Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms

Autor: Bahhir, Diana, Yalgin, Cagri, Ots, Liina, Järvinen, Sampsa, George, Jack, Naudí, Alba, Krama, Tatjana, Krams, Indrikis, Tamm, Mairi, Andjelković, Ana, Dufour, Eric, González de Cózar, Jose M., Gerards, Mike, Parhiala, Mikael, Pamplona, Reinald, Jacobs, Howard T., Jõers, Priit

Publikováno v: PLoS Genetics, Vol 15, Iss 10, p e1008410 (2019)
Recercat. Dipósit de la Recerca de Catalunya
instname
Plos Genetics, 15(10):1008410. Public Library of Science
Repositorio Abierto de la UdL
Universitad de Lleida
PLoS Genetics

Mitochondria have been increasingly recognized as a central regulatory nexus for multiple metabolic pathways, in addition to ATP production via oxidative phosphorylation (OXPHOS). Here we show that inducing mitochondrial DNA (mtDNA) stress in Drosoph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5de8a281886509c4249a2d126e20d80a
https://doaj.org/article/c367ecdb264e415a939fdddc23efbe38

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