Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Jérémie, Canonica"'
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Akademický článek
Delineating effects of angiopoietin-2 inhibition on vascular permeability and inflammation in models of retinal neovascularization and ischemia/reperfusion
Autor: Jérémie Canonica, Richard Foxton, Marina Garcia Garrido, Cheng-Mao Lin, Sabine Uhles, Sumathi Shanmugam, David A. Antonetti, Steven F. Abcouwer, Peter D. Westenskow
Publikováno v: Frontiers in Cellular Neuroscience, Vol 17 (2023)
IntroductionClinical trials demonstrated that co-targeting angiopoietin-2 (Ang-2) and vascular endothelial growth factor (VEGF-A) with faricimab controls anatomic outcomes and maintains vision improvements, with strong durability, through 2 years in
Externí odkaz: https://doaj.org/article/eb987d4d51b2489f96e27b6a29635f5b
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2
Akademický článek
Mineralocorticoid receptor antagonism limits experimental choroidal neovascularization and structural changes associated with neovascular age-related macular degeneration
Autor: Min Zhao, Irmela Mantel, Emmanuelle Gelize, Xinxin Li, Xiaoyue Xie, Alejandro Arboleda, Marie Seminel, Rinath Levy-Boukris, Marilyn Dernigoghossian, Andrea Prunotto, Charlotte Andrieu-Soler, Carlo Rivolta, Jérémie Canonica, Marie-Christine Naud, Sebastian Lechner, Nicolette Farman, Irene Bravo-Osuna, Rocio Herrero-Vanrell, Frederic Jaisser, Francine Behar-Cohen
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Current treatments for age-related neovascular macular degeneration (nAMD) suffer from limited efficacy. Here, Zhao et al. show that pharmacological inhibition or genetic deletion of the mineralocorticoid receptor (MR) limits choroidal neovascularisa
Externí odkaz: https://doaj.org/article/38bef37aaba649d6a6734776e59801e9
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3
Akademický článek
Lack of Renal Tubular Glucocorticoid Receptor Decreases the Thiazide-Sensitive Na+/Cl– Cotransporter NCC and Transiently Affects Sodium Handling
Autor: Jérémie Canonica, Simona Frateschi, Emilie Boscardin, Anna Ebering, Chloé Sergi, Yannick Jäger, Thibaud Peyrollaz, Anne-Marie Mérillat, Marc Maillard, Petra Klusonova, Alex Odermatt, Robert Koesters, Anne Debonneville, Olivier Staub, Sophia N. Verouti, Edith Hummler
Publikováno v: Frontiers in Physiology, Vol 10 (2019)
Chronic glucocorticoid infusion impairs NCC activity and induces a non-dipping profile in mice, suggesting that glucocorticoids are essential for daily blood pressure variations. In this paper, we studied mice lacking the renal tubular glucocorticoid
Externí odkaz: https://doaj.org/article/94cec7ac22974ea5b7e7c6c28a09bae4
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4
Preventing VEGF-Mediated Vascular Permeability by Experimentally Potentiating BBB Characteristics in Endothelial Cells
Autor: Bo Kyoung, Kim, Jérémie, Canonica, Filip, Roudnicky, Peter D, Westenskow
Publikováno v: Methods in molecular biology (Clifton, N.J.). 2475
Difficulties with poor reproducibility and translatability of animal model-based research, along with increased efforts to abide by the 3Rs tenet of animal welfare, are driving demand for more relevant human cellular systems. This is especially true
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::67be0daab426bfc13950528f70ea1143
https://pubmed.ncbi.nlm.nih.gov/35451764
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7
Pathogenic Effects of Mineralocorticoid Pathway Activation in Retinal Pigment Epithelium
Autor: Justine Guegan, Min Zhao, Emmanuelle Gelize, Say Viengchareun, Laura Kowalczuk, Francine Behar-Cohen, Yvan Arsenijevic, Tatiana Favez, Jérémie Canonica, Eric Pussard, Marc Lombès, Damien Le Menuet, Laurent Jonet
Publikováno v: International journal of molecular sciences, vol. 22, no. 17, pp. 9618
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2021, 22 (17), pp.9618. ⟨10.3390/ijms22179618⟩
International Journal of Molecular Sciences, MDPI, 2021, 22 (17), pp.9618. ⟨10.3390/ijms22179618⟩
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9618, p 9618 (2021)
Glucocorticoids are amongst the most used drugs to treat retinal diseases of various origins. Yet, the transcriptional regulations induced by glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) activation in retinal pigment epithelium ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b214e7ef257b84e81d6c0b3f003c2936
https://serval.unil.ch/resource/serval:BIB_29FED9B83112.P001/REF.pdf
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8
Critical role of the mineralocorticoid receptor in aldosterone-dependent and aldosterone-independent regulation of ENaC in the distal nephron
Autor: Jérémie Canonica, Paul A. Welling, Christoph Korbmacher, Edith Hummler, Viatcheslav Nesterov, Marko Bertog, Richard Coleman
Publikováno v: Am J Physiol Renal Physiol
The epithelial Na(+) channel (ENaC) constitutes the rate-limiting step for Na(+) absorption in the aldosterone-sensitive distal nephron (ASDN) comprising the late distal convoluted tubule (DCT2), connecting tubule (CNT), and collecting duct (CD). Pre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5d8ce99393b40d6b4890c67c84028a
https://europepmc.org/articles/PMC9847332/
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9
Meteorin Is a Novel Therapeutic Target for Wet Age-Related Macular Degeneration
Autor: Min Zhao, Alexandre Moulin, Marie-Christine Naud, Virginie Dinet, Jérémie Canonica, Francine Behar-Cohen, Patricia Crisanti-Lassiaz, Alexandre Sellam, Kimberley Delaunay, Emmanuelle Gelize
Publikováno v: Journal of Clinical Medicine
Journal of Clinical Medicine, 2021, 10 (13), pp.2973. ⟨10.3390/jcm10132973⟩
Journal of clinical medicine, vol. 10, no. 13, pp. 2973
Journal of Clinical Medicine, MDPI, 2021, 10 (13), pp.2973. ⟨10.3390/jcm10132973⟩
Journal of Clinical Medicine, Vol 10, Iss 2973, p 2973 (2021)
Volume 10
Issue 13
International audience; The aim of this study was to evaluate the potential anti-angiogenic effect of MTRN (meteorin) in the laser-induced CNV rat model and explore its mechanisms of action. MTRN, thrompospondin-1, glial cell markers (GFAP, vimentin)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f65b665bb3026523c6cf0b261ab43d
https://hal.sorbonne-universite.fr/hal-03291983
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