Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Jérôme, Toutain"'
Autor:
Carole Brunaud, Samuel Valable, Gwenn Ropars, Fatima-Azzahra Dwiri, Mikaël Naveau, Jérôme Toutain, Myriam Bernaudin, Thomas Freret, Marianne Léger, Omar Touzani, Elodie A. Pérès
Publikováno v:
Cancer Imaging, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Radiotherapy is a major therapeutic approach in patients with brain tumors. However, it leads to cognitive impairments. To improve the management of radiation-induced brain sequalae, deformation-based morphometry (DBM) could be re
Externí odkaz:
https://doaj.org/article/77fd6275a3c2446d9a90183a3d776331
Autor:
Jérôme Levallet, Tiphaine Biojout, Céline Bazille, Manon Douyère, Fatéméh Dubois, Dimitri Leite Ferreira, Jasmine Taylor, Sylvain Teulier, Jérôme Toutain, Nicolas Elie, Myriam Bernaudin, Samuel Valable, Emmanuel Bergot, Guénaëlle Levallet
Publikováno v:
Cell Death and Disease, Vol 14, Iss 12, Pp 1-13 (2023)
Abstract The molecular mechanisms induced by hypoxia are misunderstood in non-small cell lung cancer (NSCLC), and above all the hypoxia and RASSF1A/Hippo signaling relationship. We confirmed that human NSCLC (n = 45) as their brain metastases (BM) co
Externí odkaz:
https://doaj.org/article/314a3a44fb5749b79b75d1af5f9ad218
Autor:
Jade Fantin, Jérôme Toutain, Elodie A. Pérès, Benoit Bernay, Sarina Maya Mehani, Charly Helaine, Mickael Bourgeois, Carole Brunaud, Laurent Chazalviel, Julien Pontin, Aurélien Corroyer-Dulmont, Samuel Valable, Michel Cherel, Myriam Bernaudin
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Background Brain metastases (BM) are the most frequent malignant brain tumors. The aim of this study was to characterize the tumor microenvironment (TME) of BM and particularly hypoxia and redox state, known to play a role in tumor growth an
Externí odkaz:
https://doaj.org/article/44a54d68b7284a3a8692b762391858b1
Autor:
Aurélien Corroyer-Dulmont, Samuel Valable, Jade Fantin, Laurent Chatre, Jérôme Toutain, Sylvain Teulier, Céline Bazille, Elise Letissier, Jérôme Levallet, Didier Divoux, Méziane Ibazizène, Stéphane Guillouet, Cécile Perrio, Louisa Barré, Sébastien Serres, Nicola R. Sibson, Françoise Chapon, Guénaëlle Levallet, Myriam Bernaudin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Lung cancer patients frequently develop brain metastases (BM). Despite aggressive treatment including neurosurgery and external-radiotherapy, overall survival remains poor. There is a pressing need to further characterize factors in the micr
Externí odkaz:
https://doaj.org/article/ee453995c9c84f099bc393bb803de626
Autor:
Elodie A. Pérès, Jérôme Toutain, Louis-Paul Paty, Didier Divoux, Méziane Ibazizène, Stéphane Guillouet, Louisa Barré, Aurélien Vidal, Michel Cherel, Mickaël Bourgeois, Myriam Bernaudin, Samuel Valable
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-15 (2019)
Abstract Background Diacetyl-bis(N4-methylthiosemicarbazone), labeled with 64Cu (64Cu-ATSM) has been suggested as a promising tracer for imaging hypoxia. However, various controversial studies highlighted potential pitfalls that may disable its use a
Externí odkaz:
https://doaj.org/article/e90ccfff5e35401c9889fec7302f79d4
Autor:
Grégoire Cullot, Julian Boutin, Jérôme Toutain, Florence Prat, Perrine Pennamen, Caroline Rooryck, Martin Teichmann, Emilie Rousseau, Isabelle Lamrissi-Garcia, Véronique Guyonnet-Duperat, Alice Bibeyran, Magalie Lalanne, Valérie Prouzet-Mauléon, Béatrice Turcq, Cécile Ged, Jean-Marc Blouin, Emmanuel Richard, Sandrine Dabernat, François Moreau-Gaudry, Aurélie Bedel
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
CRISPR-Cas9 has been rapidly adopted to generate cell line models of disease. Here the authors show, while attempting to establish a congenital erythropoietic porphyria model, unexpected chromosome truncations generated by a p53-dependent mechanism.
Externí odkaz:
https://doaj.org/article/3a225f969b444010a97c3369c573fb50
Autor:
Andrey Postnov, Jérôme Toutain, Igor Pronin, Samuel Valable, Fabienne Gourand, Diana Kalaeva, Nina Vikhrova, Elena Pyzhik, Stéphane Guillouet, Grigoriy Kobyakov, Ekaterina Khokholova, David Pitskhelauri, Dmitry Usachev, Sergey Maryashev, Marina Rizhova, Alexander Potapov, Jean-Michel Derlon
Publikováno v:
Clinical Nuclear Medicine. 47:699-706
This study sought to assess 18 F-fludarabine ( 18 F-FLUDA) PET/CT's ability in differentiating primary central nervous system lymphomas (PCNSLs) from glioblastoma multiformes (GBMs).Patients harboring either PCNSL (n = 8) before any treatment, PCNSL
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195905 (2018)
We wanted to re-evaluate the influence of confined placental mosaicism subtypes (type 2 and type 3) on pregnancy characteristics and outcome.From July 2009 to December 2015, 5512 chorionic villus samplings were performed in our Fetal Medicine Center.
Externí odkaz:
https://doaj.org/article/6f3d44b2990e49e4a5a459ebdc8631ff
Autor:
Samuel Valable, Jérôme Toutain, Didier Divoux, Laurent Chazalviel, Aurélien Corroyer‐Dulmont, Ararat Chakhoyan, Stéphane Guillouet, Myriam Bernaudin, Emmanuel L. Barbier, Omar Touzani
Publikováno v:
NMR in biomedicineREFERENCES.
Acute ischemic stroke results in an ischemic core surrounded by a tissue at risk, named the penumbra, which is potentially salvageable. One way to differentiate the tissues is to measure the hypoxia status. The purpose of the current study is to corr
Autor:
Julie Coupey, Jérôme Toutain, Erika HUE, Hélaine, C., Jade Richard, Romaric Saulnier, Chazalviel Laurent, Marc Rousseau, Juliette Thariat, Valable Samuel, Leblond, M. M.
Publikováno v:
46th Annual Meeting of the European Radiation Research Society (ERRS 2021)
46th Annual Meeting of the European Radiation Research Society (ERRS 2021), Nov 2021, Caen, France
“Adaptation of the tumour and its ecosystem to radiotherapies“ workshop (14th CGO)
“Adaptation of the tumour and its ecosystem to radiotherapies“ workshop (14th CGO), Sep 2021, Le Bono, France
HAL
46th Annual Meeting of the European Radiation Research Society (ERRS 2021), Nov 2021, Caen, France.
46th Annual Meeting of the European Radiation Research Society (ERRS 2021), Nov 2021, Caen, France
“Adaptation of the tumour and its ecosystem to radiotherapies“ workshop (14th CGO)
“Adaptation of the tumour and its ecosystem to radiotherapies“ workshop (14th CGO), Sep 2021, Le Bono, France
HAL
46th Annual Meeting of the European Radiation Research Society (ERRS 2021), Nov 2021, Caen, France.
CERVOXY; International audience; Although conventional radiotherapy based on X-rays improves brain tumour patient survival, it also leads to deleterious effects on the inflammatory component: enrichment of pro-tumour macrophages1 as well as recruitme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cd04643baa367beb87a57f58fee99801
https://hal-normandie-univ.archives-ouvertes.fr/hal-03444552
https://hal-normandie-univ.archives-ouvertes.fr/hal-03444552