Non-nucleoside reverse transcriptase inhibitor-based combination antiretroviral therapy is associated with lower cell- associated HIV RNA and DNA levels compared to protease inhibitor-based therapy

Autor: O Erlwein, A Winston, Peter Reiss, J Villaudy, B Berkhout, M. van der Valk, DP Benschop, A Kalsbeek, Ben Berkhout, M Martens, C Kingsley, T Booiman, Neeltje A. Kootstra, M Wezel, M Moreno-Villanueva, Paolo Garagnani, N Doyle, S Salvioli, BC Elsenga, JA ter Stege, T van der Kuyl, T Su, FR Janssen, BA Schmand, MM Mangas Ruiz, T Sindlinger, I Maurer, A Bürkle, M Capri, W Zikkenheiner, C Libert, M Chiricolo, Robert Leech, Ferdinand Wnm Wit, J Pothof, Caroline A. Sabin, Cblm Majoie, M Gisslén, A Lovell, Mmj Hillebregt, S Zaheri, I Visser, Claudio Franceschi, M de Graaff-Teulen, Alexander O. Pasternak, S Kovalev, M Prins, M Totté, NA Kootstra, H Zetterberg, D de Francesco, JH Cole, K Legg, Mwa Caan, J Schouten, M Klein Twennaar, Jelmer Vroom, J Berkel, AF Girigorie, P Reiss, S Moll, S Dewaele, K Weijer, D Fuchs, Marijn de Bruin, Alan Winston, Chiara Pirazzini, R.A. van Zoest, F Dall'Olio, Davide De Francesco, David J. Sharp, A Keller, AM Harskamp-Holwerda, J Underwood, F. W. Wit, GJ Geurtsen, P Portegies, Ymc Ruijs, M Stott, Margreet Bakker, M Heidenrijk, KW Kooij, Phlt Bisschop, G Guaraldi, L McDonald, C Sabin, AO Pasternak, J Hoeijmakers, Jan M. Prins, HG Ruhé, E Frankin, D Burger

Publikováno v: eLife, Vol 10 (2021)
Elife, 10

Background:It remains unclear whether combination antiretroviral therapy (ART) regimens differ in their ability to fully suppress human immunodeficiency virus (HIV) replication. Here, we report the results of two cross-sectional studies that compared

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be576c147490052df3a9ceab70063d7
https://doi.org/10.7554/eLife.68174

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Correlations between p53-protein accumulation, serum antibodies and gene mutation in colorectal cancer

Autor: Dany Rouillard, Y. Remvikos, J. Villaudy, Marie‐Claude Falzone, Richard Hamelin, M.T. Chaumette, Karen Leroy‐Viard, Brigitte Boissier, Pascal Hammel

Publikováno v: International Journal of Cancer. 81:712-718

Only half of colorectal-cancer patients elicit serum antibodies in response to intratumoral p53-gene mutations. Our study was designed to compare cellular events (p53-protein accumulation and gene mutations) with the presence of circulating anti-p53

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::06618ed379299f4a692d0cbb0e468608
https://doi.org/10.1002/(sici)1097-0215(19990531)81:5<712::aid-ijc7>3.0.co

Purification from Transformed Mouse Fibroblast of a Cell Growth Inhibitor which is an IGF-Binding Protein

Autor: C. Blat, L. Harel, J. Villaudy, F. Troalen, A. Golde, J. Delbé

Publikováno v: Growth Factors. 6:65-75

From medium conditioned by 3T3 cells, we had previously purified an inhibitory factor of Mr 45 kDa which we termed IDF45 (inhibitory diffusible factor). The protein was able to 100% inhibit stimulation induced in CEF by 1% calf serum and to reversibl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9fbbc42db8abce0021bfb50b8ba0fa
https://doi.org/10.3109/08977199209008872

Differences in inhibition by IDF45 (an inhibitory diffusible factor) of early RNA synthesis stimulation induced by pp60 v-src and various mitogens

Autor: J. Delbé, G. Desauty, J. Villaudy, C. Blat, A. Golde, L. Harel

Publikováno v: Journal of Cellular Physiology. 142:359-364

Factors inhibiting cell growth have been isolated from different cell types. However, little information is available concerning their mode of action. A novel growth inhibitory factor of 45 kDa (IDF45) was recently purified to homogeneity from medium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1069bf3cae285b5f0f4f6663aa46e09a
https://doi.org/10.1002/jcp.1041420219