Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jérôme Dayer"'
Autor:
Fabian Bickel, François Griaud, Wolfram Kern, Frieder Kroener, Manuela Gritsch, Jérôme Dayer, Samuel Barteau, Blandine Denefeld, Chi-Ya Kao-Scharf, Manuel Lang, Izabela Slupska-Muanza, Carla Schmidt, Matthias Berg, Jürgen Sigg, Lina Boado, Dirk Chelius
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTIn this study, we report the isomerization of an aspartic acid residue in the complementarity-determining region (CDR) of crizanlizumab as a major degradation pathway. The succinimide intermediate and iso-aspartic acid degradation products we
Externí odkaz:
https://doaj.org/article/704ad1576cf945d7aab734d00191b085
Autor:
Fabian Bickel, François Griaud, Wolfram Kern, Frieder Kroener, Manuela Gritsch, Jérôme Dayer, Samuel Barteau, Blandine Denefeld, Chi-Ya Kao-Scharf, Manuel Lang, Izabela Slupska-Muanza, Carla Schmidt, Matthias Berg, Jürgen Sigg, Lina Boado, Dirk Chelius
Publikováno v:
mAbs. 15(1)
In this study, we report the isomerization of an aspartic acid residue in the complementarity-determining region (CDR) of crizanlizumab as a major degradation pathway. The succinimide intermediate and iso-aspartic acid degradation products were succe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991c52a12578df74020d0adbe884e91a
https://pubmed.ncbi.nlm.nih.gov/36519228
https://pubmed.ncbi.nlm.nih.gov/36519228