Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jérémie Topin"'
Autor:
Jody Pacalon, Guillaume Audic, Justine Magnat, Manon Philip, Jérôme Golebiowski, Christophe J. Moreau, Jérémie Topin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract In numerous insects, the olfactory receptor family forms a unique class of heteromeric cation channels. Recent progress in resolving the odorant receptor structures offers unprecedented opportunities for deciphering their molecular mechanism
Externí odkaz:
https://doaj.org/article/b16c6ce639bb4d078a61f12fc07040fb
Autor:
Jody Pacalon, Guillaume Audic, Justine Magnat, Manon Philip, Jérôme Golebiowski, Christophe J. Moreau, Jérémie Topin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/a80750c91a5646799883b05b39867f03
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Systematic enrichments of l-amino acids in meteorites is a strong indication that biological homochirality originated beyond Earth. Although still unresolved, stellar UV circularly polarized light (CPL) is the leading hypothesis to have caus
Externí odkaz:
https://doaj.org/article/6136b92c94f144b2a2c940068e19441c
Autor:
Cornelia Meinert, Adrien D. Garcia, Jérémie Topin, Nykola C. Jones, Mira Diekmann, Robert Berger, Laurent Nahon, Søren V. Hoffmann, Uwe J. Meierhenrich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)
Chiroptical properties of amino acids are challenging to investigate in the gas phase due to the low vapor pressure of these molecules. Here the authors succeed in measuring circular dichroism active transitions and anisotropies in the ultraviolet ra
Externí odkaz:
https://doaj.org/article/2dcdf39bf0444112a526e501556bde04
Publikováno v:
Biology, Vol 12, Iss 1, p 2 (2022)
Odorant-binding proteins (OBPs) are abundant soluble proteins secreted in the nasal mucus of a variety of species that are believed to be involved in the transport of odorants toward olfactory receptors. In this study, we report the functional charac
Externí odkaz:
https://doaj.org/article/e1c2f55337524478ac528c5dd468e9e3
Autor:
Tammy Shim, Jody Pacalon, Won-Cheol Kim, Xiaojing Cong, Jérémie Topin, Jérôme Golebiowski, Cheil Moon
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12501 (2022)
Mammals recognize chemicals in the air via G protein-coupled odorant receptors (ORs). In addition to their orthosteric binding site, other segments of these receptors modulate ligand recognition. Focusing on human hOR1A1, which is considered prototyp
Externí odkaz:
https://doaj.org/article/2b785d74e6b24a4b96cedd461b7f2948
Autor:
Jody Pacalon, Guillaume Audic, Justine Magnat, Manon Philip, Jérôme Golebiowski, Christophe J. Moreau, Jérémie Topin
In numerous insects, the olfactory receptor family forms a unique class of heteromeric cation channels. Recent progress in resolving the odorant receptor structures offers unprecedented opportunities for deciphering their molecular mechanisms of liga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b5fdafdba81e38b54d6a9f68c9c4328
https://doi.org/10.1101/2023.05.05.539596
https://doi.org/10.1101/2023.05.05.539596
Autor:
Mee-Ra Rhyu, Sébastien Fiorucci, Jérôme Golebiowski, Jérémie Topin, Yi-Seul Kim, Jody Pacalon, Cédric Bouysset
Publikováno v:
Cellular and Molecular Life Sciences. 78:7605-7615
Bitter taste receptors (TAS2Rs) are a poorly understood subgroup of G protein-coupled receptors (GPCRs). The experimental structure of these receptors has yet to be determined, and key-residues controlling their function remain mostly unknown. We des
Autor:
Yiqun Yu, Jody Pacalon, Zhenjie Ma, Xiaojing Cong, Jérôme Golebiowski, Lun Xu, Christine Belloir, Loïc Briand, Jérémie Topin
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, 2022, 298 (9), pp.102331. ⟨10.1016/j.jbc.2022.102331⟩
Journal of Biological Chemistry, 2022, 298 (9), pp.102331. ⟨10.1016/j.jbc.2022.102331⟩
International audience; G protein-coupled olfactory receptors (ORs) enable us to detect innumerous odorants. They are also ectopically expressed in non-olfactory tissues and emerging as attractive drug targets. ORs can be promiscuous or highly specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3054d35dfbf1c5f41d8c66b776cea6
https://doi.org/10.1101/2021.10.26.465980
https://doi.org/10.1101/2021.10.26.465980
Autor:
Annabelle Varrot, Priscila da Silva Figueiredo Celestino Gomes, Anne Imberty, Sakonwan Kuhaudomlarp, Jérémie Topin, Eike Siebs, Christoph Rademacher, Elena Shanina, Ines Joachim, Didier Rognan, Alexander Titz
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2021, 60 (15), pp.8104-8114. ⟨10.1002/anie.202013217⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2021, ⟨10.1002/anie.202013217⟩
Angewandte Chemie
Angewandte Chemie (International ed. in English)
Germany
Angewandte Chemie (International Ed. in English)
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2021, 60 (15), pp.8104-8114. ⟨10.1002/anie.202013217⟩
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2021, ⟨10.1002/anie.202013217⟩
Angewandte Chemie
Angewandte Chemie (International ed. in English)
Germany
Angewandte Chemie (International Ed. in English)
Because of the antimicrobial resistance crisis, lectins are considered novel drug targets. Pseudomonas aeruginosa utilizes LecA and LecB in the infection process. Inhibition of both lectins with carbohydrate‐derived molecules can reduce biofilm for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a834ee46ba3ed3629e37b15a6c56dc8
https://hal.archives-ouvertes.fr/hal-03266505
https://hal.archives-ouvertes.fr/hal-03266505