Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ján Deván"'
Autor:
Nick Herger, Irina Heggli, Tamara Mengis, Jan Devan, Leonardo Arpesella, Florian Brunner, Oliver Distler, Stefan Dudli
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background The multimodal properties of mesenchymal stromal cells (MSCs), particularly their ability to modulate immune responses is of high interest in translational research. Pro-inflammatory, hypoxic, and 3D culture priming are promising
Externí odkaz:
https://doaj.org/article/b96746a492834b6298b66dbdca8b54f2
Autor:
Tamara Mengis, Natalia Zajac, Laura Bernhard, Irina Heggli, Nick Herger, Jan Devan, Roy Marcus, Florian Brunner, Christoph Laux, Mazda Farshad, Oliver Distler, Stefan Dudli
Publikováno v:
JOR Spine, Vol 7, Iss 2, Pp n/a-n/a (2024)
Abstract Introduction The emerging field of the disc microbiome challenges traditional views of disc sterility, which opens new avenues for novel clinical insights. However, the lack of methodological consensus in disc microbiome studies introduces d
Externí odkaz:
https://doaj.org/article/9bcbe9b2e5c743a5860610bbe970c653
Autor:
Tamara Mengis, Laura Bernhard, Andrea Nüesch, Irina Heggli, Nick Herger, Jan Devan, Roy Marcus, Christoph J. Laux, Florian Brunner, Mazda Farshad, Oliver Distler, Christine L. Le Maitre, Stefan Dudli
Publikováno v:
Cells, Vol 13, Iss 17, p 1402 (2024)
Introduction: The vertebral cartilage endplate (CEP), crucial for intervertebral disc health, is prone to degeneration linked to chronic low back pain, disc degeneration, and Modic changes (MC). While it is known that disc cells express toll-like rec
Externí odkaz:
https://doaj.org/article/e0c15c06dcc14588a9b7a6e35d9b3d9e
Autor:
Tamara Mengis, Nick Herger, Irina Heggli, Jan Devan, José Miguel Spirig, Christoph J. Laux, Florian Brunner, Mazda Farshad, Oliver Distler, Stefan Dudli
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The pain in patients with Modic type 1 changes (MC1) is often due to vertebral body endplate pain, which is linked to abnormal neurite outgrowth in the vertebral body and adjacent endplate. The aim of this study was to understand the role of MC1 bone
Externí odkaz:
https://doaj.org/article/fcd6b0aa8e7f48a085154dc3c9f4b2c4
Autor:
Marie Jarošová, Heidi Mocikova, Jan Oppelt, Leos Kren, Vít Procházka, Katerina Machova Polakova, Pavel Burda, Olaf Merkel, Katerina Cerna, Robert Pytlik, Ana-Iris Schiefer, Marek Trneny, Lenka Zlamalikova, Martin Trbušek, Ján Deván, Lenka Kruzova, Ingrid Simonitsch-Klupp, Václav Šeda, Sonali Sharma, Zuzana Prouzová, Andrea Janíková, Katerina Musilova, Andrew G. Evans, Gabriela Pavlasova, Clive S. Zent, Jiri Mayer, Kvetoslava Liskova, Andrea Marečková, Christoph Kornauth, Marek Mráz
Publikováno v:
Blood. 132:2389-2400
Follicular lymphoma (FL) is a common indolent B-cell malignancy with a variable clinical course. An unfavorable event in its course is histological transformation to a high-grade lymphoma, typically diffuse large B-cell lymphoma. Recent studies show
Publikováno v:
Seminars in oncology. 45(5-6)
The molecular pathogenesis of follicular lymphoma (FL) was partially revealed 3 decades ago, with the discovery of the translocation that brings BCL2 under the influence of immunoglobulin heavy chain enhancers in a vast majority of cases. Despite the