, Brett McWhinney, Philomena O'Byrne, Jason A. Roberts, Evelyn Deasy, Sean Egan, Jérôme P. Fennell, Helen Enright, Johnny McHugh, Ronan Desmond, Catherine J. Byrne, Deirdre M. D’Arcy
Publikováno v:
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 23(9)
Objectives To describe the population pharmacokinetics of teicoplanin in adult patients with haematological malignancies receiving higher than standard doses, and to perform Monte Carlo simulations to determine dosing regimens associated with optimal
Autor:
Catherine J. Byrne, Evelyn Deasy, Philomena O'Byrne, Jason A. Roberts, Sheila A. Ryder, Johnny McHugh, Brett McWhinney, Deirdre M. D’Arcy, Jérôme P. Fennell, Ronan Desmond, Sean Egan, Helen Enright
Publikováno v:
Antimicrobial agents and chemotherapy. 61(6)
The objective of this study was to explore the following aspects of teicoplanin use in patients with hematological malignancy: early attainment of target trough concentrations with current high-dose teicoplanin regimens, variability in unbound teicop
Publikováno v:
BMC Infectious Diseases
BMC Infectious Diseases, Vol 16, Iss 1, Pp 1-7 (2016)
BMC Infectious Diseases, Vol 16, Iss 1, Pp 1-7 (2016)
Background The prevalence of urinary tract infections (UTIs) caused by extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae is increasing and the therapeutic options are limited, especially in primary care. Recent indications have sugge