Zobrazeno 1 - 10
of 605
pro vyhledávání: '"J, Windle"'
Autor:
Dongyu Zhang, Amit Kumar, Praveen Bhoopathi, Anjan K Pradhan, Santanu Maji, Padmanabhan Mannangatti, Jolene J Windle, Mark A Subler, Vignesh Vudatha, Jose G Trevino, Esha Madan, Azeddine Atfi, Devanand Sarkar, Rajan Gogna, Swadesh K Das, Luni Emdad, Paul B Fisher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)
Background Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer without effective therapies and with poor prognosis, causing 7% of all cancer-related fatalities in the USA. Considering the lack of effective therapies for this aggressive ca
Externí odkaz:
https://doaj.org/article/9f08c95d77bc4a62afb9ec4fb457d6e4
Autor:
Kazuaki Miyagawa, Hirofumi Tenshin, Patrick L. Mulcrone, Jesus Delgado-Calle, Mark A. Subler, Jolene J. Windle, John M. Chirgwin, G. David Roodman, Noriyoshi Kurihara
Publikováno v:
JCI Insight, Vol 8, Iss 14 (2023)
We previously reported that measles virus nucleocapsid protein (MVNP) expression in osteoclasts (OCLs) of patients with Paget disease (PD) or targeted to the OCL lineage in MVNP-transgenic mice (MVNP mice) increases IGF1 production in osteoclasts (OC
Externí odkaz:
https://doaj.org/article/ca8a54cfa3864041b3e4981930611400
Autor:
Yetirajam Rajesh, Saranya Chidambaranathan Reghupaty, Rachel G. Mendoza, Debashri Manna, Indranil Banerjee, Mark A. Subler, Korri Weldon, Zhao Lai, Shah Giashuddin, Paul B. Fisher, Arun J. Sanyal, Rebecca K. Martin, Mikhail G. Dozmorov, Jolene J. Windle, Devanand Sarkar
Publikováno v:
Hepatology Communications, Vol 6, Iss 3, Pp 561-575 (2022)
Obesity is an enormous global health problem, and obesity‐induced nonalcoholic steatohepatitis (NASH) is contributing to a rising incidence and mortality for hepatocellular carcinoma (HCC). Increase in de novo lipogenesis and decrease in fatty acid
Externí odkaz:
https://doaj.org/article/68bca182ccdc45e18434f8976822db49
Autor:
Catherine A. Vaughan, Shilpa Singh, Mark A. Subler, Jolene J. Windle, Kazushi Inoue, Elizabeth A. Fry, Raghavendra Pillappa, Steven R. Grossman, Brad Windle, W. Andrew Yeudall, Swati Palit Deb, Sumitra Deb
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The mechanisms of how gain-of-function (GOF) mutant p53 drives carcinogenesis are unclear. Here, the authors show that a GOF mutant p53 requires its transactivation capability to induce mouse lung tumors and this is dependent on PLK3 phosphorylation
Externí odkaz:
https://doaj.org/article/54a056e3c31c4f638609e87d39e9e921
Autor:
Nidhi Jariwala, Rachel G. Mendoza, Dawn Garcia, Zhao Lai, Mark A. Subler, Jolene J. Windle, Nitai D. Mukhopadhyay, Paul B. Fisher, Yidong Chen, Devanand Sarkar
Publikováno v:
Hepatology Communications, Vol 3, Iss 9, Pp 1258-1270 (2019)
Oncoprotein staphylococcal nuclease and tudor domain containing 1 (SND1) regulates gene expression at a posttranscriptional level in multiple cancers, including hepatocellular carcinoma (HCC). Staphylococcal nuclease (SN) domains of SND1 function as
Externí odkaz:
https://doaj.org/article/b7f4ac91fec745128b6416691f1b4ef9
Autor:
Daniel Rodriguez-Agudo, Leonel Malacrida, Genta Kakiyama, Tavis Sparrer, Carolina Fortes, Michael Maceyka, Mark A. Subler, Jolene J. Windle, Enrico Gratton, William M. Pandak, Gregorio Gil
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 6, Pp 1087-1098 (2019)
How plasma membrane (PM) cholesterol is controlled is poorly understood. Ablation of the gene encoding the ER stress steroidogenic acute regulatory-related lipid transfer domain (StarD)5 leads to a decrease in PM cholesterol content, a decrease in ch
Externí odkaz:
https://doaj.org/article/b9c9fc18d2e84c2ebc2b6623be3dd211
Autor:
Garrison Komaniecki, Maria Del Carmen Camarena, Eric Gelsleichter, Rachel Mendoza, Mark Subler, Jolene J. Windle, Mikhail G. Dozmorov, Zhao Lai, Devanand Sarkar, Hening Lin
Publikováno v:
Biochemistry. 62:543-553
Publikováno v:
Journal of Operations Management. 69:217-245
Autor:
Peiheng Gan, Michaela Patterson, Alexa Velasquez, Kristy Wang, Di Tian, Jolene J Windle, Ge Tao, Daniel P Judge, Takako Makita, Thomas J Park, Henry M Sucov
Publikováno v:
PLoS Genetics, Vol 15, Iss 10, p e1008354 (2019)
Recent evidence implicates mononuclear diploid cardiomyocytes as a proliferative and regenerative subpopulation of the postnatal heart. The number of these cardiomyocytes is a complex trait showing substantial natural variation among inbred mouse str
Externí odkaz:
https://doaj.org/article/b0cd004e06be40bea92e5a2d3d6387fa
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