Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jérémie Ménager"'
Autor:
Jean-Baptiste Gorin, Jérémie Ménager, Sébastien Gouard, Catherine Maurel, Yannick Guilloux, Alain Faivre-Chauvet, Alfred Morgenstern, Frank Bruchertseifer, Michel Chérel, François Davodeau, Joëlle Gaschet
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 4, Pp 319-328 (2014)
Radioimmunotherapy (RIT) is a therapeutic modality that allows delivering of ionizing radiation directly to targeted cancer cells. Conventional RIT uses β-emitting radioisotopes, but recently, a growing interest has emerged for the clinical developm
Externí odkaz:
https://doaj.org/article/256472fb83534cd293b09b0b436d237a
Autor:
Jérémie Ménager, Jean-Baptiste Gorin, Catherine Maurel, Lucile Drujont, Sébastien Gouard, Cédric Louvet, Michel Chérel, Alain Faivre-Chauvet, Alfred Morgenstern, Frank Bruchertseifer, François Davodeau, Joëlle Gaschet, Yannick Guilloux
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130249 (2015)
Ionizing radiation induces direct and indirect killing of cancer cells and for long has been considered as immunosuppressive. However, this concept has evolved over the past few years with the demonstration that irradiation can increase tumor immunog
Externí odkaz:
https://doaj.org/article/b3759baf927d447e88b80403dbb76309
Autor:
Jérémie Ménager, Frédéric Ebstein, Romain Oger, Philippe Hulin, Steven Nedellec, Eric Duverger, Andrea Lehmann, Peter-Michael Kloetzel, Francine Jotereau, Yannick Guilloux
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89897 (2014)
Antitumor vaccination using synthetic long peptides (SLP) is an additional therapeutic strategy currently under development. It aims to activate tumor-specific CD8(+) CTL by professional APCs such as DCs. DCs can activate T lymphocytes by MHC class I
Externí odkaz:
https://doaj.org/article/ba13189aea0549fea425c64f16b41f73
Autor:
Marc Gregoire, Jean-François Fonteneau, Frédéric Tangy, Chantal Combredet, Jérémie Ménager, David Roulois, Nicolas Boisgerault, Jean-Baptiste Guillerme
PDF file - 214K, Supplemental Figure 6: Monocyte-derived DC exhibit a similar level of NYESO-1 cross-presentation compared to pDC. (A) on day0, pDC and monocytes from a single donor were purified. pDC were frozen and monocytes cultured with IL-4 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5556d7bedad0954f85a16b17067271d8
https://doi.org/10.1158/1078-0432.22448754.v1
https://doi.org/10.1158/1078-0432.22448754.v1
Autor:
Marc Gregoire, Jean-François Fonteneau, Frédéric Tangy, Chantal Combredet, Jérémie Ménager, David Roulois, Nicolas Boisgerault, Jean-Baptiste Guillerme
PDF file - 92K, Supplemental Figure 5: shematic of the culture conditions used in the cross-presentation experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12093e0c976d1924b332370fb39fad64
https://doi.org/10.1158/1078-0432.22448757
https://doi.org/10.1158/1078-0432.22448757
Autor:
Marc Gregoire, Jean-François Fonteneau, Frédéric Tangy, Chantal Combredet, Jérémie Ménager, David Roulois, Nicolas Boisgerault, Jean-Baptiste Guillerme
AVI file - 14040K, Supplemental Figure 1: infection of the mesothelioma cell line Meso13 by MV-eGFP. Meso13 mesothelioma cell line was cocultured 2 hours with MV-eGFP and then washed (MOI=1). Sixteen hours later, fluorescence microscopy video was per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d310d56b1db6e27d85fe005b2c57da
https://doi.org/10.1158/1078-0432.22448772.v1
https://doi.org/10.1158/1078-0432.22448772.v1
Autor:
Marc Gregoire, Jean-François Fonteneau, Frédéric Tangy, Chantal Combredet, Jérémie Ménager, David Roulois, Nicolas Boisgerault, Jean-Baptiste Guillerme
Purpose: Plasmacytoid dendritic cells (pDC) are antigen-presenting cells specialized in antiviral response. The measles virus vaccine is proposed as an antitumor agent to target and specifically kill tumor cells without infecting healthy cells.Experi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89557fb8a4d2ebc1a55e34bc06a37792
https://doi.org/10.1158/1078-0432.c.6521478.v1
https://doi.org/10.1158/1078-0432.c.6521478.v1
Autor:
Marc Gregoire, Jean-François Fonteneau, Frédéric Tangy, Chantal Combredet, Jérémie Ménager, David Roulois, Nicolas Boisgerault, Jean-Baptiste Guillerme
PDF file - 223K, Supplemental Figure 4: Activation of pDC in response to MV-infected tumor cells is independent of MV replication in pDC and infection by CD46. (A) pDC were cultured with IL-3 alone, R848, IL-3/MV-eGFP (MV), IL-3/MV-eGFP with 10mg/ml
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf923ae04bb75241a6dbf58a5aa804ed
https://doi.org/10.1158/1078-0432.22448760
https://doi.org/10.1158/1078-0432.22448760
Autor:
Marc Gregoire, Jean-François Fonteneau, Frédéric Tangy, Chantal Combredet, Jérémie Ménager, David Roulois, Nicolas Boisgerault, Jean-Baptiste Guillerme
PDF file - 115K, Supplemental figure 3: Infection of pDC by MV-eGFP or UV-irradiated MV-eGFP: pDC in presence of IL-3 or Meso13 cells were cultured alone (NI) or with MV-eGFP (MV) or UV-irradiated (312nm - 100kj/m�) MV-eGFP (MV*) at MOI=50 during 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823adcc1ccac360038a794375430b0a3
https://doi.org/10.1158/1078-0432.22448763.v1
https://doi.org/10.1158/1078-0432.22448763.v1
Autor:
Jérémie, Ménager, Jean-Baptiste, Gorin, Nolwenn, Fichou, Sébastien, Gouard, Alfred, Morgenstern, Frank, Bruchertseifer, François, Davodeau, Françoise, Kraeber-Bodéré, Michel, Chérel, Joëlle, Gaschet, Yannick, Guilloux
Publikováno v:
Medecine sciences : M/S. 32(4)
Alpha-radioimmunotherapy (α-RIT) is a targeted anti-tumor therapy using usually a monoclonal antibody specific for a tumor antigen that is coupled to an α-particle emitter. α-emitters represent an ideal tool to eradicate disseminated tumors or met