Výsledky vyhledávání - "J, Villacian"

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Lopinavir plus nucleoside reverse-transcriptase inhibitors, lopinavir plus raltegravir, or lopinavir monotherapy for second-line treatment of HIV (EARNEST): 144-week follow-up results from a randomised controlled trial

Autor: James G, Hakim, Jennifer, Thompson, Cissy, Kityo, Anne, Hoppe, Andrew, Kambugu, Joep J, van Oosterhout, Abbas, Lugemwa, Abraham, Siika, Raymond, Mwebaze, Aggrey, Mweemba, George, Abongomera, Margaret J, Thomason, Philippa, Easterbrook, Peter, Mugyenyi, A Sarah, Walker, Nicholas I, Paton, J, Villacian

Publikováno v: The Lancet. Infectious diseases. 18(1)

Millions of HIV-infected people worldwide receive antiretroviral therapy (ART) in programmes using WHO-recommended standardised regimens. Recent WHO guidelines recommend a boosted protease inhibitor plus raltegravir as an alternative second-line comb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5909c85287659e82dce7e44c104b404b
https://pubmed.ncbi.nlm.nih.gov/29108798

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Nucleoside reverse-transcriptase inhibitor cross-resistance and outcomes from second-line antiretroviral therapy in the public health approach: an observational analysis within the randomised, open-label, EARNEST trial

Autor: Nicholas I, Paton, Cissy, Kityo, Jennifer, Thompson, Immaculate, Nankya, Leonard, Bagenda, Anne, Hoppe, James, Hakim, Andrew, Kambugu, Joep J, van Oosterhout, Mary, Kiconco, Silvia, Bertagnolio, Philippa J, Easterbrook, Peter, Mugyenyi, A Sarah, Walker, J, Villacian

Publikováno v: The lancet. HIV. 4(8)

Cross-resistance after first-line antiretroviral therapy (ART) failure is expected to impair activity of nucleoside reverse-transcriptase inhibitors (NRTIs) in second-line therapy for patients with HIV, but evidence for the effect of cross-resistance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a0db7082c78f46f97d8747fbc64cb2f7
https://pubmed.ncbi.nlm.nih.gov/28495563

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Peripheral neuropathy in HIV patients in sub-Saharan Africa failing first-line therapy and the response to second-line ART in the EARNEST trial

Autor: Alejandro, Arenas-Pinto, Jennifer, Thompson, Godfrey, Musoro, Hellen, Musana, Abbas, Lugemwa, Andrew, Kambugu, Aggrey, Mweemba, Dickens, Atwongyeire, Margaret J, Thomason, A Sarah, Walker, Nicholas I, Paton, J, Villacian

Publikováno v: Journal of neurovirology. 22(1)

Sensory peripheral neuropathy (PN) remains a common complication in HIV-positive patients despite effective combination anti-retroviral therapy (ART). Data on PN on second-line ART is scarce. We assessed PN using a standard tool in patients failing f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b619613a15e30650355f55b4387c9e6
https://pubmed.ncbi.nlm.nih.gov/26323809

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Assessment of second-line antiretroviral regimens for HIV therapy in Africa

Publikováno v: The New England journal of medicine. 371(3)

BACKGROUND: The efficacy and toxic effects of nucleoside reverse-transcriptase inhibitors (NRTIs) are uncertain when these agents are used with a protease inhibitor in second-line therapy for human immunodeficiency virus (HIV) infection in resource-l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98db435735b57fbf9213fa058813403f
https://pubmed.ncbi.nlm.nih.gov/25014688

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Spatial-temporal analysis of HIV-1 PR and RT resistance-associated mutations of nucleotide sequences from Western Europe, using vircoTYPE™ HIV-1 assay

Autor: P Van den Eede, M Govaert, K Soom Van, J Villacian, Theresa Pattery

Publikováno v: Journal of the International AIDS Society. 15

Highly effective regimens have drastically improved HIV morbidity and mortality although anti-retro viral resistance remains a limiting factor in disease management. Therefore, analysis of large sequence datasets may provide better insight into drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1079a868a8cabdcebdffe3233801036
https://doi.org/10.7448/ias.15.6.18171

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Changing prevalence of darunavir resistance-associated mutations (DRV RAMs) in clinical samples received for routine resistance testing: 2003-2009

Autor: G De La Rosa, Gaston Picchio, J Villacian, E Lathouwers, K Van der Borght, Theresa Pattery

Publikováno v: Journal of the International AIDS Society

Purpose of the study: Darunavir (DRV) is an HIV protease inhibitor (PI) first approved in 2006. This analysis evaluated the prevalence of DRV resistance associated mutations (RAMs) in clinical samples submitted for routine resistance testing to asses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41330d5d4f560b75cbebc07be3cc59e
http://europepmc.org/articles/PMC3112908

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Effect of lipemia and bilirubinemia on HIV-1 protease and reverse transcriptase genotyping and phenotyping success: a five-year analysis

Autor: Theresa Pattery, M Van Hove, J Villacian, K Van Soom, V Smits, A Van Cauwenberge

Publikováno v: Journal of the International AIDS Society

Background: Interference of clinical laboratory assays by endogenous & exogenous substances in the blood is well known. To date, there are no clear guidelines on the testing of lipemic or bilirubinemic (icteric) plasma in clinical laboratories. A con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e22c66c7e98d1d31ecd032a94de7f5f6
http://europepmc.org/articles/PMC3112925

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Akademický článek

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Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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