Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jérôme, Biton"'
Autor:
Diane Damotte, Sarah Warren, Jennifer Arrondeau, Pascaline Boudou-Rouquette, Audrey Mansuet-Lupo, Jérôme Biton, Hanane Ouakrim, Marco Alifano, Claire Gervais, Audrey Bellesoeur, Nora Kramkimel, Camille Tlemsani, Barbara Burroni, Angéline Duche, Franck Letourneur, Han Si, Rebecca Halpin, Todd Creasy, Ronald Herbst, Xing Ren, Pascale Morel, Alessandra Cesano, François Goldwasser, Karen Leroy
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background The 18-gene tumor inflammation signature (TIS) is a clinical research assay that enriches for clinical benefit to immune checkpoint blockade. We evaluated its ability to predict clinical benefit of immunotherapy in cancer patients
Externí odkaz:
https://doaj.org/article/b75c5fd83d2d4639a48bed140c36dd2f
Autor:
Claire Germain, Priyanka Devi-Marulkar, Samantha Knockaert, Jérôme Biton, Hélène Kaplon, Laïla Letaïef, Jérémy Goc, Agathe Seguin-Givelet, Dominique Gossot, Nicolas Girard, Pierre Validire, Marine Lefèvre, Diane Damotte, Marco Alifano, François M. Lemoine, Keith E. Steele, Jean-Luc Teillaud, Scott A. Hammond, Marie-Caroline Dieu-Nosjean
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The presence of tertiary lymphoid structures (TLS) in the tumor microenvironment is associated with better clinical outcome in many cancers. In non-small cell lung cancer (NSCLC), we have previously showed that a high density of B cells within TLS (T
Externí odkaz:
https://doaj.org/article/757b1a291fa64d989f66f304930a5ace
Autor:
Diane Damotte, Hélène Blons, Ronald Herbst, Isabelle Cremer, Marie-Caroline Dieu-Nosjean, Pierre Laurent-Puig, Claire Germain, Marie Wislez, Jeremy Goc, Karen Leroy, François Goldwasser, Pascaline Boudou-Rouquette, Jennifer Arrondeau, Hanane Ouakrim, Marco Alifano, Nicolas Pécuchet, Audrey Mansuet-Lupo, Jérôme Biton
Purpose: By unlocking antitumor immunity, antibodies targeting programmed cell death 1 (PD-1) exhibit impressive clinical results in non–small cell lung cancer, underlining the strong interactions between tumor and immune cells. However, factors th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be9933892cb63e1e90c325d91851c84
https://doi.org/10.1158/1078-0432.c.6527516
https://doi.org/10.1158/1078-0432.c.6527516
Autor:
Diane Damotte, Hélène Blons, Ronald Herbst, Isabelle Cremer, Marie-Caroline Dieu-Nosjean, Pierre Laurent-Puig, Claire Germain, Marie Wislez, Jeremy Goc, Karen Leroy, François Goldwasser, Pascaline Boudou-Rouquette, Jennifer Arrondeau, Hanane Ouakrim, Marco Alifano, Nicolas Pécuchet, Audrey Mansuet-Lupo, Jérôme Biton
Figures S1-12 Tables S1-S4 Supplementary material Supplementary Table S1. Antibodies used in flow cytometry experiments. Supplementary Table S2. Baseline characteristics of the 221 patients with lung adenocarcinoma in each TIP. Supplementary Table S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1793e050c7a3a699dad8917392d81e61
https://doi.org/10.1158/1078-0432.22470311
https://doi.org/10.1158/1078-0432.22470311
Autor:
Véronique M. Braud, Jérôme Biton, Etienne Becht, Samantha Knockaert, Audrey Mansuet-Lupo, Estelle Cosson, Diane Damotte, Marco Alifano, Pierre Validire, Fabienne Anjuère, Isabelle Cremer, Nicolas Girard, Dominique Gossot, Agathe Seguin-Givelet, Marie-Caroline Dieu-Nosjean, Claire Germain
Publikováno v:
OncoImmunology, Vol 7, Iss 5 (2018)
Co-stimulatory and inhibitory receptors expressed by immune cells in the tumor microenvironment modulate the immune response and cancer progression. Their expression and regulation are still not fully characterized and a better understanding of these
Externí odkaz:
https://doaj.org/article/164e7738449c4dea95192ede491c7aff
Publikováno v:
Joint Bone Spine
Joint Bone Spine, Elsevier Masson, 2020, 87, pp.301-306. ⟨10.1016/j.jbspin.2019.11.009⟩
Joint Bone Spine, 2020, 87, pp.301-306. ⟨10.1016/j.jbspin.2019.11.009⟩
Joint Bone Spine, Elsevier Masson, 2020, 87, pp.301-306. ⟨10.1016/j.jbspin.2019.11.009⟩
Joint Bone Spine, 2020, 87, pp.301-306. ⟨10.1016/j.jbspin.2019.11.009⟩
While the exact cause of rheumatoid arthritis is unknown, several mechanisms have been described extensively. The genetic predisposition for this autoimmune disease is largely attributed to MHC class II genes, especially the main polymorphism in the
Autor:
Hanane Ouakrim, P Morel, Angéline Duché, Marco Alifano, Diane Damotte, Pascaline Boudou-Rouquette, Camille Tlemsani, Sarah Warren, Jérôme Biton, Alessandra Cesano, Rebecca Halpin, Claire Gervais, Nora Kramkimel, Han Si, Jennifer Arrondeau, Todd Creasy, Audrey Bellesoeur, Barbara Burroni, Ronald Herbst, Franck Letourneur, Xing Ren, Audrey Mansuet-Lupo, Karen Leroy, François Goldwasser
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Journal of Translational Medicine
Journal of Translational Medicine
Background The 18-gene tumor inflammation signature (TIS) is a clinical research assay that enriches for clinical benefit to immune checkpoint blockade. We evaluated its ability to predict clinical benefit of immunotherapy in cancer patients treated
Publikováno v:
Revue du Rhumatisme. 86:A19-A24
RESUME On ne connait pas la cause de la polyarthrite rhumatoide, mais on en connait bien de tres nombreux mecanismes. Confirmant le caractere auto-immun de la maladie, le terrain genetique est largement domine par les genes HLA de classe II, surtout
Autor:
Marco Alifano, Audrey Mansuet-Lupo, Filippo Lococo, Nicolas Roche, Antonio Bobbio, Emelyne Canny, Olivier Schussler, Hervé Dermine, Jean-François Régnard, Barbara Burroni, Jérémy Goc, Jérôme Biton, Hanane Ouakrim, Isabelle Cremer, Marie-Caroline Dieu-Nosjean, Diane Damotte
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106914 (2014)
BACKGROUND: Hypothesizing that nutritional status, systemic inflammation and tumoral immune microenvironment play a role as determinants of lung cancer evolution, the purpose of this study was to assess their respective impact on long-term survival i
Externí odkaz:
https://doaj.org/article/7662a0c46d9348c682c0e56940b15335
Publikováno v:
Revue du Rhumatisme. 85:529-535
Resume La pollution est incriminee dans un grand nombre de pathologies respiratoires et cardiovasculaires. Plus recemment, le role des particules issues de la pollution a ete etudie dans les maladies auto-immunes et en particulier dans la polyarthrit