Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jérémie Bourdon"'
Publikováno v:
BMC Bioinformatics, Vol 24, Iss S1, Pp 1-24 (2023)
Abstract Background The impact of a perturbation, over-expression, or repression of a key node on an organism, can be modelled based on a regulatory and/or metabolic network. Integration of these two networks could improve our global understanding of
Externí odkaz:
https://doaj.org/article/d85e8a1499c34b71862e4f166076ac15
Autor:
Stéphanie Kilens, Dimitri Meistermann, Diego Moreno, Caroline Chariau, Anne Gaignerie, Arnaud Reignier, Yohann Lelièvre, Miguel Casanova, Céline Vallot, Steven Nedellec, Léa Flippe, Julie Firmin, Juan Song, Eric Charpentier, Jenna Lammers, Audrey Donnart, Nadège Marec, Wallid Deb, Audrey Bihouée, Cédric Le Caignec, Claire Pecqueur, Richard Redon, Paul Barrière, Jérémie Bourdon, Vincent Pasque, Magali Soumillon, Tarjei S. Mikkelsen, Claire Rougeulle, Thomas Fréour, Laurent David, The Milieu Intérieur Consortium
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Derivation of human induced pluripotent stem cells (hiPSCs) produces primed hiPSCs that can in turn be converted to naive hiPSCs. Here, the authors directly reprogram somatic cells to form both naive and primed isogenic hiPSCs and confirm the similar
Externí odkaz:
https://doaj.org/article/99050a32ab984d7caf964c0d03730743
Autor:
Damien Eveillard, Nicholas J. Bouskill, Damien Vintache, Julien Gras, Bess B. Ward, Jérémie Bourdon
Publikováno v:
Frontiers in Microbiology, Vol 9 (2019)
Understanding the interactions between microbial communities and their environment sufficiently to predict diversity on the basis of physicochemical parameters is a fundamental pursuit of microbial ecology that still eludes us. However, modeling micr
Externí odkaz:
https://doaj.org/article/5f97867a7a27491c83ff1434c9145b3a
Publikováno v:
Informatics, Vol 7, Iss 1, p 1 (2020)
The integration of high-throughput data to build predictive computational models of cellular metabolism is a major challenge of systems biology. These models are needed to predict cellular responses to genetic and environmental perturbations. Typical
Externí odkaz:
https://doaj.org/article/e84a4ddb2c11415a85e16b0bce6ee14c
Autor:
Misbah Razzaq, Loïc Paulevé, Anne Siegel, Julio Saez-Rodriguez, Jérémie Bourdon, Carito Guziolowski
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 10, p e1006538 (2018)
Protein signaling networks are static views of dynamic processes where proteins go through many biochemical modifications such as ubiquitination and phosphorylation to propagate signals that regulate cells and can act as feed-back systems. Understand
Externí odkaz:
https://doaj.org/article/dd641583953a42aba07201dfa4230365
Autor:
Sylvain Prigent, Clémence Frioux, Simon M Dittami, Sven Thiele, Abdelhalim Larhlimi, Guillaume Collet, Fabien Gutknecht, Jeanne Got, Damien Eveillard, Jérémie Bourdon, Frédéric Plewniak, Thierry Tonon, Anne Siegel
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 1, p e1005276 (2017)
Increasing amounts of sequence data are becoming available for a wide range of non-model organisms. Investigating and modelling the metabolic behaviour of those organisms is highly relevant to understand their biology and ecology. As sequences are of
Externí odkaz:
https://doaj.org/article/518f2f7b9e27497bb380d0c30d680027
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171744 (2017)
Interplay within microbial communities impacts ecosystems on several scales, and elucidation of the consequent effects is a difficult task in ecology. In particular, the integration of genome-scale data within quantitative models of microbial ecosyst
Externí odkaz:
https://doaj.org/article/61369731de664ab5a07974fcf0a0329c
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 9, p e1002157 (2011)
Despite recent improvements in molecular techniques, biological knowledge remains incomplete. Any theorizing about living systems is therefore necessarily based on the use of heterogeneous and partial information. Much current research has focused su
Externí odkaz:
https://doaj.org/article/7439fc2eea3d4f42908ae0327f2a58eb
Autor:
Jérémie Bourdon, Alban Mancheron
Publikováno v:
Discrete Mathematics & Theoretical Computer Science, Vol DMTCS Proceedings vol. AG,..., Iss Proceedings (2006)
In computational biology, a large amount of problems, such as pattern discovery, deals with the comparison of several sequences (of nucleotides, proteins or genes for instance). Very often, algorithms that address this problem use score functions tha
Externí odkaz:
https://doaj.org/article/da304c1c9ac5452284502db11a779175
Autor:
Loïc Campion, Catherine Guérin-Charbonnel, Stephane Minvielle, Victor Gaborit, Jennifer Derrien, Jérémie Bourdon, P. Moreau, Carl Herrmann, Nathalie Roi, Jonathan Cruard, Elise Douillard, Florence Magrangeas, Magali Devic, Jean-Baptiste Alberge, Frank Westermann
Glucocorticoids (GC) effects occur through binding to the GC receptor (GR) which, once translocated to the nucleus, binds to GC response elements (GREs) to activate or repress target genes. Among GCs, dexamethasone (Dex) is widely used in treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27362dc0d11d485800ff9269e8300ab
https://doi.org/10.1101/2021.09.06.459068
https://doi.org/10.1101/2021.09.06.459068
