The Fungal Iron Chelator Desferricoprogen inhibits atherosclerotic plaque formation

Autor: László Potor, Sikura Katalin Éva, Hajnalka Hegedűs, Dávid Pethő, Zsuzsa Szabó, Zsuzsa M Szigeti, István Pócsi, György Trencsényi, Dezső Szikra, Ildikó Garai, Tamás Gáll, Zsolt Combi, János Kappelmayer György Balla, József Balla

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 13
International Journal of Molecular Sciences, Vol 21, Iss 4746, p 4746 (2020)

Hemoglobin, heme and iron are implicated in the progression of atherosclerosis. Therefore, we investigated whether the hydrophobic fungal iron chelator siderophore, desferricoprogen (DFC) inhibits atherosclerosis. DFC reduced atherosclerotic plaque f

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