Zobrazeno 1 - 10
of 25
pro vyhledávání: '"J, Tushinski"'
Autor:
Robert J. Tushinski, Karin M. Luens, Michelle Burton, Liang Jin, L J Murray, Beth L Hill, Sean P. Forestell, Jingyi Chen
Publikováno v:
Human Gene Therapy. 10:1743-1752
We have investigated the ability of several cytokine combinations to improve retrovirus-mediated transduction of human primitive hematopoietic progenitors (PHPs) from mobilized peripheral blood (MPB). Retroviral infection of CD34+ cells was performed
Autor:
Barbara Joyce, Sean Forestall, Jingyi Chen, Chris Reading, Robert J. Tushinski, Jonathan S. Dando, Ernst Böhnlein, Richard J. Rigg
Publikováno v:
New Developments and New Applications in Animal Cell Technology ISBN: 0792350162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4186763763f08c22bc001e288e7b5cf
https://doi.org/10.1007/0-306-46860-3_92
https://doi.org/10.1007/0-306-46860-3_92
Publikováno v:
Experimental hematology. 19(8)
Interleukin 7 (IL-7) stimulates the proliferation of pre-B cells from long-term murine lymphoid cultures and normal bone marrow. In addition, IL-7 stimulates the proliferation of murine T cells, including fetal and adult thymocytes as well as periphe
Publikováno v:
Experimental hematology. 19(4)
Colony-stimulating activity (CSA) can be produced by fibroblasts when stimulated by interleukin 1 (IL-1). We show that like IL-1, interleukin 4 (IL-4) can stimulate 3T3 fibroblasts to produce CSA. Biological and molecular analyses show that a signifi
Publikováno v:
Progress in clinical and biological research. 352
Autor:
Jonathan R. Warner, Ivan T. Oliver, Larry J. Guilbert, E. Richard Stanley, P. Wendy Tynan, Robert J. Tushinski
Publikováno v:
Cell. 28:71-81
CSF-1 is a hemopoietic growth factor that specifically causes the proliferation and differentiation of mononuclear phagocytic cells. Receptors for CSF-1 occur exclusively on cells of the mononuclear phagocytic series (precursor leads to monoblast lea
Autor:
Teresa A. Chiaverotti, Shirley R. Kronheim, Randell T. Libby, David J. Cosman, Gary Braedt, Robert J. Tushinski, Carl J. March, David L. Urdal, Thomas P. Hopp, Diane Y. Mochizuki
Publikováno v:
DNA. 6:221-229
The human granulocyte-macrophage colony stimulating factor (GM-CSF) was expressed and purified from a high-level Escherichia coli secretion vector. A cDNA fragment encoding mature GM-CSF was fused with the aid of a synthetic oligonucleotide to the E.
Publikováno v:
Proceedings of the National Academy of Sciences. 74:2357-2361
We have investigated whether the large (5- to 15-fold) stimulation of synthesis of growth hormone (somatotropin) observed upon exposure of a strain of rat pituitary (GH3) cells to dexamethasone (a synthetic glucocorticoid) arises from a stimulation o
Publikováno v:
Proceedings of the National Academy of Sciences. 84:5267-5271
A murine in vitro assay was developed to measure potentiation of a proliferative response to suboptimal concentrations of the hematopoietic regulatory molecule granulocyte/macrophage colony-stimulating factor by an immature bone marrow population. Th
Autor:
Douglas P. Cerretti, Steven Gillis, Dirk M. Anderson, Kate N. Mckereghan, Kenneth H. Grabstein, Robert J. Tushinski, Åsmund Larsen, Virginia L. Price, Michael A. Cantrell, Diane Y. Mochizuki
Publikováno v:
Proceedings of the National Academy of Sciences. 82:6250-6254
Human granulocyte/macrophage colony-stimulating factor (GM-CSF) is a glycoprotein that is essential for the in vitro proliferation and differentiation of precursor cells into mature granulocytes and macrophages. In this report we have used a mouse GM