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pro vyhledávání: '"Jérôme M. B. Durand"'
Autor:
Jérôme M. B. Durand, Glenn R. Björk
Publikováno v:
Microbiology. 155:2498-2508
This paper shows that compounds in defined growth media strongly influence the expression of the effectors of virulence in the human invasive pathogenShigella flexneri. Ornithine in conjunction with uracil reduces the haemolytic ability of wild-type
Autor:
Samia Sn Ben Salem, Jérôme M. B. Durand, Philip J. Farabaugh, Guillaume Stahl, Jaunius Urbonavičius, Qiang Q Qian, Glenn R. Björk
Using mutants (tgt, mnmA(asuE, trmU), mnmE(trmE), miaA, miaB, miaE, truA(hisT), truB) of either Escherichia coli or Salmonella enterica serovar Typhimurium and the trm5 mutant of Saccharomyces cerevisiae, we have analyzed the influence by the modifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47978d64a51388a5fe0001cdab5cc02f
https://europepmc.org/articles/PMC1370442/
https://europepmc.org/articles/PMC1370442/
Autor:
Jérôme M B, Durand, Glenn R, Björk
Publikováno v:
Molecular microbiology. 47(2)
The wild-type strain YSH6000 of Shigella flexneri growing in minimal medium contains the modified nucleoside epoxy-Q (oQ) in a subset of tRNAs. This nucleoside is lacking in tRNA from a tgt mutant of this bacterium. When these bacteria are growing in
The modified nucleosides 2′- O -methylguanosine, present at position 18 (Gm18), 5-methyluridine, present at position 54 (m 5 U54), and pseudouridine, present at position 55 (Ψ55), are located in the D and T arms of tRNAs and are close in space in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83ba7200577951d291bd760d8d54e5d
https://europepmc.org/articles/PMC135347/
https://europepmc.org/articles/PMC135347/
Publikováno v:
The EMBO journal. 20(17)
Transfer RNAs from all organisms contain many modified nucleosides. Their vastly different chemical structures, their presence in different tRNAs, their occurrence in different locations in tRNA and their influence on different reactions in which tRN
Publikováno v:
Molecular microbiology. 35(4)
Full expression of the virulence genes of Shigella flexneri requires the presence of two modified nucleosides in the tRNA [queuosine, Q34, present in the wobble position (position 34) and 2-methylthio-N6-isopentenyladenosine (ms2i6A37, adjacent to an
Publikováno v:
Journal of bacteriology. 179(18)
The virulence of the human pathogen Shigella flexneri is dependent on both chromosome- and large-virulence-plasmid-encoded genes. A kanamycin resistance cassette mutation in the miaA gene (miaA::Km Sma), which encodes the tRNA N6-isopentyladenosine (
Autor:
Tord G. Hagervall, Qiang Qian, Hans K. Lundgren, Peng Chen, Jaunius Urbonavičius, Jérôme M. B. Durand, Glenn R. Björk, Kristina Nilsson, Ramun≐ Leipuvien≐
Publikováno v:
FEBS Letters. (1-2):47-51
Transfer RNA modification improves the rate of aa-tRNA selection at the A-site and the fitness in the P-site and thereby prevents frameshifting according to a new model how frameshifting occurs [Qian et al. (1998) Mol. Cell 1, 471–482]. Evidence th