Alzheimer disease pathology and the cerebrospinal fluid proteome

Autor: Loïc Dayon, Antonio Núñez Galindo, Jérôme Wojcik, Ornella Cominetti, John Corthésy, Aikaterini Oikonomidi, Hugues Henry, Martin Kussmann, Eugenia Migliavacca, India Severin, Gene L. Bowman, Julius Popp

Publikováno v: Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2018)

Abstract Background Altered proteome profiles have been reported in both postmortem brain tissues and body fluids of subjects with Alzheimer disease (AD), but their broad relationships with AD pathology, amyloid pathology, and tau-related neurodegene

Externí odkaz: https://doaj.org/article/5a300155e9c6438b9f6a17f924c566a5

Single Nucleotide Polymorphism Clustering in Systemic Autoimmune Diseases.

Autor: Thomas Charlon, Manuel Martínez-Bueno, Lara Bossini-Castillo, F David Carmona, Alessandro Di Cara, Jérôme Wojcik, Sviatoslav Voloshynovskiy, Javier Martín, Marta E Alarcón-Riquelme

Publikováno v: PLoS ONE, Vol 11, Iss 8, p e0160270 (2016)

Systemic Autoimmune Diseases, a group of chronic inflammatory conditions, have variable symptoms and difficult diagnosis. In order to reclassify them based on genetic markers rather than clinical criteria, we performed clustering of Single Nucleotide

Externí odkaz: https://doaj.org/article/7b1e72d9caf04eab9a1887589e435aff

Pharmacodynamic biomarkers of long-term interferon beta-1a therapy in REFLEX and REFLEXION

Autor: Kristina H. Holmberg, Mauro D'Antonio, Sofia Stinchi, Vittorio D'Urso, Yann Hyvert, Fernando Dangond, Jérôme Wojcik, Mark S. Freedman, Markus Fluck

Publikováno v: Journal of Neuroimmunology. 360:577715

This post-hoc analysis evaluated candidate biomarkers of long-term efficacy of subcutaneous interferon beta-1a (sc IFN β-1a) in REFLEX/REFLEXION studies of clinically isolated syndrome. Samples from 507 REFLEX and 287 REFLEXION study participants we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d4746f5183c99232fbe059fddf7451
https://doi.org/10.1016/j.jneuroim.2021.577715

Protective effects of rimeporide on left ventricular function in golden retriever muscular dystrophy dogs

Autor: Bijan Ghaleh, Inès Barthélémy, Luc Hittinger, Jérôme Wojcik, Stéphane Blot, Alain Bizé, Thien Duc Tran, Jin Bo Su, Lucien Sambin, Florence Porte Thomé

Publikováno v: International Journal of Cardiology
International Journal of Cardiology, Elsevier, 2020, 312, pp.89-95. ⟨10.1016/j.ijcard.2020.03.031⟩

Background Alterations in intracellular Na+ and Ca2+ have been observed in patients with Duchenne muscular dystrophy (DMD) and in animal models of DMD, and inhibition of Na+-H+ exchanger 1 (NHE1) by rimeporide has previously demonstrated cardioprotec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a828a6fc62f42c64afa4cd7548c32563
https://pubmed.ncbi.nlm.nih.gov/32504721

Alzheimer disease pathology and the cerebrospinal fluid proteome

Autor: Jérôme Wojcik, Aikaterini Oikonomidi, John Corthésy, Antonio Núñez Galindo, Gene L. Bowman, India Severin, Ornella Cominetti, Julius Popp, Loïc Dayon, Martin Kussmann, Hugues Henry, Eugenia Migliavacca

Publikováno v: Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2018)
Alzheimer's Research & Therapy
Alzheimer's research & therapy, vol. 10, no. 1, pp. 66

Background Altered proteome profiles have been reported in both postmortem brain tissues and body fluids of subjects with Alzheimer disease (AD), but their broad relationships with AD pathology, amyloid pathology, and tau-related neurodegeneration ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3cb91840bd5d639f44e286352ad06f
https://doi.org/10.1186/s13195-018-0397-4