Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jérôme Jacq"'
Autor:
James R. Frost, Julien Brown, Jean-Paul Kestemont, Jérôme Jacq, Patrick Pasau, Frédéric Perl, Matthieu Tissot
Publikováno v:
Organic Process Research & Development. 26:635-639
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67f6132f49ebe6ce2e4f665dc1634c4c
https://doi.org/10.1021/acs.oprd.1c00092
https://doi.org/10.1021/acs.oprd.1c00092
Publikováno v:
Organic Process Research & Development. 24:802-806
We report an amination of mesylated cyclobutanol enabled by a multistep continuous flow process. The flow sequence involved an azidation followed by a Staudinger reduction which avoids the handling...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14831feb360689846a9e0b426b52a33c
https://doi.org/10.1021/acs.oprd.9b00381
https://doi.org/10.1021/acs.oprd.9b00381
Publikováno v:
Angewandte Chemie. 130:10857-10861
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da4ad033ceb04bdf0e9865746cd043e2
https://doi.org/10.1002/ange.201804628
https://doi.org/10.1002/ange.201804628
Autor:
Christophe Genicot, Jérôme Jacq, Maurice van Gastel, Frank Neese, Jiakun Li, Gregory B. Boursalian, Jannik C. Borghs, Jeffrey A. O. Garber, Julian David Rolfes, Tobias Ritter, Kumiko Yamamoto
Publikováno v:
Nature. 554:511-514
Aryl fluorides are widely used in the pharmaceutical and agrochemical industries, and recent advances have enabled their synthesis through the conversion of various functional groups. However, there is a lack of general methods for direct aromatic ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0270609d159d6c528f1fbcd47b26ee91
https://doi.org/10.1038/nature25749
https://doi.org/10.1038/nature25749
Autor:
Ricardo Labes, Claudio Battilocchio, Steven V. Ley, Christophe Genicot, Jérôme Jacq, Mathieu Lesieur, Patrick Pasau
Publikováno v:
Chemistry – A European Journal.
A fast, scalable, and safer Csp3 -H oxidation of activated and un-activated aliphatic chains can be enabled by methyl(trifluoromethyl)dioxirane (TFDO). The continuous flow platform allows the in situ generation of TFDO gas and its rapid reactivity to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6822408c3b7bbec9d06ec4273a52e0
https://doi.org/10.1002/chem.201805657
https://doi.org/10.1002/chem.201805657
Publikováno v:
Angewandte Chemie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e29f214e5b521cfbc390640e46fe9a52
https://doi.org/10.1002/ange.201810262
https://doi.org/10.1002/ange.201810262
Publikováno v:
Advanced Synthesis & Catalysis. 358:3422-3434
The modification of benzylic quaternary, tertiary, and secondary carbon centers through palladium-catalyzed hydrogenolysis of C(sp3)–C(sp3) σ bonds is presented. When benzyl Meldrum's acid derivatives bearing quaternary benzylic centers are treate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a976fcc532de67df7db29c58b202c474
https://doi.org/10.1002/adsc.201600535
https://doi.org/10.1002/adsc.201600535
Autor:
Mathieu, Lesieur, Claudio, Battilocchio, Ricardo, Labes, Jérôme, Jacq, Christophe, Genicot, Steven V, Ley, Patrick, Pasau
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 25(5)
A fast, scalable, and safer C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e09b85aedf5a39f06ca04330046f876a
https://pubmed.ncbi.nlm.nih.gov/30485562
https://pubmed.ncbi.nlm.nih.gov/30485562
Publikováno v:
Angewandte Chemie (International ed. in English). 57(33)
A selective, nonchelation-assisted methylation of arenes has been developed. The overall transformation, which combines a C-H functionalization reaction with a nickel-catalyzed cross-coupling, offers rapid access to methylated arenes with high para s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8f9ff32d745fcc4366758ce4eedbc26
https://pubmed.ncbi.nlm.nih.gov/29893494
https://pubmed.ncbi.nlm.nih.gov/29893494
Autor:
Patrick Pasau, Jérôme Jacq
Publikováno v:
Chemistry - A European Journal. 20:12223-12233
1,2,3-Triazole has become one of the most important heterocycles in contemporary medicinal chemistry. The development of the copper-catalyzed Huisgen cycloaddition has allowed the efficient synthesis of 1-substituted 1,2,3-triazoles. However, only a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279e03ea6882df1335aa6ebb2ae82f00
https://doi.org/10.1002/chem.201402074
https://doi.org/10.1002/chem.201402074