Zobrazeno 1 - 10
of 37
pro vyhledávání: '"János Bajdik"'
Publikováno v:
Chemical Engineering Research and Design. 89:1006-1010
The aim of this study was to develop a delayed-release matrix pellet containing atenolol as active pharmaceutical ingredient. The matrix additionally contained trisodium phosphate dodecahydrate as alkalizing pore-former agent to enhance the dissoluti
Publikováno v:
Journal of Drug Delivery Science and Technology. 21:195-200
The aim of this study was to investigate the influence of the wetting liquid on the properties of pellets prepared by extrusion and spheronization. Different grades of ethylcellulose were used as matrix former, with microcrystalline cellulose as fill
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 104:241-247
The aim of this study was to evaluate the applicability of hot melt granulation for the formulation of a pH-sensitive intelligent tablet containing heat- and moisture-sensitive components. An appropriate combination of magnesium trisilicate, aluminiu
Publikováno v:
Pharmaceutical Development and Technology. 17:204-211
The aim of this study was to investigate the effects of alkalizing components and the nature of the wetting liquid on the properties of matrix pellets prepared by extrusion and spheronization. Atenolol was used as an active pharmaceutical ingredient,
Publikováno v:
Chemical Engineering Research and Design. 88:1033-1036
The objective of this study was to investigate the changes in the starch-hydrolysing activity of pancreatin under conditions that can occur during the formulation of multiparticulate systems (granulation, direct compression for the preparation of min
Publikováno v:
Pharmaceutical Development and Technology. 15:354-359
The objective of this study was to evaluate the spreading of the coating liquid on different tablets containing pancreatin and microcrystalline cellulose. The effects of the ratio of the components, the presence of magnesium stearate and the blending
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 74:324-331
Formulation of layered pellets can be a useful method for the preparation of multiparticulate systems. The aims of this work were to study the properties of hydrophilic active agent (pirenzepine dihydrochloride) layers formed on different pellet core
Publikováno v:
Chemical Engineering and Processing: Process Intensification. 49:120-124
The aim of this study was to investigate the effects of the parameters of the spheronization and the nature of the wetting liquid on the properties of matrix pellets prepared by extrusion and spheronization. Ethylcellulose was used as a matrix former
Publikováno v:
Carbohydrate Polymers. 77:530-535
The aim of this study was to evaluate the interaction between the film-forming sodium alginate and lactose monohydrate. This combination is used in the co-spray-drying technique for microencapsulation, but no respect on the structure of the film form
Publikováno v:
Macromolecules. 42:4667-4673
Differences were found in the plasticizing effects of two commonly used softening materials on amorphous chitosan films. The plasticizing efficiencies for glycerol and PEG 400 were found to be similar in mechanical tests, but the changes in the three