Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations

Autor: Criswell, Lindsey, Wang, C, Ahlford, A, Järvinen, TM, Nordmark, G, Eloranta, ML, Gunnarsson, I, Svenungsson, E, Padyukov, L, Sturfelt, G, Jönsen, A

Publikováno v: Criswell, Lindsey; Wang, C; Ahlford, A; Järvinen, TM; Nordmark, G; Eloranta, ML; et al.(2013). Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/4232g8rs

Recent genome-wide association studies (GWASs) conducted in Asian populations have identified novel risk loci for systemic lupus erythematosus (SLE). Here, we genotyped 10 single-nucleotide polymorphisms (SNPs) in eight such loci and investigated the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::77e89da8c703dca50168d99ce7ee5312
http://www.escholarship.org/uc/item/4232g8rs

Observational evidence from patients diagnosed with chronic lymphocytic leukaemia (CLL) in Finland between 2005-2015 show improved survival over time.

Autor: Lindström V; Department of Hematology, Helsinki University Hospital Comprehensive Cancer Center and University of Helsinki, Helsinki, Finland., Hakkarainen KM; StatFinn & EPID Research, Gothenburg, Sweden., Mehtälä J; StatFinn & EPID Research, Espoo, Finland., Klement R; StatFinn & EPID Research, Tartu, Estonia., Leval A; Janssen-Cilag Ab, Solna, Sweden., Järvinen TM; Janssen-Cilag Oy, Espoo, Finland.

Publikováno v: European journal of haematology [Eur J Haematol] 2019 Sep; Vol. 103 (3), pp. 190-199. Date of Electronic Publication: 2019 Jul 25.

Somatic MED12 mutations are associated with poor prognosis markers in chronic lymphocytic leukemia.

Autor: Kämpjärvi K; Department of Medical Genetics and Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland., Järvinen TM; Department of Molecular Virology, Immunology and Medical Genetics, Division of Human Cancer Genetics, Comprehensive Cancer Center at The Ohio State University, Columbus, OH, USA., Heikkinen T; Department of Medical Genetics and Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland., Ruppert AS; Department of Internal Medicine, Division of Hematology, Comprehensive Cancer Center at The Ohio State University, Columbus, OH, USA., Senter L; Department of Molecular Virology, Immunology and Medical Genetics, Division of Human Cancer Genetics, Comprehensive Cancer Center at The Ohio State University, Columbus, OH, USA., Hoag KW; Department of Molecular Virology, Immunology and Medical Genetics, Division of Human Cancer Genetics, Comprehensive Cancer Center at The Ohio State University, Columbus, OH, USA., Dufva O; Department of Medical Genetics and Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland., Kontro M; Hematology Research Unit Helsinki, Department of Medicine, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland., Rassenti L; Moores University of California-San Diego Cancer Center, University of California San Diego, CA, USA., Hertlein E; Department of Internal Medicine, Division of Hematology, Comprehensive Cancer Center at The Ohio State University, Columbus, OH, USA., Kipps TJ; Moores University of California-San Diego Cancer Center, University of California San Diego, CA, USA., Porkka K; Hematology Research Unit Helsinki, Department of Medicine, Helsinki University Central Hospital and University of Helsinki, Helsinki, Finland., Byrd JC; Department of Internal Medicine, Division of Hematology, Comprehensive Cancer Center at The Ohio State University, Columbus, OH, USA., de la Chapelle A; Department of Molecular Virology, Immunology and Medical Genetics, Division of Human Cancer Genetics, Comprehensive Cancer Center at The Ohio State University, Columbus, OH, USA., Vahteristo P; Department of Medical Genetics and Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland.

Publikováno v: Oncotarget [Oncotarget] 2015 Jan 30; Vol. 6 (3), pp. 1884-8.

Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population.

Autor: Järvinen TM; Department of Biosciences and Nutrition, Karolinska Institutet, Hälsovägen 7-9, S-14183 Huddinge, Sweden., Hellquist A, Zucchelli M, Koskenmies S, Panelius J, Hasan T, Julkunen H, D'Amato M, Kere J

Publikováno v: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2012 Jan; Vol. 51 (1), pp. 87-92. Date of Electronic Publication: 2011 Oct 27.

Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosus.

Autor: Järvinen TM; Department of Dermatology, Institute of Clinical Medicine and Biomedicum Helsinki, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Hellquist A, Koskenmies S, Einarsdottir E, Panelius J, Hasan T, Julkunen H, Padyukov L, Kvarnström M, Wahren-Herlenius M, Nyberg F, D'Amato M, Kere J, Saarialho-Kere U

Publikováno v: PloS one [PLoS One] 2010 Dec 02; Vol. 5 (12), pp. e14212. Date of Electronic Publication: 2010 Dec 02.