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Akademický článek

Integrated drug resistance and leukemic stemness gene-expression scores predict outcomes in large cohort of over 3500 AML patients from 10 trials

Publikováno v: npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)

Abstract In this study, we leveraged machine-learning tools by evaluating expression of genes of pharmacological relevance to standard-AML chemotherapy (ara-C/daunorubicin/etoposide) in a discovery-cohort of pediatric AML patients (N = 163; NCT001360

Externí odkaz: https://doaj.org/article/8d2e5546c18f4cf3998b81a1211405a0

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Akademický článek

Transfusion of ever-pregnant donor red blood cells and mortality of male patients

Autor: Sarah J. Valk, Camila Caram-Deelder, Rolf. H.H. Groenwold, Dorothea Evers, Karen M.K. de Vooght, Daan van de Kerkhof, Marielle J Wondergem, Nathalie C.V. Péquériaux, Francisca Hudig, Jaap Jan Zwaginga, Rutger A. Middelburg, Johanna G. van der Bom

Publikováno v: Haematologica, Vol 999, Iss 1 (2024)

Previous studies found exposure to red blood cell transfusions from female donors who have been pregnant reduces survival in male patients compared to exposure to male donor products, but evidence is not consistent. We postulate the previously observ

Externí odkaz: https://doaj.org/article/34a310a7f32d4eec8b291e50bc0467a1

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A systematic review of the safety and efficacy of convalescent plasma or immunoglobulin treatment for people with severe respiratory viral infections due to coronaviruses or influenza

Autor: Catherine Kimber, Abigail A. Lamikanra, Louise J. Geneen, Josie Sandercock, Carolyn Dorée, Sarah J. Valk, Lise J. Estcourt

Publikováno v: Transfusion medicine (Oxford, England)REFERENCES.

Evaluate the safety and effectiveness of convalescent plasma (CP) or hyperimmune immunoglobulin (hIVIG) in severe respiratory disease caused by coronaviruses or influenza, in patients of all ages requiring hospital admission.We searched multiple elec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bede5125bec8f805337a4aedd8860ec
https://pubmed.ncbi.nlm.nih.gov/36412541

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Akademický článek

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Akademický článek

Oncogenic roles of PRL‐3 in FLT3‐ITD induced acute myeloid leukaemia

Autor: Jung Eun Park, Hiu Fung Yuen, Jian Biao Zhou, Abdul Qader O. Al‐aidaroos, Ke Guo, Peter J. Valk, Shu Dong Zhang, Wee Joo Chng, Cheng William Hong, Ken Mills, Qi Zeng

Publikováno v: EMBO Molecular Medicine, Vol 5, Iss 9, Pp 1351-1366 (2013)

Abstract FLT3‐ITD mutations are prevalent mutations in acute myeloid leukaemia (AML). PRL‐3, a metastasis‐associated phosphatase, is a downstream target of FLT3‐ITD. This study investigates the regulation and function of PRL‐3 in leukaemia

Externí odkaz: https://doaj.org/article/dfc66bebd2a64f1e8f71487871a9c324

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Hyperimmune immunoglobulin for people with COVID-19

Autor: Vanessa Piechotta, Abigail Lamikanra, Erica M. Wood, Sarah J Valk, Catherine E. Kimber, Khai Li Chai, Lise J Estcourt, Nicole Skoetz, Zoe McQuilten, Claire Iannizzi, Cynthia So-Osman, Ina Monsef, David J. Roberts

Publikováno v: Cochrane Database Syst Rev
Cochrane Database of Systematic Reviews, 2021(10):CD015167. John Wiley & Sons Ltd.

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. Using a living systematic review approach, to assess whether hyperimmune immunoglobulin therapy is effective and safe in the treatment of people with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698d955dd9a4e4a4bdd43d779c2ea814
https://ora.ox.ac.uk/objects/uuid:bff4c6ec-1ef0-432b-ac59-74c25fcfda56

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Convalescent plasma or hyperimmune immunoglobulin for people with COVID‐19: a living systematic review

Autor: Vanessa Piechotta, Claire Iannizzi, Khai Li Chai, Sarah J Valk, Catherine Kimber, Elena Dorando, Ina Monsef, Erica M Wood, Abigail A Lamikanra, David J Roberts, Zoe McQuilten, Cynthia So-Osman, Lise J Estcourt, Nicole Skoetz

Publikováno v: Cochrane Database of Systematic Reviews
Cochrane Database Syst Rev

BACKGROUND: Convalescent plasma and hyperimmune immunoglobulin may reduce mortality in patients with viral respiratory diseases, and are being investigated as potential therapies for coronavirus disease 2019 (COVID‐19). A thorough understanding of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551f946cab855a6583cfcf3a8c794a9f
https://ora.ox.ac.uk/objects/uuid:bf9e60f5-ac0d-41a8-871d-b7c1a7d2b5d7

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SARS‐CoV‐2‐neutralising monoclonal antibodies for treatment of COVID‐19

Autor: Nina Kreuzberger, Caroline Hirsch, Khai Li Chai, Eve Tomlinson, Zahra Khosravi, Maria Popp, Miriam Neidhardt, Vanessa Piechotta, Susanne Salomon, Sarah J Valk, Ina Monsef, Christoph Schmaderer, Erica M Wood, Cynthia So-Osman, David J Roberts, Zoe McQuilten, Lise J Estcourt, Nicole Skoetz

Publikováno v: The Cochrane database of systematic reviews, 2021(9):CD013825. John Wiley & Sons Ltd.
Cochrane Database Syst Rev

Background Monoclonal antibodies (mAbs) are laboratory‐produced molecules derived from the B cells of an infected host. They are being investigated as a potential therapy for coronavirus disease 2019 (COVID‐19). Objectives To assess the effective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c79da0132e26135f59a2c2f7645d20c
https://doi.org/10.1002/14651858.cd013825.pub2

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