In silico evo-devo: reconstructing stages in the evolution of animal segmentation

Autor: Hogeweg, Paulien, ten Tusscher, Kirsten H. W. J., Davis, GK, Patel, NH, Peel, A, Akam, M, Couso, JP, Budd, GE, Seaver, EC, Minelli, A, Fusco, G, Tautz, D, Jacobs, DK, Hughes, NC, Fitz-Gibbon, ST, Winchell, CJ, Blair, SS, Wanninger, A, Kristof, A, Brinkmann, N, Chipman, AD, Richmond, DL, Oates, AC, Gold, DA, Runnegar, B, Gehling, JG, Rivera, A, Weisblat, D, Williams, T, Blachuta, B, Hegna, TA, Nagy, LM, Balavoine, G, Bénazéraf, B, Pourquié, O, Mayer, G, Kato, C, Quast, B, Chisholm, RH, Landman, KA, Quinn, LM, Nakamoto, A, Hester, SD, Constantinou, SJ, Blaine, WG, Tewksbury, AB, Matei, MT, Williams, TA, Graham, A, Butts, T, Lumsden, A, Kiecker, C, François, P, Hakim, V, Siggia, ED, Fujimoto, K, Ishihara, S, Kaneko, K, Tusscher, KH, Hogeweg, P, Crombach, A, Salazar-Ciudad, I, Newman, SA, Solé, RV, Pankratz, MJ, Jäckle, H, Crampin, EJ, Hackborn, WW, Maini, PK, Harper, JL, Rosen, BR, White, J, Tusscher, KHWJ, Petersen, CP, Reddien, PW, Martin, BL, Kimelman, D, Young, T, Rowland, JE, Ven, C, Bialecka, M, Novoa, A, Carapuco, M, Nes, J, Graaff, W, Duluc, I, Freund, J-N, Beck, F, Mallo, M, Deschamps, J, Meinhardt, H, Kappen, C, Schughart, K, Ruddle, FH, Sub Theoretical Biology, Dep Biologie, Theoretical Biology and Bioinformatics

Publikováno v: EvoDevo, 7(1). BioMed Central
EvoDevo
EvoDevo, Vol 7, Iss 1, Pp 1-20 (2016)

Background The evolution of animal segmentation is a major research focus within the field of evolutionary–developmental biology. Most studied segmented animals generate their segments in a repetitive, anterior-to-posterior fashion coordinated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb6c20b8e6ee289061928ef0108d68c
https://dspace.library.uu.nl/handle/1874/345640

Pre-fibrillar alpha-Synuclein mutants cause Parkinson's disease-like non-motor symptoms in Drosophila

Autor: Balija, M., Griesinger, C., https://orcid.org/0000-0002-1266-4344, Herzig, A., Zweckstetter, M., Jäckle, H.

Publikováno v: PLoS One

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1874::18dfce831920434fbf71f6b1c68edadc
https://hdl.handle.net/11858/00-001M-0000-000F-0180-811858/00-001M-0000-0027-9F50-3

Bicoid: Morphogen function revisited

Autor: Löhr, U., Chung, H., Beller, M., Jäckle, H.

Publikováno v: Fly
Fly (Austin)

Bicoid (Bcd) functions as a morphogen during Drosophila development. Accordingly, bcd mRNA is maternally localized to the anterior pole of the embryo, and Bcd forms an anterior/posterior gradient, which functions in a concentration dependent fashion.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ca8330acc454fec7083bfa540b610948
https://europepmc.org/articles/PMC3322503/

Drosophila anterior determination is independent of bicoid morphogenic functions but depends on activating versus repressing inputs on the level of target gene enhancers

Autor: Löhr, U., Chung, H., Beller, M., Jäckle, H.

Publikováno v: Mechanisms of Development

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1874::86ffbcc02cee74557ed4bf2c9d97e95b
https://hdl.handle.net/11858/00-001M-0000-0012-D7D0-B11858/00-001M-0000-0012-D7CF-2

buttonhead and D-Sp1: a novel Drosophila gene pair

Autor: Ernst A. Wimmer, Frommer G, Ba, Purnell, Jäckle H

Publikováno v: Europe PubMed Central

The Drosophila gene buttonhead (btd) is a gap-like head segmentation gene which encodes a triple zinc finger protein structurally and functionally related to the human transcription factor Spl. Here we report the pattern of btd expression during embr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f9e050ae02d76cc484147b11d356bfcb
https://pubmed.ncbi.nlm.nih.gov/8892232