Zobrazeno 1 - 10
of 56
pro vyhledávání: '"János Marton"'
Autor:
Enikő Németh, Barbara Gyuricza, Viktória Forgács, Paul Cumming, Gjermund Henriksen, János Marton, Beate Bauer, Pál Mikecz, Anikó Fekete
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13152 (2023)
We have established a method for nucleophilic one-pot, two-step radiosynthesis of the popular opioid receptor radioligand 6-O-(2-[18F]fluoroethyl)-6-O-desmethyl-diprenorphine ([18F]FE-DPN) from the novel precursor 6-O-(2-tosyloxyethyl)-6-O-desmethyl-
Externí odkaz:
https://doaj.org/article/c1fcf105ced7449f8eeb5624b84f7ae9
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 290 (2023)
Hyperphosphorylated tau aggregates, also known as neurofibrillary tangles, are a hallmark neuropathological feature of Alzheimer’s disease (AD). Molecular imaging of tau by positron emission tomography (PET) began with the development of [18F]FDDNP
Externí odkaz:
https://doaj.org/article/9472d01aea864a0bb3d927506b48b319
Publikováno v:
Molecules, Vol 27, Iss 9, p 2863 (2022)
6,14-ethenomorphinans are semisynthetic opiate derivatives containing an ethylene bridge between positions 6 and 14 in ring-C of the morphine skeleton that imparts a rigid molecular structure. These compounds represent an important family of opioid r
Externí odkaz:
https://doaj.org/article/af20237bf0bf4df0875ae85eccac937f
Publikováno v:
Molecules, Vol 25, Iss 20, p 4749 (2020)
Molecular imaging with positron emission tomography (PET) and single photon emission computed tomography (SPECT) is a well-established and important in vivo technique to evaluate fundamental biological processes and unravel the role of neurotransmitt
Externí odkaz:
https://doaj.org/article/948f3473f60e4fad9d04729b8ea28ff4
Publikováno v:
Molecules, Vol 24, Iss 22, p 4190 (2019)
The discovery of endogenous peptide ligands for morphine binding sites occurred in parallel with the identification of three subclasses of opioid receptor (OR), traditionally designated as μ, δ, and κ, along with the more recently defined opioid-r
Externí odkaz:
https://doaj.org/article/aefba5234cc3431eacc40827efe522da
Publikováno v:
Molecules, Vol 18, Iss 6, Pp 7271-7278 (2013)
We have developed a new method for automated production of 2-[18F]fluoroethyl tosylate ([18F]FETos) that enables 18F-alkylation to provide PET tracers with high chemical purity. The method is based on the removal of excess ethylene glycol bistosylate
Externí odkaz:
https://doaj.org/article/2432f01e6a1b4e33a10c1c5c641a4c07
Autor:
Gjermund Henriksen, János Marton
Publikováno v:
Molecules, Vol 17, Iss 10, Pp 11554-11569 (2012)
The semisynthetic oripavine derivative phenethyl orvinol (PEO), a full agonist at opioid receptors (OR), is an attractive structural motif for developing 18F-labeled PET tracers with a high degree of sensitivity for competition between endogenous and
Externí odkaz:
https://doaj.org/article/0900d48eb7484dfdb2dde66ffd2189ff
Publikováno v:
Molecules, Vol 17, Iss 3, Pp 2823-2832 (2012)
The route selection and development of a convenient synthesis of 4-carboxy-4-anilidopiperidines is described. Previous routes were hampered by the low yield of the target esters as well as the inability to convert the esters to the required free acid
Externí odkaz:
https://doaj.org/article/1b2d6bed00f9457399062759d6bb45f8
Autor:
Marjorie R. Levinstein, Emilya N. Ventriglia, Juan L. Gomez, Reece C. Budinich, János Marton, Gjermund Henriksen, Daniel P. Holt, Robert F. Dannals, Martin G. Pomper, Carlos A. Zarate, Jordi Bonaventura, Michael Michaelides
Publikováno v:
Molecular Imaging and Biology. 25:384-390
Autor:
Zoltán Szabó, Sándor Berényi, Bettina M. Schmitt, Paul Cumming, Gjermund Henriksen, Attila Sipos, János Marton
Publikováno v:
ChemistrySelect. 6:5994-6005