The Nonproteolytic Intracellular Domain of Membrane-Type 1 Matrix Metalloproteinase Coordinately Modulates Abdominal Aortic Aneurysm and Atherosclerosis in Mice—Brief Report.

Autor: Silvestro, Michele, Rivera, Cristobal F., Alebrahim, Dornazsadat, Vlahos, John, Pratama, Muhammad Yogi, Lu, Cuijie, Tang, Claudia, Harpel, Zander, Sleiman Tellaoui, Rayan, Zias, Ariadne L., Maldonado, Delphina J., Byrd, Devon, Attur, Mukundan, Mignatti, Paolo, Ramkhelawon, Bhama

Publikováno v: Arteriosclerosis, Thrombosis & Vascular Biology; Oct2022, Vol. 42 Issue 10, p1244-1253, 10p

A personal journey with bioactive lipids.

Autor: Hannun, Yusuf A.¹ yusuf.hannun@stonybrookmedicine.edu

Publikováno v: European Journal of Lipid Science & Technology. Nov2015, Vol. 117 Issue 11, p1814-1831. 18p.

The Susceptibility of Trypanosomatid Pathogens to PI3/mTOR Kinase Inhibitors Affords a New Opportunity for Drug Repurposing.

Autor: Diaz-Gonzalez, Rosario¹ (AUTHOR), Kuhlmann, F. Matthew² (AUTHOR), Galan-Rodriguez, Cristina³ (AUTHOR), da Silva, Luciana Madeira⁴ (AUTHOR), Saldivia, Manuel¹ (AUTHOR), Karver, Caitlin E.⁵ (AUTHOR), Rodriguez, Ana³ (AUTHOR), Beverley, Stephen M.⁴ (AUTHOR), Navarro, Miguel¹ (AUTHOR), Pollastri, Michael P.⁵ (AUTHOR) M.Pollastri@neu.edu

Publikováno v: PLoS Neglected Tropical Diseases. 8/23/2011, Vol. 5 Issue 8, p1-11. 11p.

Novel Insights and Mechanisms of Lipotoxicity-Driven Insulin Resistance.

Autor: Lair, Benjamin^1,2 (AUTHOR) benjamin.lair@inserm.fr, Laurens, Claire^1,2 (AUTHOR) claire.laurens@inserm.fr, Van Den Bosch, Bram^1,2 (AUTHOR) bram.vandenbosch@student.kuleuven.be, Moro, Cedric^1,2 (AUTHOR) cedric.moro@inserm.fr

Publikováno v: International Journal of Molecular Sciences. Sep2020, Vol. 21 Issue 17, p6358-6358. 1p.

The present and future of PI3K inhibitors for cancer therapy.

Autor: Castel P; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA., Toska E; Department of Oncology, Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Biochemistry and Molecular Biology, Johns Hopkins School of Public Health, Baltimore, MD, USA., Engelman JA; Treeline Biosciences, Watertown, MA, USA. jengelman@treelinebiosciences.com., Scaltriti M; Early Oncology, AstraZeneca, Waltham, MA, USA. maurizio.scaltriti@astrazeneca.com.

Publikováno v: Nature cancer [Nat Cancer] 2021 Jun; Vol. 2 (6), pp. 587-597. Date of Electronic Publication: 2021 Jun 17.