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Publikováno v:
Vnitrni lekarstvi. 56(1)
Despite many decades of laboratory and clinical research of pathogenesis bleeding and thrombosis and the search for the identification of the risk factors, the accomplished results are unsatisfactory in clinical praxis. In our article, we discuss inc
Autor:
M, Penka, J, Schwarz, T, Pavlík, K, Indrák, M, Doubek, P, Dulícek, D, Pospísilová, J, Kissová, A, Jonásová, P, Jelínková, A, Hlusí, M, Schutzová, O, Cerná, Y, Brychtová, L, Nováková, Z, Korístek, J, Segethová, V, Vozobulová, I, Hadacová, I, Hochová, J, Voglová, L, Walterová, C, Bodzásová, L, Dusek
Publikováno v:
Vnitrni lekarstvi. 55(11)
The registry of patients treated with Thromboreductin (anagrelide) in the Czech Republic contains data concerning patients that have been treated using this drug since 2004. As of June 2009, the total number of patients was 549. The current analysis
Autor:
M, Penka, J, Schwarz, T, Pavlík, R, Pytiĺk, M, Doubek, P, Dulícek, J, Kissová, A, Hlusi, M, Schutzová, O, Cerná, Y, Brychtová, T, Szotkowski, Z, Volková, J, Seghetová, V, Vozobulová, I, Hadacová, I, Hochová, J, Voglová, L, Dusek
Publikováno v:
Vnitrni lekarstvi. 54(7-8)
The registry of patients treated with Thromboreductine (anagrelid) in the contributing centres in the Czech Republic has been updated with data on the patients receiving this medication since 2004. The original purpose of the registry was to record r
Autor:
M, Penka, J, Schwarz, T, Pavlík, R, Pytlík, M, Doubek, P, Dulícek, D, Pospísilová, J, Kissová, A, Hlusí, M, Schützová, O, Cerná, Y, Brychtová, T, Szotkowski, Z, Volková, J, Seghetová, V, Vozobulová, I, Hadacová, I, Hochová, J, Voglová, T, Lhotanová, B, Bubeník, O, Zapletal, M, Vránová, M, Micaníková, L, Dusek
Publikováno v:
Vnitrni lekarstvi. 53(6)
Since 2005, registers of patients treated with Thromboreductin (anagrelid) kept by some centres in the Czech Republic have been supplied with data concerning patients whose treatment with this preparation started in 2004. The purpose of the register
Autor:
M, Doubek, J, Muzík, T, Szotkowski, V, Koza, P, Cetkovský, T, Kozák, P, Zák, J, Voglová, S, Struncová, L, Dusek, K, Indrák
Publikováno v:
Neoplasma. 54(1)
To assess the prognostic relevance of activating mutations of FLT3 gene on outcome of allogeneic transplantations in AML patients, we performed an analysis of all patients with FLT3 mutations registered in the Czech Acute Leukemia Clinical Register (
Publikováno v:
Vnitrni lekarstvi. 52(9)
Chronic myeloid leukemia in blast phase (BP) is resistant to chemotherapy and majority of patients die within 6 months. Inhibitor Bcr-Abl tyrosine kinase imatinib mesylate dramatically improved outcome of patients in chronic phase (CP) and is also ef
Autor:
M, Penka, M, Doubek, J, Schwarz, R, Pytlík, P, Dulícek, J, Kissová, A, Hlusí, V, Vozobulová, O, Cerná, Y, Brychtová, T, Szotkowski, Z, Volková, J, Seghetová, M, Schutzová, I, Hadacová, I, Hochová, J, Voglová, O, Siroký, D, Belada, T, Lhot'anová, B, Bubeník, M, Vránová, M, Micaníková, L, Dusek
Publikováno v:
Vnitrni lekarstvi. 52(5)
Anagrelide hydrochloride is an effective drug used in patients with ET and other myeloproliferative disorders with thrombocythemia to selectively decrease the number of thrombocytes. Indications for use of anagrelide were described in detail in Czech
Publikováno v:
Casopis lekaru ceskych. 145(1)
Molecular biology methods based on reverse transcription and polymerase chain reaction (RT-PCR) are able to detect the presence of BCR-ABL transcripts in chronic myeloid leukemia (CML). In this study we present our experience with monitoring of resid
Autor:
L, Chrobák, J, Voglová
Publikováno v:
Vnitrni lekarstvi. 51(12)
Idiopathic hypereosinophilic syndrome is a heterogenous group of hematological disorders characterized by eosinophilia (1.5 x 10(9)/l) persistent for more than 6 months, exclusion of reactive eosinophilia from other causes, such as parasitic infectio