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of 873
pro vyhledávání: '"Järvelin, MR"'
Autor:
Gormley, P, Anttila, V, Winsvold, BS, Palta, P, Esko, T, Pers, TH, Farh, KH, Cuenca-Leon, E, Muona, M, Furlotte, NA, Kurth, T, Ingason, A, McMahon, G, Ligthart, L, Terwindt, GM, Kallela, M, Freilinger, TM, Ran, C, Gordon, SG, Stam, AH, Steinberg, S, Borck, G, Koiranen, M, Quaye, L, Adams, HHH, Lehtimäki, T, Sarin, AP, Wedenoja, J, Hinds, DA, Buring, JE, Schürks, M, Ridker, PM, Gudlaug Hrafnsdottir, M, Stefansson, H, Ring, SM, Hottenga, JJ, Penninx, BWJH, Färkkilä, M, Artto, V, Kaunisto, M, Vepsäläinen, S, Malik, R, Heath, AC, Madden, PAF, Martin, NG, Montgomery, GW, Kurki, MI, Kals, M, Mägi, R, Pärn, K, Hämäläinen, E, Huang, H, Byrnes, AE, Franke, L, Huang, J, Stergiakouli, E, Lee, PH, Sandor, C, Webber, C, Cader, Z, Muller-Myhsok, B, Schreiber, S, Meitinger, T, Eriksson, JG, Salomaa, V, Heikkilä, K, Loehrer, E, Uitterlinden, AG, Hofman, A, Van Duijn, CM, Cherkas, L, Pedersen, LM, Stubhaug, A, Nielsen, CS, Männikkö, M, Mihailov, E, Milani, L, Göbel, H, Esserlind, AL, Francke Christensen, A, Folkmann Hansen, T, Werge, T, Kaprio, J, Aromaa, AJ, Raitakari, O, Arfan Ikram, M, Spector, T, Järvelin, MR, Metspalu, A, Kubisch, C, Strachan, DP, Ferrari, MD, Belin, AC, Dichgans, M, Wessman, M, Van den Maagdenberg, AMJM, Zwart, JA, Boomsma, DI, Davey Smith, G
In the version of this article initially published online, the affiliations for Bertram Muller-Myhsok and Patricia Pozo-Rosich were incorrect or incomplete. These errors have been corrected for the print, PDF and HTML versions of this article.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::c1d43033be67033008e6efd4d4b0097e
http://hdl.handle.net/10044/1/85207
http://hdl.handle.net/10044/1/85207
BACKGROUND: Cross-sectional studies have shown an association between the farming environment and a decreased risk of atopic sensitization, mainly related to contact with farm animals in the childhood. OBJECTIVE: Investigate the association of a farm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2b01b7e150858e4be7e273dfaa3c77d9
https://doi.org/10.1111/j.1365-2222.2011.03777.x
https://doi.org/10.1111/j.1365-2222.2011.03777.x
Autor:
Costelloe, SJ, El-Sayed Moustafa, JS, Drenos, F, Palmen, J, Li, Q, Qiao, L, Whiting, S, Thomas, M, Kivimaki, M, Kumari, M, Hingorani, AD, Tzoulaki, I, Järvelin, MR, Marjo-Riitta, J, Ruokonen, A, Aimo, R, Hartikainen, AL, Pouta, A, Walters, RG, Blakemore, AI, Humphries, SE, Coin, LJ, Talmud, PJ
Publikováno v:
Circulation: Cardiovascular Genetics; Vol 5
Background— Copy number variants (CNVs) are a major form of genomic variation, which may be implicated in complex disease phenotypes. However, investigation of the role of CNVs in coronary heart disease (CHD) traits has been limited. Methods and Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd66014f7d571301c49d07750d9c7292
https://ora.ox.ac.uk/objects/uuid:11ecda90-c3a0-4b58-8fa2-0df31a6a6a25
https://ora.ox.ac.uk/objects/uuid:11ecda90-c3a0-4b58-8fa2-0df31a6a6a25
Autor:
D. L. Cousminer, D. J. Berry, N. J. Timpson, W. Ang, E. Thiering, E. M. Byrne, H. R. Taal, V. Huikari, J. P. Bradfield, M. Kerkhof, M. M. Groen Blokhuis, E. Kreiner Moller, M. Marinelli, C. Holst, J. T. Leinonen, J. R. B. Perry, I. Surakka, O. Pietilainen, J. Kettunen, V. Anttila, M. Kaakinen, U. Sovio, A. Pouta, S. Das, V. Lagou, C. Power, I. Prokopenko, D. M. Evans, J. P. Kemp, B. St Pourcain, S. Ring, A. Palotie, E. Kajantie, C. Osmond, T. Lehtimaki, J. S. Viikari, M. Kahonen, N. M. Warrington, S. J. Lye, L. J. Palmer, C. M. T. Tiesler, C. Flexeder, G. W. Montgomery, S. E. Medland, A. Hofman, H. Hakonarson, M. Guxens, M. Bartels, V. Salomaa, J. M. Murabito, J. Kaprio, T. I. A. Sorensen, F. Ballester, H. Bisgaard, D. I. Boomsma, G. H. Koppelman, S. F. A. Grant, V. W. V. Jaddoe, N. G. Martin, J. Heinrich, C. E. Pennell, O. T. Raitakari, J. G. Eriksson, G. D. Smith, E. Hypponen, M. R. Jarvelin, M. I. McCarthy, S. Ripatti, E. Widen, Adair LS, Ang W, Atalay M, van Beijsterveldt T, Bergen N, Benke K, Berry DJ, Boomsma DI, Bradfield JP, Charoen P, Coin L, Cooper C, Cousminer DL, Das S, Davis OS, Dedoussis GV, Elliott P, Estivill X, Evans DM, Feenstra B, Flexeder C, Frayling T, Freathy RM, Gaillard R, Geller F, Gillman M, Grant SF, Groen Blokhuis M, Goh LK, Guxens M, Hakonarson H, Hattersley AT, Haworth CM, Hadley D, Hedebrand J, Heinrich J, Hinney A, Hirschhorn JN, Hocher B, Holloway JW, Holst C, Hottenga JJ, Horikoshi M, Huikari V, Hypponen E, Iñiguez C, Jaddoe VW, Jarvelin MR, Kaakinen M, Kilpeläinen TO, Kirin M, Kowgier M, Lakka HM, Lakka TA, Lange LA, Lawlor DA, Lehtimäki T, Lewin A, Lindgren C, Lindi V, Maggi R, Marsh J, McCarthy MI, Melbye M, Middeldorp C, Millwood I, Mohlke KL, Mook Kanamori DO, Murray JC, Nivard M, Nohr EA, Ntalla I, Oken E, Ong KK, O'Reilly PF, Palmer LJ, Panoutsopoulou K, Pararajasingham J, Pearson ER, Pennell CE, Power C, Price TS, Prokopenko I, Raitakari OT, Rodriguez A, Salem RM, Saw SM, Scherag A, Sebert S, Siitonen N, Simell O, Sørensen TI, Sovio U, Pourcain BS, Strachan DP, Sunyer J, Taal HR, Teo YY, Thiering E, Tiesler C, Timpson NJ, Uitterlinden AG, Valcárcel B, Warrington NM, White S, Widén E, Willemsen G, Wilson JF, Yaghootkar H, Zeggini E, Elks CE, Perry JR, Sulem P, Chasman DI, Franceschini N, He C, Lunetta KL, Visser JA, Byrne EM, Gudbjartsson DF, Esko T, Koller DL, Kutalik Z, Lin P, Mangino M, Marongiu M, McArdle PF, Smith AV, Stolk L, van Wingerden SH, Zhao JH, Albrecht E, Corre T, Ingelsson E, Hayward C, Magnusson PK, Smith EN, Ulivi S, Warrington M, Zgaga L, Alavere H, Amin N, Aspelund T, Bandinelli S, Barroso I, Berenson GS, Bergmann S, Blackburn H, Boerwinkle E, Buring JE, Busonero F, Campbell H, Chanock SJ, Chen W, Cornelis MC, Couper D, Coviello AD, de Faire U, de Geus EJ, Deloukas P, Döring A, Davey Smith G, Easton DF, Eiriksdottir G, Emilsson V, Eriksson J, Ferrucci L, Folsom AR, Foroud T, Garcia M, GASPARINI, PAOLO, Gieger C, Gudnason V, Hall P, Hankinson SE, Ferreli L, Heath AC, Hernandez DG, Hofman A, Hu FB, Illig T, Järvelin MR, Johnson AD, Karasik D, Khaw KT, Kiel DP, Kolcic I, Kraft P, Launer LJ, Laven JS, Li S, Liu J, Levy D, Martin NG, McArdle WL, Mooser V, Murray SS, Nalls MA, Navarro P, Nelis M, Ness AR, Northstone K, Oostra BA, Peacock M, Palotie A, Paré G, Parker AN, Pedersen NL, Peltonen L, Pharoah P, Polasek O, Plump AS, Pouta A, Porcu E, Rafnar T, Rice JP, Ring SM, Rivadeneira F, Rudan I, Sala C, Salomaa V, Sanna S, Schlessinger D, Schork NJ, Scuteri A, Segrè AV, Shuldiner AR, Soranzo N, Srinivasan SR, Tammesoo ML, Tikkanen E, Toniolo D, Tsui K, Tryggvadottir L, Tyrer J, Uda M, van Dam RM, van Meurs JB, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Weedon MN, Wichmann HE, Wright AF, Young L, Zhai G, Zhuang WV, Bierut LJ, Boyd HA, Crisponi L, Demerath EW, van Duijn CM, Econs MJ, Harris TB, Hunter DJ, Loos RJ, Metspalu A, Montgomery GW, Ridker PM, Spector TD, Streeten EA, Stefansson K, Thorsteinsdottir U, Widen E, Murabito JM, Murray A., D'ADAMO, ADAMO PIO
Publikováno v:
Human Molecular Genetics Vol. 22 Issue 13: pp. 2735-2747
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname
Human Molecular Genetics
Hum. Mol. Genet. 22, 2735-2747 (2013)
HUMAN MOLECULAR GENETICS
r-FISABIO. Repositorio Institucional de Producción Científica
Human Molecular Genetics; Vol 22
Cousminer, D L, Berry, D J, Timpson, N J, Ang, W, Thiering, E, Byrne, E M, Taal, H R, Huikari, V, Bradfield, J P, Kerkhof, M, Groen-Blokhuis, M M, Kreiner-Møller, E, Marinelli, M, Holst, C, Leinonen, J T, Perry, J R, Surakka, I, Pietilainen, O P, Kettunen, J, Anttila, V, Kaakinen, M, Sovio, U, Pouta, A, Das, S, Lagou, V, Power, C, Prokopenko, I, Evans, D M, Kemp, J P, St Pourcain, B, Ring, S M, Palotie, A, Kajantie, E, Osmond, C, Lehtimäki, T, Viikari, J S, Kähönen, M, Warrington, N M, Lye, S J, Palmer, L J, Tiesler, C M T, Flexeder, C, Montgomery, G W, Medland, S E, Hofman, A, Hakonarson, H, Guxens, M, Bartels, M, Salomaa, V, Adair, L S, Atalay, M, van Beijsterveldt, C E M, Bergen, N, Benke, K S, Charoen, P, Coin, L, Cooper, C, Davis, O S, Dedoussis, G V, Elliott, P, Estivill, X, Feenstra, B, Frayling, T M, Freathy, R M, Gaillard, R, Geller, F, Gillman, M W, Goh, L K, Hattersley, A T, Haworth, C M, Hadley, D, Hedebrand, J, Hinney, A, Hirschhorn, J N, Hocher, B, Holloway, J W, Hottenga, J J, Horikoshi, M, Iñiguez, C, Järvelin, M R, Kilpeläinen, T O, Kirin, M, Kowgier, M, Lakka, H M, Lakka, T A, Lange, L A, Lawlor, D A, Lewin, A, Lindgren, C M, Lindi, V, Maggi, R, Marsh, J, Melbye, M, Middeldorp, C M, Millwood, I, Mohlke, K L, Mook-Kanamori, D O, Murray, J C, Nivard, M G, Nohr, E A, Ntalla, I, Oken, E, Ong, K K, O'Reilly, P F, Panoutsopoulou, K, Pararajasingham, J, Pearson, E R, Price, T S, Rodriguez, A, Salem, R M, Saw, S M, Scherag, A, Sebert, S, Siitonen, N, Simell, O, Strachan, D P, Sunyer, J, Teo, Y Y, Uitterlinden, A G, Valcárcel, B, White, S, Widén, E, Willemsen, G, Wilson, J F, Yaghootkar, H, Zeggini, E, Elks, C E, Sulem, P, Chasman, D I, Franceschini, N, He, C, Lunetta, K L, Visser, J A, Gudbjartsson, D F, Esko, T, Koller, D L, Kutalik, Z, Lin, P, Mangino, M, Marongiu, M, McArdle, P F, Smith, A V, Stolk, L, van Wingerden, S, Zhao, J H, Albrecht, E, Corre, T, Ingelsson, E, Hayward, C, Magnusson, P K E, Smith, E N, Ulivi, S, Warrington, M, Zgaga, L, Alavere, H, Amin, N, Aspelund, T, Bandinelli, S, Barroso, I, Berenson, G S, Bergmann, S, Blackburn, H, Boerwinkle, E, Buring, J E, Busonero, F, Campbell, H, Chanock, S J, Chen, W, Cornelis, M C, Couper, D, Coviello, A D, d'Adamo, P, de Faire, U, de Geus, E J C, Deloukas, P, Döring, A, Davey Smith, G, Easton, D F, Eiriksdottir, G, Emilsson, V, Ferrucci, L, Folsom, A R, Foroud, T, Garcia, M, Gasparini, P, Gieger, C, Gudnason, V, Hall, P, Hankinson, S E, Ferreli, L, Heath, A C, Hernandez, D G, Hu, F B, Illig, T, Johnson, A D, Karasik, D, Khaw, K T, Kiel, D P, Kolcic, I, Kraft, P, Launer, L J, Laven, J S, Li, S, Liu, J, Levy, D, McArdle, W L, Mooser, V, Murray, S S, Nalls, M A, Navarro, P, Nelis, M, Ness, A R, Northstone, K, Oostra, B A, Peacock, M, Paré, G, Parker, A N, Pedersen, N L, Peltonen, L, Pennell, C E, Pharoah, P, Polasek, O, Plump, A S, Porcu, E, Rafnar, T, Rice, J P, Rivadeneira, F, Rudan, I, Sala, C, Sanna, S, Schlessinger, D, Schork, N J, Scuteri, A, Segrè, A V, Shuldiner, A R, Soranzo, N, Srinivasan, S R, Tammesoo, M L, Tikkanen, E, Toniolo, D, Tsui, K, Tryggvadottir, L, Tyrer, J, Uda, M, Dam, R M, van Meurs, J B, Vollenweider, P, Waeber, G, Wareham, N J, Waterworth, D, Weedon, M N, Wichmann, H E, Wright, A F, Young, L, Zhai, G, Zhuang, W V, Bierut, L J, Boyd, H A, Crisponi, L, Demerath, E W, van Duijn, C M, Econs, M J, Harris, T B, Hunter, D J, Loos, R J, Metspalu, A, Ridker, P M, Spector, T D, Streeten, E A, Stefansson, K, Thorsteinsdottir, U, Murray, A, Murabito, J M, Kaprio, J, Sørensen, T I A, Ballester, F, Bisgaard, H, Boomsma, D I, Koppelman, G H, Grant, S F, Jaddoe, V W, Martin, N G, Heinrich, J, Raitakari, O T, Eriksson, J G, Smith, G D, Hyppönen, E, McCarthy, M I & Ripatti, S 2013, ' Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth pubertal timing and childhood adiposity ', Human Molecular Genetics, vol. 22, no. 13, pp. 2735-2747 . https://doi.org/10.1093/hmg/ddt104
Human Molecular Genetics, 22(13), 2735-2747. Oxford University Press
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname
Human Molecular Genetics
Hum. Mol. Genet. 22, 2735-2747 (2013)
HUMAN MOLECULAR GENETICS
r-FISABIO. Repositorio Institucional de Producción Científica
Human Molecular Genetics; Vol 22
Cousminer, D L, Berry, D J, Timpson, N J, Ang, W, Thiering, E, Byrne, E M, Taal, H R, Huikari, V, Bradfield, J P, Kerkhof, M, Groen-Blokhuis, M M, Kreiner-Møller, E, Marinelli, M, Holst, C, Leinonen, J T, Perry, J R, Surakka, I, Pietilainen, O P, Kettunen, J, Anttila, V, Kaakinen, M, Sovio, U, Pouta, A, Das, S, Lagou, V, Power, C, Prokopenko, I, Evans, D M, Kemp, J P, St Pourcain, B, Ring, S M, Palotie, A, Kajantie, E, Osmond, C, Lehtimäki, T, Viikari, J S, Kähönen, M, Warrington, N M, Lye, S J, Palmer, L J, Tiesler, C M T, Flexeder, C, Montgomery, G W, Medland, S E, Hofman, A, Hakonarson, H, Guxens, M, Bartels, M, Salomaa, V, Adair, L S, Atalay, M, van Beijsterveldt, C E M, Bergen, N, Benke, K S, Charoen, P, Coin, L, Cooper, C, Davis, O S, Dedoussis, G V, Elliott, P, Estivill, X, Feenstra, B, Frayling, T M, Freathy, R M, Gaillard, R, Geller, F, Gillman, M W, Goh, L K, Hattersley, A T, Haworth, C M, Hadley, D, Hedebrand, J, Hinney, A, Hirschhorn, J N, Hocher, B, Holloway, J W, Hottenga, J J, Horikoshi, M, Iñiguez, C, Järvelin, M R, Kilpeläinen, T O, Kirin, M, Kowgier, M, Lakka, H M, Lakka, T A, Lange, L A, Lawlor, D A, Lewin, A, Lindgren, C M, Lindi, V, Maggi, R, Marsh, J, Melbye, M, Middeldorp, C M, Millwood, I, Mohlke, K L, Mook-Kanamori, D O, Murray, J C, Nivard, M G, Nohr, E A, Ntalla, I, Oken, E, Ong, K K, O'Reilly, P F, Panoutsopoulou, K, Pararajasingham, J, Pearson, E R, Price, T S, Rodriguez, A, Salem, R M, Saw, S M, Scherag, A, Sebert, S, Siitonen, N, Simell, O, Strachan, D P, Sunyer, J, Teo, Y Y, Uitterlinden, A G, Valcárcel, B, White, S, Widén, E, Willemsen, G, Wilson, J F, Yaghootkar, H, Zeggini, E, Elks, C E, Sulem, P, Chasman, D I, Franceschini, N, He, C, Lunetta, K L, Visser, J A, Gudbjartsson, D F, Esko, T, Koller, D L, Kutalik, Z, Lin, P, Mangino, M, Marongiu, M, McArdle, P F, Smith, A V, Stolk, L, van Wingerden, S, Zhao, J H, Albrecht, E, Corre, T, Ingelsson, E, Hayward, C, Magnusson, P K E, Smith, E N, Ulivi, S, Warrington, M, Zgaga, L, Alavere, H, Amin, N, Aspelund, T, Bandinelli, S, Barroso, I, Berenson, G S, Bergmann, S, Blackburn, H, Boerwinkle, E, Buring, J E, Busonero, F, Campbell, H, Chanock, S J, Chen, W, Cornelis, M C, Couper, D, Coviello, A D, d'Adamo, P, de Faire, U, de Geus, E J C, Deloukas, P, Döring, A, Davey Smith, G, Easton, D F, Eiriksdottir, G, Emilsson, V, Ferrucci, L, Folsom, A R, Foroud, T, Garcia, M, Gasparini, P, Gieger, C, Gudnason, V, Hall, P, Hankinson, S E, Ferreli, L, Heath, A C, Hernandez, D G, Hu, F B, Illig, T, Johnson, A D, Karasik, D, Khaw, K T, Kiel, D P, Kolcic, I, Kraft, P, Launer, L J, Laven, J S, Li, S, Liu, J, Levy, D, McArdle, W L, Mooser, V, Murray, S S, Nalls, M A, Navarro, P, Nelis, M, Ness, A R, Northstone, K, Oostra, B A, Peacock, M, Paré, G, Parker, A N, Pedersen, N L, Peltonen, L, Pennell, C E, Pharoah, P, Polasek, O, Plump, A S, Porcu, E, Rafnar, T, Rice, J P, Rivadeneira, F, Rudan, I, Sala, C, Sanna, S, Schlessinger, D, Schork, N J, Scuteri, A, Segrè, A V, Shuldiner, A R, Soranzo, N, Srinivasan, S R, Tammesoo, M L, Tikkanen, E, Toniolo, D, Tsui, K, Tryggvadottir, L, Tyrer, J, Uda, M, Dam, R M, van Meurs, J B, Vollenweider, P, Waeber, G, Wareham, N J, Waterworth, D, Weedon, M N, Wichmann, H E, Wright, A F, Young, L, Zhai, G, Zhuang, W V, Bierut, L J, Boyd, H A, Crisponi, L, Demerath, E W, van Duijn, C M, Econs, M J, Harris, T B, Hunter, D J, Loos, R J, Metspalu, A, Ridker, P M, Spector, T D, Streeten, E A, Stefansson, K, Thorsteinsdottir, U, Murray, A, Murabito, J M, Kaprio, J, Sørensen, T I A, Ballester, F, Bisgaard, H, Boomsma, D I, Koppelman, G H, Grant, S F, Jaddoe, V W, Martin, N G, Heinrich, J, Raitakari, O T, Eriksson, J G, Smith, G D, Hyppönen, E, McCarthy, M I & Ripatti, S 2013, ' Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth pubertal timing and childhood adiposity ', Human Molecular Genetics, vol. 22, no. 13, pp. 2735-2747 . https://doi.org/10.1093/hmg/ddt104
Human Molecular Genetics, 22(13), 2735-2747. Oxford University Press
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
The pubertal height growth spurt is a distinctive feature of childhood growth reflecting both the central onset of puberty and local growth factors. Although little is known about the underlying genetics, growth variability during puberty correlates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b26d537e0fd4cd246c06c21c1a378f
https://hdl.handle.net/1959.8/152978
https://hdl.handle.net/1959.8/152978
Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein
Autor:
Ligthart, S, De Vries, PS, Uitterlinden, AG, Hofman, A, Franco, OH, Chasman, DI, Dehghan, A, Dupuis, J, Barbalic, M, Bis, JC, Eiriksdottir, G, Lu, C, Pellikka, N, Wallaschofski, H, Kettunen, J, Henneman, P, Baumert, J, Strachan, DP, Fuchsberger, C, Vitart, V, Wilson, JF, Paré, G, Naitza, S, Rudock, ME, Surakka, I, De Geus, EJC, Alizadeh, BZ, Guralnik, JMD, Shuldiner, A, Tanaka, T, Zee, RYL, Schnabel, RB, Nambi, V, Kavousi, M, Ripatti, S, Nauck, M, Smith, NL, Smith, AV, Sundvall, J, Scheet, P, Liu, Y, Ruokonen, A, Rose, LM, Larson, MG, Hoogeveen, RC, Freimer, NB, Teumer, A, Tracy, RP, Launer, LJ, Buring, JE, Yamamoto, JF, Folsom, AR, Sijbrands, EJG, Pankow, J, Elliott, P, Keaney, JF, Sun, W, Sarin, AP, Fontes, JD, Badola, S, Astor, BC, Pouta, A, Werda, K, Greiser, KH, Kuss, O, Schwabedissen, HEMZ, Thiery, J, Jamshidi, Y, Nolte, IM, Soranzo, N, Spector, TD, Völzke, H, Parker, AN, Aspelund, T, Bates, D, Young, L, Tsui, K, Siscovick, DS, Guo, X, Rotter, JI, Uda, M, Schlessinger, D, Rudan, I, Hicks, AA, Penninx, BW, Thorand, B, Gieger, C, Coresh, J, Willemsen, G, Harris, TB, Järvelin, MR, Rice, K, Radke, D, Salomaa, V, Van Dijk, KW, Boerwinkle, E, Vasan, RS, Ferrucci, L, Gibson, QD
Publikováno v:
Ligthart, S; De Vries, PS; Uitterlinden, AG; Hofman, A; Franco, OH; Chasman, DI; et al.(2015). Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein. PLoS ONE, 10(3). doi: 10.1371/journal.pone.0118859. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6p78j7fd
© 2015 Ligthart et al. Pleiotropic genetic variants have independent effects on different phenotypes. C-reactive protein (CRP) is associated with several cardiometabolic phenotypes. Shared genetic backgrounds may partially underlie these association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::ab1867064f47237b6967be914fc8e34c
http://www.escholarship.org/uc/item/6p78j7fd
http://www.escholarship.org/uc/item/6p78j7fd
Autor:
Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard Costa NL, Hottenga JJ, Kühnel B, Kumar V, Lagou V, Liang L, Luan J, Vidal PM, Mateo Leach I, O'Reilly PF, Peden JF, Rahmioglu N, Soininen P, Speliotes EK, Yuan X, Thorleifsson G, Alizadeh BZ, Atwood LD, Borecki IB, Brown MJ, Charoen P, Cucca F, Das D, de Geus EJ, Dixon AL, Döring A, Ehret G, Eyjolfsson GI, Farrall M, Forouhi NG, Friedrich N, Goessling W, Gudbjartsson DF, Harris TB, Hartikainen AL, Heath S, Hirschfield GM, Hofman A, Homuth G, Hyppönen E, Janssen HL, Johnson T, Kangas AJ, Kema IP, Kühn JP, Lai S, Lathrop M, Lerch MM, Li Y, Liang TJ, Lin JP, Loos RJ, Martin NG, Moffatt MF, Montgomery GW, Munroe PB, Musunuru K, Nakamura Y, O'Donnell CJ, Olafsson I, Penninx BW, Pouta A, Prins BP, Prokopenko I, Puls R, Ruokonen A, Savolainen MJ, Schlessinger D, Schouten JN, Seedorf U, Sen Chowdhry S, Siminovitch KA, Smit JH, Spector TD, Tan W, Teslovich TM, Tukiainen T, Uitterlinden AG, Van der Klauw MM, Vasan RS, Wallace C, Wallaschofski H, Wichmann HE, Willemsen G, Würtz P, Xu C, Yerges Armstrong LM, Alcohol Genome wide Association Consortium, Diabetes Genetics Replication, Meta analyses Study, Genetic Investigation of Anthropometric Traits Consortium, Global Lipids Genetics Consortium, Genetics of Liver Disease Consortium, International Consortium for Blood Pressure, Meta analyses of Glucose, Insulin Related Traits Consortium, Abecasis GR, Ahmadi KR, Boomsma DI, Caulfield M, Cookson WO, van Duijn CM, Froguel P, Matsuda K, McCarthy MI, Meisinger C, Mooser V, Pietiläinen KH, Schumann G, Snieder H, Sternberg MJ, Stolk RP, Thomas HC, Thorsteinsdottir U, Uda M, Waeber G, Wareham NJ, Waterworth DM, Watkins H, Whitfield JB, Witteman JC, Wolffenbuttel BH, Fox CS, Ala Korpela M, Stefansson K, Vollenweider P, Völzke H, Schadt EE, Scott J, Järvelin MR, Elliott P, Kooner JS, PAOLISSO, Giuseppe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3977::a4185907badefbf6ea0e2a83bdb3dec0
http://hdl.handle.net/11591/204402
http://hdl.handle.net/11591/204402
Autor:
Ks, Vimaleswaran, Cavadino A, Dj, Berry, LifeLines Cohort Study investigators, Jorde R, Ak, Dieffenbach, Lu C, Ac, Alves, Hj, Heerspink, Tikkanen E, Eriksson J, Wong A, Mangino M, Ka, Jablonski, Im, Nolte, Dk, Houston, Ts, Ahluwalia, Pj, Most, Pasko D, Zgaga L, Thiering E, Vitart V, Rm, Fraser, Je, Huffman, Ra, Boer, Schöttker B, Ku, Saum, Mi, Mccarthy, Dupuis J, Kh, Herzig, Sebert S, Pouta A, Laitinen J, Me, Kleber, Navis G, Lorentzon M, Jameson K, Arden N, Ja, Cooper, Acharya J, Hardy R, Raitakari O, Ripatti S, Lk, Billings, Lahti J, Osmond C, Bw, Penninx, Rejnmark L, Kk, Lohman, Paternoster L, Rp, Stolk, Dg, Hernandez, Byberg L, Hagström E, Melhus H, Ingelsson E, Mellström D, Ljunggren O, Tzoulaki I, McLachlan S, Theodoratou E, Cm, Tiesler, Jula A, Navarro P, Af, Wright, Polasek O, International Consortium for Blood Pressure (ICBP), Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium, Global Blood Pressure Genetics (Global BPGen) consortium, Caroline Hayward, Jf, Wilson, Rudan I, Salomaa V, Heinrich J, Campbell H, Jf, Price, Karlsson M, Lind L, Michaëlsson K, Bandinelli S, Tm, Frayling, Ca, Hartman, Ti, Sørensen, Sb, Kritchevsky, Bl, Langdahl, Jg, Eriksson, Jc, Florez, Td, Spector, Lehtimäki T, Kuh D, Se, Humphries, Cooper C, Ohlsson C, März W, Mh, Borst, Kumari M, Mika Kivimaki, Tj, Wang, Power C, Brenner H, Grimnes G, van der Harst P, Snieder H, Ad, Hingorani, Pilz S, Jc, Whittaker, Järvelin MR, Hyppönen E
Publikováno v:
Europe PubMed Central
BACKGROUND: Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation approach to test whether 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::425db1caf29762d177e8497e030e1999
https://researchonline.lshtm.ac.uk/id/eprint/1878076/1/NIHMS721970-supplement-Supplementary_Appendix.pdf
https://researchonline.lshtm.ac.uk/id/eprint/1878076/1/NIHMS721970-supplement-Supplementary_Appendix.pdf
Autor:
Vimaleswaran, Kerani S., Cavadino, Alana, Berry, Diane J., Jorde, Rolf, Grimnes, Guri, Dieffenbach, Aida Karina, Lu, Chen, Alves, Alexessander Couto, Heerspink, Hiddo J. Lambers, Tikkanen, Emmi, Eriksson, Joel, Wong, Andrew, Mangino, Massimo, Jablonski, Kathleen A., Nolte, Ilja M., Houston, Denise K., Ahluwalia, Tarunveer Singh, van der Most, Peter J., Pasko, Dorota, Zgaga, Lina, Thiering, Elisabeth, Schöttker, B, Saum, KU, Brenner, H, Järvelin, MR, Tzoulaki, I, Snieder, H, Stolk, RP, Hartman, CA, de Boer, RA, van der Harst, P, Navis, G, de Borst, MH, Lorentzon, M, Mellström, D, Ohlsson, C, Hardy, R, Kuh, D, Cooper, JA, Acharya, J, Humphries, SE, Hingorani, AD, Kumari, M, Kivimaki, M, Spector, TD, Kritchevsky, SB, Lohman, KK, Sørensen, TIA, Frayling, TM, Campbell, H, Theodoratou, E, Fraser, RM, Wilson, JF, Rudan, I, Price, JF, McLachlan, S, Vitart, V, Navarro, P, Huffman, JE, Hayward, C, Wright, AF, Tiesler, CMT, Heinrich, J, McCarthy, MI, Ingelsson, E, Arden, N, Cooper, C, Dupuis, J, Herzig, KH, Sebert, S, Pouta, A, Laitinen, J, Kleber, ME, März, W, Jameson, K, Osmond, C, Raitakari, O, Ripatti, S, Lahti, J, Eriksson, JG, Penninx, BW, Billings, LK, Florez, JC, Rejnmark, L, Langdahl, BL, Paternoster, L, Hernandez, DG, Byberg, L, Michaelsson, K, Hagström, E, Melhus, H, Ljunggren, O, Lind, L, Jula, A, Polasek, O, Salomaa, V, Karlsson, M, Bandinelli, S, Lehtimäki, T, Wang, TJ, Pilz, S, Whittaker, JC
Background Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian randomisation approach to test whether 25(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::046177db6e4ac83b92bcf83af933c962
https://hdl.handle.net/10037/25398
https://hdl.handle.net/10037/25398
Autor:
Koot, MH, Grooten, IJ, Sebert, S, Koiranen, M, Järvelin, MR, Kajantie, E, Painter, RC, Roseboom, TJ, Koot, M H, Grooten, I J, Järvelin, M R, Painter, R C, Roseboom, T J
Publikováno v:
BJOG: An International Journal of Obstetrics & Gynaecology; Jun2017, Vol. 124 Issue 7, p1107-1114, 8p, 1 Diagram, 3 Charts
Autor:
Bennett, A, Sovio, U, Ruokonen, A, Martikainen, H, Pouta, A, Taponen, S, Hartikainen, A, King, V, Elliott, P, Järvelin, MR, McCarthy, M
Publikováno v:
Diabetes. 53(8)
Variation at the insulin gene (INS-)VNTR (variable number of tandem repeats) minisatellite polymorphism has been reported to be associated with both early growth and adult metabolic phenotypes. However, the samples studied have been small and the rel