Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jérémy Reniers"'
Publikováno v:
European Journal of Organic Chemistry. 2015:1472-1484
A general method for the preparation of galactose derivatives locked in a 1,4B boat conformation has been developed. The boat scaffold was stereoselectively functionalized at the C-1′ position by aliphatic and aromatic groups along with azido or hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae773185e877ccb0c5a984297a24ada2
https://doi.org/10.1002/ejoc.201403363
https://doi.org/10.1002/ejoc.201403363
Autor:
Johan Wouters, Bernard Masereel, Moreno Galleni, Eduard Dolusic, Jérémy Reniers, Sophie Laurent, Raphaël Frédérick, Laurence Moineaux, Jean-Marie Frère
Publikováno v:
Moineaux, L, Laurent, S, Reniers, J, Dolusic, E, Galleni, M, Frère, J-M, Masereel, B, Frédérick, R & Wouters, J 2012, ' Synthesis, crystal structures and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles ', European Journal of Medicinal Chemistry, vol. 54, pp. 95-102 . https://doi.org/10.1016/j.ejmech.2012.04.033
Three isomers of chloro-3-(2-pyridin-3-ylvinyl)-1H-indole were synthesized and tested as inhibitors of human tryptophan 2,3-dioxygenase (hTDO). The crystal structures of two of them were solved by X-ray diffraction. The solubility of the molecules al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba7a053224523f33ca708daa241db21
https://researchportal.unamur.be/en/publications/686d2f59-2592-476d-b6c3-630e827725db
https://researchportal.unamur.be/en/publications/686d2f59-2592-476d-b6c3-630e827725db
Autor:
Jérémy Reniers, Raphaël Frédérick, Laurence Moineaux, Stéphane P. Vincent, Céline Meinguet, Bernard Masereel, Johan Wouters
Publikováno v:
European Journal of Medicinal Chemistry. 46:6104-6111
Previous studies on 5H-indeno[1,2-c]pyridazin-5-one derivatives as inhibitors of MAO-B revealed that it was possible to increase the MAO-B inhibitory potency of 5H-indeno[1,2-c]pyridazin-5-ones by substituting the central heterocycle in the 3-positio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf839801d1f5ed6653477ac38b56c04b
https://doi.org/10.1016/j.ejmech.2011.09.042
https://doi.org/10.1016/j.ejmech.2011.09.042
Autor:
Jérémy Reniers, Bernard Masereel, Stéphane P. Vincent, Johan Wouters, Raphaël Frédérick, Séverine Robert
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:134-144
Previous studies have shown that harmine is a reversible inhibitor of human monoamine oxidase A (MAO-A). Moreover, the crystal structure of human MAO-A in complex with harmine has been recently solved. This crystal structure shows that close to the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f867f5b44b3c663cc4abfe2754ab0a17
https://doi.org/10.1016/j.bmc.2010.11.041
https://doi.org/10.1016/j.bmc.2010.11.041
Autor:
Johan Wouters, Raphaël Frédérick, Laurence Moineaux, Bernard Masereel, Jérémy Reniers, Stéphane P. Vincent, Céline Meinguet
Publikováno v:
ChemInform. 43
New 5H-indeno[1,2-c]pyridazines are synthesized and their inhibitory potency against human monoamine oxidase (MOA) A and B is evaluated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2f98d9a46e63e7714ae7df86889a2d3
https://doi.org/10.1002/chin.201214162
https://doi.org/10.1002/chin.201214162
Autor:
Christelle Vancraeynest, Jérémy Reniers, Lionel Pochet, Céline Meinguet, Raphaël Frédérick, Robert Kiss, Bernard Masereel, Anders Backlund, Johan Wouters, Céline Bruyère
Publikováno v:
Journal of Medicinal Chemistry, Vol. 55, no. 14, p. 6489-6501 (2012)
To overcome the intrinsic resistance of cancer cells to apoptotic stimuli, we designed and synthesized approximately 50 novel β-carbolines structurally related to harmine. Harmine is known for its anticancer properties and is a DYRK1A inhibitor. Of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe1e882bf43c9a8ef111850192297ff
https://hdl.handle.net/2078.1/162942
https://hdl.handle.net/2078.1/162942
